FB2026_02 , released June 18, 2026
Allele: Scer\GAL4GSG3315-1
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General Information
Symbol
Scer\GAL4GSG3315-1
Species
S. cerevisiae
Name
FlyBase ID
FBal0220210
Feature type
allele
Associated gene
Scer\GAL4
Associated Insertion(s)
P{Switch2}GSG3315-1
Carried in Construct
Genomic Maps

Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Associated Insertion(s)
    P{Switch2}GSG3315-1
    Cytology
    Description
    Allele components
    Component
    Use(s)
    Inserted element
    P{Switch2}
    Encoded product / tool
    GAL4::GS
    Mutations Mapped to the Genome
    Curation Data
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        distribution deduced from reporter (Gal4 UAS)
        Stage
        Tissue/Position (including subcellular localization)
        Reference
        third instar larval stage
        interneuron | subset of larval ventral nerve cord
        (Nicholson et al., 2008)
        DL fascicle
        (Nicholson et al., 2008)
        VM fascicle
        (Nicholson et al., 2008)
        neuron | subset of larval brain
        (Nicholson et al., 2008)
        scolopale cell
        (Nicholson et al., 2008)
        scolopidial dendritic cap cell
        (Nicholson et al., 2008)
        Additional Information
        Statement
        Reference

        ScerGAL4GSG3315-1 drives mifepristone-inducible expression primarily in neurons. In the ventral nerve cord, strong expression is observed in lateral clusters of 10-15 interneurons/hemisegment; in intersegmental processes at the Fas2-positive DL fascicle, and lateral to the CI fascicle, and along the VM fascicle. Strong expression is observed in a small cluster of neurons in the central region of the brain with processes that project to the contralateral hemisphere. Expression is observed in chordotonal organ attachment and sheath cells.

        (Nicholson et al., 2008)
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Inhibition (using Ctet\tetXTNT-LC.UAS) of Scer\GAL4GSG3315-1 cells significantly reduces larval escape behavior in response to HCl application, compared to controls.

        (Lopez-Bellido et al., 2019)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (1)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (1)
        Reported As
        Symbol Synonym
        Scer\GAL4GSG3315-1
        Name Synonyms
        Secondary FlyBase IDs
          References (3)