Ir8a1/Ir8a1 mutant females do not exhibit a significant reduction in feeding preference index for 1% yeast extract versus 5mM sucrose solution, as compared to wild type.
In olfactory preference assays for polyamines, Ir8a1/Ir8a1 flies do not show any significant difference in their attraction to putrescine or cadaverine, as compared to wild type, and females do not show any significant difference in their aversion to oviposit on polyamine-rich substrate (plain, sugar-free 1% agarose supplemented with either putrescine or cadaverine) versus non-supplemented substrate, as compared to wild type.
Ir8a1 mutant adults have no alteration in circadian clock entrainment index for locomotor activity rhythms following a 7 h delay under 25[o] C:27 [o]C temperature cycles in constant light conditions, compared to controls.
Ir8a1 mutants exhibit a reduced DC4 and DP1M glomeruli response to odorants.
Ir8a1 mutant flies demonstrate a significantly reduced avoidance to acetic acid, compared to controls.
Homozygous Ir8a1 mutant animals are viable and fertile.
Ir8a1 mutant class 4 (ac4) coeloconic sensilla lack electrophysiological responsiveness to phenylacetaldehyde, while phenylethyl amine responses are unchanged.
Ir8a1 mutant class 3 (ac3) coeloconic sensilla lack electrophysiological responsiveness to propionic acid.
Electrophysiological responses to γ-hexalactone persist in Ir8a1 mutant class 3 (ac3) coeloconic sensilla.
Electrophysiological responses to acetic acid, but not to 1,4-diaminobutane, are abolished in Ir8a1 mutant class 2 (ac2) coeloconic sensilla.
Electrophysiological responses to ammonia are retained in Ir8a1 mutant class 1 (ac1) coeloconic sensilla.