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General Information
Symbol
Dmel\cherKK107518
Species
D. melanogaster
Name
FlyBase ID
FBal0234984
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UASt regulatory sequences drive expression of an inverted repeat.

Allele components
Product class / Tool use(s)
Encoded product / tool
Associated Sequence Features
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 1 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

The expression of cherKK107518 under the control of Scer\GAL4Mef2.PU leads to a flightless phenotype, associated with a severe decrease in the number of recognizable sarcomeres in adult indirect flight muscles, as compared to controls; the severe defects in sarcomere structure are enhanced upon additional expression of cherJF02077.

Expression of cherKK107518 driven by Scer\GAL4Mef2.PR leads to irregular sarcomeric actin patterns in third instar larval muscle.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

Co-expression of cherKK107518 and l(2)eflGD11341 driven by Scer\GAL4Mef2.PR leads to myofibril misalignment and severely affected sarcomeric actin patterns in third instar larval muscle.

Co-expression of l(2)eflScer\UAS.P\T.T:Avic\GFP-YFP.Venus partially rescues irregular actin patterns in muscle with cherKK107518 driven by Scer\GAL4Mef2.PR in third instar larvae.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
cherKK107518
Name Synonyms
Secondary FlyBase IDs
    References (9)