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General Information
Symbol
Dmel\towUAS.cCa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Chung
FlyBase ID
FBal0215225
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UASt regulatory sequences drive expression of the full-length tow cDNA GH12583.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expression of towScer\UAS.cCa under the control of Scer\GAL4ap-md544 results in disorganisation of the microchaetae and stunted macrochaetae on the thorax and defects in the scutellum. A multiple wing hair phenotype is seen in the wing and the wing blade is uneven and wavy.

Expression of towScer\UAS.cCa under the control of Scer\GAL4Bx-MS1096 results in a multiple wing hair phenotype in the adult wing. A multiple pre-hair phenotype is seen in pupae expressing towScer\UAS.cCa under the control of Scer\GAL4Bx-MS1096, with most wing cells forming more than one F-actin bundle.

Flies expressing towScer\UAS.cCa under the control of Scer\GAL4Bx-MS1096 have extra bristles in the anterior wing margin and in the wing blade near the most distal region.

Expression of towScer\UAS.cCa under the control of Scer\GAL4hs.2sev has no effect on ommatidial polarity in the eye.

Expression of towScer\UAS.cCa under the control of Scer\GAL4hs.PB using heat shock at 24 hours after puparium formation causes the formation of multiple wing hairs throughout the wing blade. These wing hairs have largely normal polarity.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhanced by
Statement
Reference

Scer\GAL4hs.PB, towUAS.cCa has visible phenotype, enhanceable by zipIIX62/zip[+]

Scer\GAL4hs.PB, towUAS.cCa has visible phenotype, enhanceable by Rho172O/Rho1[+]

Scer\GAL4hs.PB, towUAS.cCa has visible phenotype, enhanceable by rok[+]/Rok2

Scer\GAL4hs.PB, towUAS.cCa has visible phenotype, enhanceable by sqhAX3/sqh[+]

Scer\GAL4hs.PB, towUAS.cCa has visible phenotype, enhanceable by zip[+]/zip1

Suppressed by
Enhancer of
Phenotype Manifest In
Enhanced by
Suppressed by
Enhancer of
Statement
Reference
Additional Comments
Genetic Interactions
Statement
Reference

The planar polarity defects seen in the eyes of animals expressing fzScer\UAS.cAa under the control of Scer\GAL4hs.2sev are enhanced by co-expression of towScer\UAS.cCa (only 26.4% of ommatidia are correctly rotated).

The multiple wing hair phenotype caused by expression of towScer\UAS.cCa under the control of Scer\GAL4hs.PB using heat shock at 24 hours after puparium formation is partially suppressed by co-expression of one of Rho1Scer\UAS.cMa, rokCAT.Scer\UAS or rokαTub84B.PW.

The multiple wing hair phenotype caused by expression of towScer\UAS.cCa under the control of Scer\GAL4hs.PB using heat shock at 24 hours after puparium formation is partially suppressed by one copy of ck13 or ck07130.

The multiple wing hair phenotype caused by expression of towScer\UAS.cCa under the control of Scer\GAL4hs.PB using heat shock at 24 hours after puparium formation is enhanced by co-expression of rokCAT-KG.Scer\UAS.

The multiple wing hair phenotype caused by expression of towScer\UAS.cCa under the control of Scer\GAL4hs.PB using heat shock at 24 hours after puparium formation is enhanced if the flies are also carrying one copy of Rho172O, rok2, sqhAX3, zip1 or zipIIX62.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
towScer\UAS.cCa
towUAS.cCa
Name Synonyms
Saccharomyces cerevisiae UAS construct a of Chung
Secondary FlyBase IDs
    References (1)