FlyBase Allele Report: Dmel\Arf6[KK108126]

General Information

Symbol

Dmel\Arf6^KK108126

Species

D. melanogaster

Name

FlyBase ID

FBal0235365

Feature type

allele

Associated gene

Dmel\Arf6

Associated Insertion(s)

Carried in Construct

P{KK108126}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

(Keleman et al., 2009.8.5)

Progenitor genotype

Carried in construct

P{KK108126}

Cytology

Description

UASt regulatory sequences drive expression of an inverted repeat.

(Keleman et al., 2009.8.5)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

dsRNA-KK108126

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 1 )

Disease

Evidence

References

model of candidiasis

CEA

(Glittenberg et al., 2022)

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhancer of

Statement

Reference

Arf6^KK108126/Scer\GAL4^Toll-6-D42 is a non-enhancer of abnormal neuroanatomy | larval stage phenotype of Df(2R)ED2076/Rab3^rup

(Mallik et al., 2026)

Suppressor of

Statement

Reference

Arf6^KK108126/Scer\GAL4^Toll-6-D42 is a suppressor of abnormal neuroanatomy phenotype of Asap^B52/Asap^K23

(Mallik et al., 2026)

Arf6^KK108126/Scer\GAL4^Toll-6-D42 is a suppressor of abnormal neurophysiology | larval stage phenotype of Asap^B52/Asap^K23

(Mallik et al., 2026)

Arf6^KK108126/Scer\GAL4^Toll-6-D42 is a suppressor of abnormal size phenotype of Asap^B52/Asap^K23

(Mallik et al., 2026)

NOT Suppressor of

Statement

Reference

Arf6^KK108126/Scer\GAL4^Toll-6-D42 is a non-suppressor of abnormal neuroanatomy | larval stage phenotype of Df(2R)ED2076/Rab3^rup

(Mallik et al., 2026)

Phenotype Manifest In

NOT Enhancer of

Statement

Reference

Arf6^KK108126/Scer\GAL4^Toll-6-D42 is a non-enhancer of presynaptic active zone | larval stage | decreased number phenotype of Df(2R)ED2076/Rab3^rup

(Mallik et al., 2026)

Suppressor of

Statement

Reference

Arf6^KK108126/Scer\GAL4^Toll-6-D42 is a suppressor of NMJ bouton | decreased number phenotype of Asap^B52/Asap^K23

(Mallik et al., 2026)

Arf6^KK108126/Scer\GAL4^Toll-6-D42 is a suppressor of microtubule phenotype of Asap^B52/Asap^K23

(Mallik et al., 2026)

Arf6^KK108126/Scer\GAL4^Toll-6-D42 is a suppressor of presynaptic active zone | increased number phenotype of Asap^B52/Asap^K23

(Mallik et al., 2026)

Arf6^KK108126/Scer\GAL4^Toll-6-D42 is a suppressor of neuromuscular junction phenotype of Asap^B52/Asap^K23

(Mallik et al., 2026)

NOT Suppressor of

Statement

Reference

Arf6^KK108126/Scer\GAL4^Toll-6-D42 is a non-suppressor of presynaptic active zone | larval stage | decreased number phenotype of Df(2R)ED2076/Rab3^rup

(Mallik et al., 2026)

Other

Statement

Reference

Arf6^KK108126, Dcr-2^UAS.cDa, Scer\GAL4^GMR.PF has retina phenotype

(Johnson et al., 2011)

Additional Comments

Genetic Interactions

Statement

Reference

Co-expression of Arf51F^KK108126 and Dcr-2^Scer\UAS.cDa in the retina under the control of Scer\GAL4^GMR.PF results in patterning defects.

(Johnson et al., 2011)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

VDRC

v100726

P{KK108126}VIE-260B

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Arf51F^KK108126

Arf6^KK108126

Name Synonyms

Secondary FlyBase IDs

References (5)

Report Sections

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