FlyBase Allele Report: Scer\GAL4[Mef2.5xCD]

General Information

Symbol

Scer\GAL4^Mef2.5xCD

Species

S. cerevisiae

Name

FlyBase ID

FBal0246402

Feature type

allele

Associated gene

Scer\GAL4

Associated Insertion(s)

Carried in Construct

P{Mef2-GAL4.5xCD}

Also Known As

mef2-Gal4

Transgenic product class

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

Mutagen

in vitro construct

(Beckett et al., 2008)

Progenitor genotype

Carried in construct

P{Mef2-GAL4.5xCD}

Cytology

Description

Five copies of a 55bp fragment from the upstream region of Mef2 (the C/D* minimal enhancer fragment) are fused upstream of sequence encoding a GAL4 driver.

(Beckett et al., 2008)

Allele components

Component

Use(s)

Regulatory region(s)

Mef2

Encoded product / tool

GAL4

binary expression system - driver

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

distribution deduced from reporter (Gal4 UAS)

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 14 -- 15

somatic trunk mesoderm

(Beckett et al., 2008)

myotube

(Beckett et al., 2008)

fusion competent cell

(Beckett et al., 2008)

embryonic stage 16 -- 17

embryonic/larval hypodermal muscle cell

(Beckett et al., 2008)

larval stage

larval somatic muscle cell

(Panz et al., 2012)

third instar larval stage

larval somatic muscle cell

(Drechsler et al., 2013)

Additional Information

Statement

Reference

ScerGAL4^Mef2.5xCD drives embryonic expression in somatic mesoderm, developing muscle cells, and body wall muscles.

(Beckett et al., 2008)

Marker for

Reflects expression of

Mef2

(Drechsler et al., 2013, Panz et al., 2012, Beckett et al., 2008)

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal locomotor behavior | second instar larval stage, with Nep4^KK104462

(Panz et al., 2012)

abnormal locomotor behavior | second instar larval stage, with Nep4^UAS.A

(Panz et al., 2012)

lethal - all die before end of larval stage, with Nep4^UAS.A

(Panz et al., 2012)

some die during larval stage, with Nep4^UAS.A

(Panz et al., 2012)

viable, with Nep4^UAS.B

(Panz et al., 2012)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Scer\GAL4^Mef2.5xCD

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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