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General Information
Symbol
Dmel\gogoD1600
Species
D. melanogaster
Name
FlyBase ID
FBal0242620
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Nucleotide change:

T20272985C

Reported nucleotide change:

T?C

Comment:

T to C mutation in splice donor site.

Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Nucleotide substitution: T?C.

A mutation in the splice donor site for intron 5 is mutated leading to a premature STOP before the transmembrane domain.

Mutation in a splice donor site, resulting in a frameshift after amino acid residue 573, with 28 amino acids added after the frameshift.

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

In gogoH1675/gogoD1600 embryos the axons of ap-expressing neurons are mildly disorganized, with no impact on the overall organization of the Fas2-immunopositive scaffold.

Photoreceptor axons do not project correctly in the optic lobe of gogoD1600 eye-brain complexes in third instar larvae, while the photoreceptor cells themselves are appropriately specified.

All photoreceptors are present and properly located in tangential sections of the eye in animals in which the retina is homozygous (induced using the eyFLP method), but these animals show defects in the projections of photoreceptor axons.

gogoD869/gogoD1600 adult escapers show defects in the projection of photoreceptor axons.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (5)