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General Information
Symbol
Dmel\Ras85DKK108029
Species
D. melanogaster
Name
FlyBase ID
FBal0235321
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-RASRNAi
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UASt regulatory sequences drive expression of an inverted repeat.

Allele components
Product class / Tool use(s)
Encoded product / tool
Associated Sequence Features
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 1 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expression of Ras85DKK108029 (driven by Scer\GAL4Dll-md23) in type II neuroblast lineage MARCM clones has no significant effect on the clone size or the number of progenitor cells it contains in third instar larvae.

Expression of Ras85DKK108029 under the control of Scer\GAL4phm.PO significantly reduces the circadian rhythmicity of adult emergence after transfer to constant darkness, compared to controls.

The expression of Ras85DKK108029 under the control of Scer\GAL4c564 has no obvious affect on the inflammatory response to Gram-positive bacterial infection or under basal conditions, as compared to controls.

Expression of Ras85DKK108029 in the posterior wing compartment, under the control of Scer\GAL4en-e16E, generates a wing vein differentiation phenotype.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

The overgrowth and increased number of progenitor cells characteristic for cnoR2;scrib1 clones is significantly suppressed by Scer\GAL4Dll-md23-driven expression of Ras85DKK108029 in the mutant clones.

Knockdown of Ras85D in a stepdsRNA.Scer\UAS background, through expression of Ras85DKK108029 in the posterior wing compartment (both transgenes under the control of Scer\GAL4en-e16E) generates a more severe Ras85D phenotype than in a wild-type background. The lateral vein L4 is entirely lost, both cross veins are not differentiated and the distal end of the lateral vein L5 is missing.

Expression of stepScer\UAS.FL suppresses the wing vein defects caused by expression of Ras85DKK108029 in the posterior compartment of the wing, under the control of Scer\GAL4en-e16E.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
Ras85DKK108029
Name Synonyms
Secondary FlyBase IDs
    References (11)