FB2021_02, released April 13, 2021

Allele: Scer\GAL4NP6250

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General Information
Symbol
Scer\GAL4NP6250
Species
S. cerevisiae
Name
FlyBase ID
FBal0240898
Feature type
allele
Associated gene
Scer\GAL4
Associated Insertion(s)
P{GawB}NP6250
Carried in Construct
Also Known As
NP6250, JO-CE, JO31-GAL4, JO31
Genomic Maps
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Mutations Mapped to the Genome
     
    Type
    Location
    Additional Notes
    References
    transposable_element_insertion_site
    2L:18,823,547..18,823,685 [+]
    (Suver et al., 2019, Flybrain Neuron Database et al., 2018.6.28, Chang et al., 2016, Lin et al., 2016, Hampel et al., 2015, Mamiya and Dickinson, 2015, Lee et al., 2010, Kamikouchi et al., 2009, Yorozu et al., 2009, Kamikouchi et al., 2006, Otsuna and Ito, 2006)
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
         
        Progenitor genotype
        Cytology
        Nature of the lesion
        Statement
        Reference
        Insertion components
        P{GawB}NP6250
        Product class / Tool use(s)
        Encoded product / tool
        GAL4
        Expression Data
        Reporter Expression
        distribution deduced from reporter (Gal4 UAS)
        Stage
        Tissue/Position (including subcellular localization)
        Reference
        pupal stage
        zone C Johnston organ neuron
        (Lee et al., 2010)
        zone E Johnston organ neuron
        (Lee et al., 2010)
        adult stage
        zone C Johnston organ neuron | subset
        (Hampel et al., 2015, Kamikouchi et al., 2006)
        zone E Johnston organ neuron | subset
        (Hampel et al., 2015, Kamikouchi et al., 2006)
        zone C Johnston organ neuron
        (Flybrain Neuron Database et al., 2018.6.28, Kamikouchi et al., 2009, Yorozu et al., 2009)
        zone E Johnston organ neuron
        (Flybrain Neuron Database et al., 2018.6.28, Kamikouchi et al., 2009, Yorozu et al., 2009)
        gravity sensitive Johnston organ neuron
        (Kamikouchi et al., 2009)
        wind sensitive Johnston organ neuron
        (Yorozu et al., 2009)
        Johnston organ neuron tonically activated by arista deflection
        (Yorozu et al., 2009)
        lobula columnar neuron LC6
        (Flybrain Neuron Database et al., 2018.6.28, Otsuna and Ito, 2006)
        lobula columnar neuron LC9
        (Flybrain Neuron Database et al., 2018.6.28, Otsuna and Ito, 2006)
        lobula columnar neuron LC10
        (Flybrain Neuron Database et al., 2018.6.28, Otsuna and Ito, 2006)
        lobula | restricted
        (Otsuna and Ito, 2006)
        adult anterior optic tract | restricted
        (Otsuna and Ito, 2006)
        anterior optic tubercle | restricted
        (Otsuna and Ito, 2006)
        adult brain | restricted
        (Hampel et al., 2015)
        adult ventral nerve cord | restricted
        (Hampel et al., 2015)
        subregion CM of AMMC zone C
        (Flybrain Neuron Database et al., 2018.6.28)
        subregion CL of AMMC zone C
        (Flybrain Neuron Database et al., 2018.6.28)
        subregion EVM of AMMC zone E
        (Flybrain Neuron Database et al., 2018.6.28)
        subregion EDM of AMMC zone E
        (Flybrain Neuron Database et al., 2018.6.28)
        subregion EDP of AMMC zone E
        (Flybrain Neuron Database et al., 2018.6.28)
        subregion EDC of AMMC zone E
        (Flybrain Neuron Database et al., 2018.6.28)
        Additional Information
        Statement
        Reference

        Scer\GAL4NP6250 expressing zone C/E Johnston organ neurons show overlapping aborizations in the antennal mechanosensory and motor center with one C/E Johnston organ neuron expressing Ecol\lexAGMR27H08.

        (Hampel et al., 2015)

        Scer\GAL4NP6250 expresses in ~200 neurons.

        (Kamikouchi et al., 2009)
         
        Marker for
        zone C Johnston organ neuron
        (Lee et al., 2010)
        zone E Johnston organ neuron
        (Lee et al., 2010)
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Optogenetic activation (using Cnoc\ChR1Cs.IVS.20xUAS.Venus with red light activation) of Scer\GAL4NP6250 neurons results in a significant increase in number of antennal grooming bouts compared to controls.

        (Hampel et al., 2015)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (1)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (1)
        Reported As
        Symbol Synonym
        Scer\GAL4NP6250
        Name Synonyms
        Secondary FlyBase IDs
          References (11)