FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Scer\GAL4Npc1b.PV
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General Information
Symbol
Scer\GAL4Npc1b.PV
Species
S. cerevisiae
Name
Niemann-Pick type C-1b promoter construct of Voght
FlyBase ID
FBal0241345
Feature type
allele
Associated gene
Scer\GAL4
Associated Insertion(s)
Carried in Construct
P{Npc1b-GAL4.V}
Also Known As
NPC1b-GAL4
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Voght et al., 2007)
Progenitor genotype
Carried in construct
P{Npc1b-GAL4.V}
Cytology
Description

A 0.9kb fragment from immediately upstream of the Npc1b start codon is fused upstream of sequence encoding a GAL4 driver.

(Voght et al., 2007)
Allele components
Component
Use(s)
Regulatory region(s)
Npc1b
Npc1b_NPC1b-Gal4
Encoded product / tool
GAL4
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter (Gal4 UAS)
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      third instar larval stage
      embryonic/larval anterior midgut
      (Voght et al., 2007)
      embryonic/larval posterior midgut
      (Voght et al., 2007)
      Additional Information
      Statement
      Reference

      Expression of ScerGAL4Npc1b.PV is seen in larval midgut compartments m2 (anterior end) and m10-12 (posterior end), according to the system defined by Murakami et al., 1999 (FBrf0111439).

      (Voght et al., 2007)
       
      Marker for
      Reflects expression of
      Npc1b
      (Voght et al., 2007)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Scer\GAL4Npc1b.PV
      Name Synonyms
      Niemann-Pick type C-1b promoter construct of Voght
      Secondary FlyBase IDs
        References (11)