FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Arf6unspecified
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General Information
Symbol
Dmel\Arf6unspecified
Species
D. melanogaster
Name
FlyBase ID
FBal0230509
Feature type
allele
Associated gene
Dmel\Arf6
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description

    FlyBase curator comment: this entry is used to capture phenotypic information when the particular allele (or allele combination) used by the author could not be determined but the context of the experiment suggests that the phenotype being described is some kind of loss of function.

    (FlyBase Curators, 2025-)
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Arf51Funspecified/Arf51Funspecified mutants exhibit increased ethanol sensitivity, as compared to controls.

        (Acevedo et al., 2015)

        Chromosome segregation and centrosome behaviour occurs normally in mutant spermatocytes.

        Mutant spermatocytes have abnormal kinetics of plasma membrane increase during meiosis I; slow membrane additions characteristic of early cytokinesis is maintained after furrow membrane indentation, and the rapid membrane addition phase never occurs in mutants.

        (Dyer et al., 2007)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        NOT suppressed by
        Statement
        Reference

        Arf6unspecified has chemical sensitive | adult stage phenotype, non-suppressible by Scer\GAL4NP1514/InRCA.UAS.cUa

        (Acevedo et al., 2015)
        NOT Suppressor of
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference

        Expression of InRCA.Scer\UAS.cUa under the control of Scer\GAL4RhoGAP18B-NP1514 does not suppress the increased ethanol sensitivity of Arf51Funspecified/Arf51Funspecified mutant flies.

        Arf51Funspecified/Arf51Funspecified does not suppress the reduced ethanol sensitivity of flies expressing S6kCA.Scer\UAS.cUa under the control of Scer\GAL4elav.PU.

        (Acevedo et al., 2015)
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (2)
        Reported As
        Symbol Synonym
        Arf51Funspecified
        Arf6unspecified
        Name Synonyms
        Secondary FlyBase IDs
          References (3)