FlyBase Allele Report: Dmel\amon[RNAi.UAS.cRa]

General Information

Symbol

Dmel\amon^RNAi.UAS.cRa

Species

D. melanogaster

Name

FlyBase ID

FBal0240790

Feature type

allele

Associated gene

Dmel\amon

Associated Insertion(s)

Carried in Construct

P{UAS-amon.RNAi.R}

Also Known As

UAS-AMON-RNAi, uas-amon RNAi, UAS-amon^RNAi

Key Links

Transgenic product class

RNAi_reagent

(Rhea et al., 2010)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Rhea et al., 2010)

Mutagen

in vitro construct

(Rhea et al., 2010, Cook, 2009.12.1)

Progenitor genotype

Carried in construct

P{UAS-amon.RNAi.R}

Cytology

Description

UAS regulatory sequences drive expression of an inverted repeat corresponding to exons 7 and 8 of amon.

(Rhea et al., 2010)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

amon

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal feeding behavior | adult stage | nutrition conditional, with Scer\GAL4^Gr28b.b.4.7

(Zhan et al., 2016)

lethal, with Scer\GAL4^Act.PU

(Rhea et al., 2010)

lethal | heat sensitive, with Scer\GAL4^hs.PU

(Rhea et al., 2010)

Phenotype Manifest In

Detailed Description

Statement

Reference

Expression of amon^{dsRNA.UAS.cBa} under the control of Scer\GAL4^Gr28b.b.4.7 in adults significantly reduces food intake of starved, but not fed, flies, compared to controls.

(Zhan et al., 2016)

The level of aggression seen in males expressing amon^{dsRNA.Scer\UAS.cBa} under the control of Scer\GAL4^50y is similar to controls.

(Davis et al., 2014)

Knockdown of amon in Tk-expressing enterocrine cells, through expression of amon^{dsRNA.Scer\UAS.cBa} under the control of Scer\GAL4^Tkg.PS leads to an increase in lipid levels in the gut and whole body.

(Song et al., 2014)

Expression of amon^{dsRNA.Scer\UAS.cBa} under the control of Scer\GAL4^hs.PU results in 91% lethality. Animals arresting during pupal development fail to undergo head eversion and the abdomen fails to differentiate.

(Rhea et al., 2010)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

amon^RNAi.UAS.cRa, Scer\GAL4^Gr28b.b.4.7 is a suppressor | partially of abnormal feeding behavior | adult stage | conditional phenotype of Crei\ChR1::Vcar\ChR1::Vcar\ChR2^{ReaChR.UAS.Citrine}, Scer\GAL4^Gr28b.b.4.7

(Zhan et al., 2016)

amon^RNAi.UAS.cRa/Scer\GAL4^50y is a suppressor of abnormal behavior | male limited phenotype of Scer\GAL4^50y, tll^JF02545

(Davis et al., 2014)

amon^RNAi.UAS.cRa, Scer\GAL4^50y is a suppressor of abnormal behavior | male limited phenotype of Bhal\NaChBac^UAS.EGFP, Scer\GAL4^50y

(Davis et al., 2014)

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Expression of amon^{dsRNA.Scer\UAS.cBa} fully suppresses the increase in male aggression seen when tll^JF02545 is expressed under the control of Scer\GAL4^50y.

(Davis et al., 2014)

Xenogenetic Interactions

Statement

Reference

Expression of amon^{dsRNA.Scer\UAS.cBa} fully suppresses the increase in male aggression seen when Bhal\NaChBac^{Scer\UAS.T:Avic\GFP-EGFP} is expressed under the control of Scer\GAL4^50y.

(Davis et al., 2014)

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

Bloomington

29009

w^*; P{UAS-amon.RNAi.R}78b

29010

w^*; P{UAS-amon.RNAi.R}69h

Notes on Origin

Discoverer

Comments

Expression of amon^{dsRNA.Scer\UAS.cBa} produces dsRNA which results in dsRNA interference (RNAi) of the amon gene.

(Cook, 2009.12.1)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

amon^RNAi.UAS.cBa

amon^RNAi.UAS.cRa

amon^{dsRNA.Scer\UAS.cBa}

amon^{dsRNA.UAS.cBa}

Name Synonyms

Secondary FlyBase IDs

References (9)

Report Sections

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