FlyBase Allele Report: Dmel\Socs44A[UAS.cRa]

General Information

Symbol

Dmel\Socs44A^UAS.cRa

Species

D. melanogaster

Name

Saccharomyces cerevisiae UAS construct a of Rawlings

FlyBase ID

FBal0240209

Feature type

allele

Associated gene

Dmel\Socs44A

Associated Insertion(s)

Carried in Construct

P{UAS-Socs44A.R}

Also Known As

UAS-socs44A

Key Links

Transgenic product class

cDNA

(Rawlings et al., 2004)

wild_type

(Rawlings et al., 2004)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

cDNA

(Rawlings et al., 2004)

wild_type

(Rawlings et al., 2004)

Mutagen

in vitro construct

(Rawlings et al., 2004)

Progenitor genotype

Carried in construct

P{UAS-Socs44A.R}

Cytology

Description

UASt regulatory sequences drive expression of a full length Socs44A cDNA.

(Rawlings et al., 2004)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

Socs44A

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

visible, with Scer\GAL4^en-e16E

(Rawlings et al., 2004)

Phenotype Manifest In

wing vein | ectopic, with Scer\GAL4^en-e16E

(Rawlings et al., 2004)

wing vein L3, with Scer\GAL4^en-e16E

(Rawlings et al., 2004)

Detailed Description

Statement

Reference

Expression of Socs44A^Scer\UAS.cRa under the control of Scer\GAL4^en-e16E results in the production of ectopic vein vein near the posterior crossvein (predominantly posterior to L5) and a substantial arching of wing vein L3 is seen.

(Rawlings et al., 2004)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Scer\GAL4^en-e16E, Socs44A^UAS.cRa has visible phenotype, enhanceable by hop²/hop[+]

(Rawlings et al., 2004)

Scer\GAL4^en-e16E, Socs44A^UAS.cRa has visible phenotype, enhanceable by argos[+]/aos^W11

(Rawlings et al., 2004)

Suppressed by

Statement

Reference

Scer\GAL4^en-e16E, Socs44A^UAS.cRa has visible phenotype, suppressible by Sos^x122/Sos[+]

(Rawlings et al., 2004)

Scer\GAL4^en-e16E, Socs44A^UAS.cRa has visible phenotype, suppressible by Ras85D^e1B/Ras85D[+]

(Rawlings et al., 2004)

Scer\GAL4^en-e16E, Socs44A^UAS.cRa has visible phenotype, suppressible by Df(2R)Egfr3/+

(Rawlings et al., 2004)

Suppressor of

Statement

Reference

Socs44A^UAS.cRa/Scer\GAL4^en-e16E is a suppressor | partially of visible phenotype of Scer\GAL4^en-e16E, aos^UAS.cMa

(Rawlings et al., 2004)

Socs44A^UAS.cRa/Scer\GAL4^en-e16E is a suppressor of visible phenotype of Scer\GAL4^en-e16E, hop^UAS.cHa

(Rawlings et al., 2004)

Other

Statement

Reference

Scer\GAL4^en-e16E, Socs44A^UAS.cRa, hop³²/hop²⁵ has lethal phenotype

(Rawlings et al., 2004)

Scer\GAL4^en-e16E, Socs44A^UAS.cRa, hop³/hop²⁵ has lethal phenotype

(Rawlings et al., 2004)

Scer\GAL4^en-e16E, Socs44A^UAS.cRa, hop³³/hop²⁵ has lethal phenotype

(Rawlings et al., 2004)

Phenotype Manifest In

Enhanced by

Statement

Reference

Scer\GAL4^en-e16E, Socs44A^UAS.cRa has wing vein | ectopic phenotype, enhanceable by hop²/hop[+]

(Rawlings et al., 2004)

Scer\GAL4^en-e16E, Socs44A^UAS.cRa has wing vein L3 phenotype, enhanceable by hop²/hop[+]

(Rawlings et al., 2004)

Scer\GAL4^en-e16E, Socs44A^UAS.cRa has wing vein | ectopic phenotype, enhanceable by argos[+]/aos^W11

(Rawlings et al., 2004)

Suppressed by

Statement

Reference

Scer\GAL4^en-e16E, Socs44A^UAS.cRa has wing vein | ectopic phenotype, suppressible by Sos^x122/Sos[+]

(Rawlings et al., 2004)

Scer\GAL4^en-e16E, Socs44A^UAS.cRa has wing vein | ectopic phenotype, suppressible by Ras85D^e1B/Ras85D[+]

(Rawlings et al., 2004)

Scer\GAL4^en-e16E, Socs44A^UAS.cRa has wing vein | ectopic phenotype, suppressible by Df(2R)Egfr3/+

(Rawlings et al., 2004)

Suppressor of

Statement

Reference

Socs44A^UAS.cRa/Scer\GAL4^en-e16E is a suppressor of wing vein phenotype of Scer\GAL4^en-e16E, hop^UAS.cHa

(Rawlings et al., 2004)

Socs44A^UAS.cRa/Scer\GAL4^en-e16E is a suppressor of posterior crossvein phenotype of Scer\GAL4^en-e16E, aos^UAS.cMa

(Rawlings et al., 2004)

Socs44A^UAS.cRa/Scer\GAL4^en-e16E is a suppressor | partially of wing vein L4 phenotype of Scer\GAL4^en-e16E, aos^UAS.cMa

(Rawlings et al., 2004)

Additional Comments

Genetic Interactions

Statement

Reference

The ectopic wing vein and arching of wing vein L3 phenotypes caused by expression of Socs44A^Scer\UAS.cRa under the control of Scer\GAL4^en-e16E are enhanced by hop²/+.

The loss of wing veins caused by expression of hop^Scer\UAS.cHa under the control of Scer\GAL4^en-e16E is suppressed by co-expression of Socs44A^Scer\UAS.cRa.

The ectopic wing vein phenotype caused by expression of Socs44A^Scer\UAS.cRa under the control of Scer\GAL4^en-e16E is suppressed by Sos^x122/+, Ras85D^e1B/+ or Df(2R)Egfr3/+ and is enhanced by argos^W11/+.

Co-expression of Socs44A^Scer\UAS.cRa partially suppresses the loss of wing vein phenotype that is seen in flies expressing two copies of argos^Scer\UAS.cMa under the control of Scer\GAL4^en-e16E; the posterior crossvein and the most proximal and distal parts of wing vein L4 are restored.

Co-expression of one copy of Socs44A^Scer\UAS.cRa and one copy of argos^Scer\UAS.cMa under the control of Scer\GAL4^en-e16E results in an almost wild-type wing.

(Rawlings et al., 2004)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

Socs44A^Scer\UAS.cRa

Socs44A^UAS.cRa

Name Synonyms

Saccharomyces cerevisiae UAS construct a of Rawlings

Secondary FlyBase IDs

References (2)

Report Sections

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