FlyBase Allele Report: Dmel\hid[GMR.PU]

General Information

Symbol

Dmel\hid^GMR.PU

Species

D. melanogaster

Name

glass multimer reporter construct of Unknown

FlyBase ID

FBal0240693

Feature type

allele

Associated gene

Dmel\hid

Associated Insertion(s)

Carried in Construct

P{GMR-hid.U}

Also Known As

GMR-hid

Key Links

Transgenic product class

wild_type

(FlyBase Curators, 2025-)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(FlyBase Curators, 2025-)

Mutagen

in vitro construct

(FlyBase Curators, 2025-)

Progenitor genotype

Carried in construct

P{GMR-hid.U}

Cytology

Description

GMR regulatory sequences drive expression of hid.

(FlyBase Curators, 2025-)

FlyBase curator comment: this entry represents a transgenic construct where the particular construct used cannot be determined.

(FlyBase Curators, 2025-)

Allele components

Component

Use(s)

Regulatory region(s)

GMR

engineered transcription regulatory region

Encoded product / tool

hid

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal size | adult stage

(Zhang et al., 2016)

visible

(Hwangbo et al., 2016, Chuang et al., 2014, Lee et al., 2013, Arya and Lakhotia, 2008, Copeland et al., 2007)

visible | adult stage

(Cobb et al., 2023, Zhang et al., 2016)

Phenotype Manifest In

eye

(Cobb et al., 2023, Hwangbo et al., 2016, Chuang et al., 2014, Lee et al., 2013, Arya and Lakhotia, 2008, Copeland et al., 2007)

eye | adult stage

(Zhang et al., 2016)

ommatidium

(Chuang et al., 2014)

Detailed Description

Statement

Reference

hid^GMR.PU leads to small eyes with apoptotic phenotypes in the retina.

(Hwangbo et al., 2016)

hid^GMR.PU induces very small eyes in adults.

(Zhang et al., 2016)

Expression of hid^GMR.PU results in a reduced eye size compared to controls and severe disruption to the ommatidia.

(Chuang et al., 2014)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

hid^GMR.PU has visible phenotype, enhanceable by Hsp60D^UAS.cAa/Scer\GAL4^GMR.PF

(Arya and Lakhotia, 2008)

NOT Enhanced by

Statement

Reference

hid^GMR.PU has visible phenotype, non-enhanceable by ec^EPΔ4

(Copeland et al., 2007)

hid^GMR.PU has visible phenotype, non-enhanceable by ec^SF1.GMR

(Copeland et al., 2007)

Suppressed by

Statement

Reference

hid^GMR.PU has visible phenotype, suppressible by DCAF12^GD10933/Scer\GAL4^GMR.PU

(Hwangbo et al., 2016)

hid^GMR.PU has visible | adult stage phenotype, suppressible by Dad1^UAS.Tag:HA/Scer\GAL4^GMR.PU

(Zhang et al., 2016)

hid^GMR.PU has abnormal size | adult stage phenotype, suppressible by Dad1^UAS.Tag:HA/Scer\GAL4^GMR.PU

(Zhang et al., 2016)

hid^GMR.PU has visible phenotype, suppressible by Hsap\LRRK2^UAS.cCa/Scer\GAL4^GMR.PU

(Chuang et al., 2014)

hid^GMR.PU has visible phenotype, suppressible by rpr^RNAi.RHG.UAS/grim^RNAi.RHG.UAS/hid^RNAi.RHG.UAS/Scer\GAL4^GMR.PF

(Lee et al., 2013)

hid^GMR.PU has visible phenotype, suppressible by Hsp60D^RNAi.Sym.UAS/Scer\GAL4^GMR.PF

(Arya and Lakhotia, 2008)

NOT suppressed by

Statement

Reference

hid^GMR.PU has visible | adult stage phenotype, non-suppressible by Idit^JF02930/Scer\GAL4^GMR.PF

(Cobb et al., 2023)

hid^GMR.PU has visible phenotype, non-suppressible by ec^EPΔ4

(Copeland et al., 2007)

hid^GMR.PU has visible phenotype, non-suppressible by ec^SF1.GMR

(Copeland et al., 2007)

Enhancer of

Statement

Reference

hid^GMR.PU is an enhancer of abnormal neuroanatomy phenotype of dsh⁴

(Sato et al., 2006)

hid^GMR.PU is an enhancer of abnormal neuroanatomy phenotype of fz2^C1

(Sato et al., 2006)

Phenotype Manifest In

Enhanced by

Statement

Reference

hid^GMR.PU has eye phenotype, enhanceable by Hsp60D^UAS.cAa/Scer\GAL4^GMR.PF

(Arya and Lakhotia, 2008)

NOT Enhanced by

Statement

Reference

hid^GMR.PU has eye phenotype, non-enhanceable by ec^EPΔ4

(Copeland et al., 2007)

hid^GMR.PU has eye phenotype, non-enhanceable by ec^SF1.GMR

(Copeland et al., 2007)

Suppressed by

Statement

Reference

hid^GMR.PU has eye phenotype, suppressible by DCAF12^GD10933/Scer\GAL4^GMR.PU

(Hwangbo et al., 2016)

hid^GMR.PU has eye | adult stage phenotype, suppressible by Dad1^UAS.Tag:HA/Scer\GAL4^GMR.PU

(Zhang et al., 2016)

hid^GMR.PU has eye phenotype, suppressible by Hsap\LRRK2^UAS.cCa/Scer\GAL4^GMR.PU

(Chuang et al., 2014)

hid^GMR.PU has ommatidium phenotype, suppressible by Hsap\LRRK2^UAS.cCa/Scer\GAL4^GMR.PU

(Chuang et al., 2014)

hid^GMR.PU has eye phenotype, suppressible by rpr^RNAi.RHG.UAS/grim^RNAi.RHG.UAS/hid^RNAi.RHG.UAS/Scer\GAL4^GMR.PF

(Lee et al., 2013)

hid^GMR.PU has eye phenotype, suppressible by Hsp60D^RNAi.Sym.UAS/Scer\GAL4^GMR.PF

(Arya and Lakhotia, 2008)

NOT suppressed by

Statement

Reference

hid^GMR.PU has eye phenotype, non-suppressible by Idit^JF02930/Scer\GAL4^GMR.PF

(Cobb et al., 2023)

hid^GMR.PU has eye phenotype, non-suppressible by ec^EPΔ4

(Copeland et al., 2007)

hid^GMR.PU has eye phenotype, non-suppressible by ec^SF1.GMR

(Copeland et al., 2007)

hid^GMR.PU has eye phenotype, non-suppressible by Dronc¹¹/Dronc[+]

(Waldhuber et al., 2005)

hid^GMR.PU has eye phenotype, non-suppressible by Dronc⁵¹/Dronc[+]

(Waldhuber et al., 2005)

hid^GMR.PU has eye phenotype, non-suppressible by Dronc³⁰/Dronc[+]

(Waldhuber et al., 2005)

Enhancer of

Statement

Reference

hid^GMR.PU is an enhancer of lamina phenotype of dsh⁴

(Sato et al., 2006)

hid^GMR.PU is an enhancer of eye photoreceptor cell phenotype of dsh⁴

(Sato et al., 2006)

hid^GMR.PU is an enhancer of neuron phenotype of dsh⁴

(Sato et al., 2006)

hid^GMR.PU is an enhancer of lamina phenotype of fz2^C1

(Sato et al., 2006)

hid^GMR.PU is an enhancer of eye photoreceptor cell phenotype of fz2^C1

(Sato et al., 2006)

hid^GMR.PU is an enhancer of neuron phenotype of fz2^C1

(Sato et al., 2006)

Additional Comments

Genetic Interactions

Statement

Reference

Expression of DCAF12^GD10933 driven by Scer\GAL4^GMR.PU partially suppresses apoptotic eye phenotypes in hid^GMR.PU flies.

(Hwangbo et al., 2016)

The expression of Dad1^{Scer\UAS.T:Ivir\HA1} driven by Scer\GAL4^GMR.PU partially suppresses the adult eye size defects induced by hid^GMR.PU.

(Zhang et al., 2016)

The eye defect caused by W^GMR.PU is effectively rescued by expression of P{UAS-RHG.miRNA} (carries W^{miRNA.RHG.Scer\UAS}, grim^{miRNA.RHG.Scer\UAS} and rpr^{miRNA.RHG.Scer\UAS}) under the control of Scer\GAL4^GMR.PF.

(Lee et al., 2013)

A W^GMR.PU background generates a severe ventral-to-dorsal misrouting phenotype in fz2^C1 mutant clone retina.

A W^GMR.PU background generates a severe ventral-to-dorsal misrouting phenotype in dsh⁴ mutant clone retina.

(Sato et al., 2006)

Xenogenetic Interactions

Statement

Reference

Expression of Hsap\LRRK2^Scer\UAS.cCa under the control of Scer\GAL4^GMR.PU partially suppresses the eye phenotypes seen upon expression of hid^GMR.PU.

(Chuang et al., 2014)

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

W^GMR.PU

hid^GMR.PU

Name Synonyms

glass multimer reporter construct of Unknown

Secondary FlyBase IDs

References (20)

Report Sections

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