FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Scer\GAL4Ir8a.PA
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General Information
Symbol
Scer\GAL4Ir8a.PA
Species
S. cerevisiae
Name
Ionotropic receptor 8a promoter construct of Abuin
FlyBase ID
FBal0249374
Feature type
allele
Associated gene
Scer\GAL4
Associated Insertion(s)
Carried in Construct
P{Ir8a-GAL4.A}
Also Known As
IR8a-GAL4
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Abuin et al., 2011)
Progenitor genotype
Carried in construct
P{Ir8a-GAL4.A}
Cytology
Description

Ir8a promoter sequences regulate expression of a GAL4 driver.

(Abuin et al., 2011)
Allele components
Component
Use(s)
Regulatory region(s)
Ir8a
Ir8a_Gal4
Encoded product / tool
GAL4
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter (Gal4 UAS)
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      adult stage
      neuron of coeloconic sensillum of antennal segment 3 | subset
      (Abuin et al., 2011)
      neuron of coeloconic sensillum of antennal segment 3 | subset
      • cilium
      (Abuin et al., 2011)
      neuron of coeloconic sensillum of antennal segment 3 | subset
      • axon
      (Abuin et al., 2011)
      neuron of antennal coeloconic sensillum ac1
      (Silbering et al., 2011)
      neuron of antennal coeloconic sensillum ac2
      (Silbering et al., 2011)
      neuron of antennal coeloconic sensillum ac3
      (Silbering et al., 2011)
      neuron of antennal coeloconic sensillum ac4
      (Silbering et al., 2011)
      neuron of sensillum of sacculus chamber III
      (Silbering et al., 2011)
      adult antennal lobe glomerulus | subset
      (Silbering et al., 2011)
      chamber II of sacculus
      (Sun et al., 2018)
      Additional Information
      Statement
      Reference

      ScerGAL4Ir8a.PA labels neurons in the second chamber of the sacculus but not the hygrosensitive neurons.

      (Sun et al., 2018)

      ScerGAL4Ir8a.PA is expressed in the cell body, cilium and axon of a subset of neurons of sensillum coeloconicum of antennal segment 3.

      (Abuin et al., 2011)

      ScerGAL4Ir8a.PA is expressed in the neurons that innervate the antennal coeloconic sensillum ac1-a4, grooved sensillum of sacculus and in a subset of antennal lobe glomeruli.

      (Silbering et al., 2011)
       
      Marker for
      Reflects expression of
      Ir8a
      (Abuin et al., 2011, Silbering et al., 2011)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Inhibition (using shi1.UAS at 33[o]C) of Scer\GAL4Ir8a.PA cells in adult females significantly reduces attraction to vinegar, with no effect on avoidance of E2-hexenal or acetic acid, compared to controls.

      (Gao et al., 2015)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Scer\GAL4Ir8a.PA
      Name Synonyms
      Ionotropic receptor 8a promoter construct of Abuin
      Secondary FlyBase IDs
        References (18)