FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Tfb5Hsp83.PAF
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General Information
Symbol
Dmel\Tfb5Hsp83.PAF
Species
D. melanogaster
Name
Heat shock protein 83 promoter construct of Aguilar-Fuentes
FlyBase ID
FBal0221773
Feature type
allele
Associated gene
Dmel\Tfb5
Associated Insertion(s)
Carried in Construct
P{Hsp83-Tfb5.AF}
Key Links
Transgenic product class
wild_type
(Aguilar-Fuentes et al., 2008)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Aguilar-Fuentes et al., 2008)
Mutagen
in vitro construct
(Aguilar-Fuentes et al., 2008)
Progenitor genotype
Carried in construct
P{Hsp83-Tfb5.AF}
Cytology
Description

An Hsp83 promoter drives expression of wild-type Tfb5.

(Aguilar-Fuentes et al., 2008)
Allele components
Component
Use(s)
Regulatory region(s)
Hsp83
Encoded product / tool
Tfb5
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Larvae expressing Tfb5Hsp83.PAF show a greater resistance to UV irradiation than control flies.

      (Aguilar-Fuentes et al., 2008)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      Tfb5Hsp83.PAF is a suppressor of visible phenotype of mrn5/mrnEP3605

      (Aguilar-Fuentes et al., 2008)

      Tfb5Hsp83.PAF is a suppressor of lethal | recessive phenotype of mrn3

      (Aguilar-Fuentes et al., 2008)

      Tfb5Hsp83.PAF is a suppressor of lethal | recessive | heat sensitive phenotype of haync2

      (Aguilar-Fuentes et al., 2008)

      Tfb5Hsp83.PAF is a suppressor | partially of sterile phenotype of mrnEP3605/mrn1

      (Aguilar-Fuentes et al., 2008)

      Tfb5Hsp83.PAF is a suppressor | partially of sterile phenotype of mrnEP3605/mrn3

      (Aguilar-Fuentes et al., 2008)

      Tfb5Hsp83.PAF is a suppressor | partially of sterile phenotype of mrn5/mrnEP3605

      (Aguilar-Fuentes et al., 2008)
      NOT Suppressor of
      Statement
      Reference

      Tfb5Hsp83.PAF is a non-suppressor of lethal | recessive phenotype of mrn5

      (Aguilar-Fuentes et al., 2008)

      Tfb5Hsp83.PAF is a non-suppressor of lethal | recessive phenotype of haync2rv7

      (Aguilar-Fuentes et al., 2008)

      Tfb5Hsp83.PAF is a non-suppressor of lethal | recessive | heat sensitive phenotype of haync2rv8

      (Aguilar-Fuentes et al., 2008)

      Tfb5Hsp83.PAF is a non-suppressor of lethal | recessive phenotype of mrn1

      (Aguilar-Fuentes et al., 2008)
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      Tfb5Hsp83.PAF is a suppressor of chaeta phenotype of mrn5/mrnEP3605

      (Aguilar-Fuentes et al., 2008)

      Tfb5Hsp83.PAF is a suppressor of adult thorax phenotype of mrn5/mrnEP3605

      (Aguilar-Fuentes et al., 2008)

      Tfb5Hsp83.PAF is a suppressor of adult abdomen phenotype of mrn5/mrnEP3605

      (Aguilar-Fuentes et al., 2008)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Tfb5Hsp83.PAF can suppress the lethality of mrn3 homozygotes; mrn3 flies carrying one or two copies of Tfb5Hsp83.PAF show low, but significant, rescue of lethality, while mrn3 flies carrying three copies of Tfb5Hsp83.PAF are viable and fertile.

      The defective bristle and thin thorax and abdomen phenotypes seen in mrn5/mrnEP3605 adults are suppressed by Tfb5Hsp83.PAF.

      (Aguilar-Fuentes et al., 2008)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Tfb5Hsp83.PAF
      Name Synonyms
      Heat shock protein 83 promoter construct of Aguilar-Fuentes
      Secondary FlyBase IDs
        References (1)