FlyBase Allele Report: Scer\GAL4[GMR14H06]

General Information

Symbol

Scer\GAL4^GMR14H06

Species

S. cerevisiae

Name

FlyBase ID

FBal0249978

Feature type

allele

Associated gene

Scer\GAL4

Associated Insertion(s)

Carried in Construct

P{GMR14H06-GAL4}

Also Known As

R14H06-Gal4

Transgenic product class

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

Mutagen

in vitro construct

(Pfeiffer et al., 2011.2.9)

Progenitor genotype

Carried in construct

P{GMR14H06-GAL4}

Cytology

Description

A 3146 base pair fragment from the flanking non-coding or intronic region of rut is fused upstream of a Drosophila core synthetic promoter (DSCP) that is followed by sequence encoding a GAL4 driver.

(Pfeiffer et al., 2011.2.9)

Allele components

Component

Use(s)

Regulatory region(s)

GMR14H06

Encoded product / tool

GAL4

binary expression system - driver

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

distribution deduced from reporter (Gal4 UAS)

Stage

Tissue/Position (including subcellular localization)

Reference

first instar larval stage -- third instar larval stage

Kenyon cell

(Eschbach et al., 2021)

adult stage

adult mushroom body | intense | restricted

(Jenett and Svirskas, 2012.9.24)

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal courtship behavior | conditional, with trr^HMS01019

(Koemans et al., 2017)

abnormal learning | adult stage, with trr^HMS01019

(Koemans et al., 2017)

abnormal neuroanatomy | adult stage, with Hr51^HMS01951

(Raun et al., 2025)

decreased efficacy of long-term memory | adult stage, with Cs1^GD11092

(Raun et al., 2025)

decreased efficacy of long-term memory | adult stage, with Gtpbp1^GD11749

(Raun et al., 2025)

decreased efficacy of long-term memory | adult stage, with Hr51^HMS01951

(Raun et al., 2025)

decreased efficacy of long-term memory | adult stage, with Ldh^GD6887

(Raun et al., 2025)

decreased efficacy of long-term memory | adult stage, with Ldh^HMS00039

(Raun et al., 2025)

decreased efficacy of long-term memory | adult stage, with MFS3^VSH330237

(Raun et al., 2025)

decreased efficacy of long-term memory | adult stage, with Mnn1^GD8117

(Raun et al., 2025)

decreased efficacy of long-term memory | adult stage, with Mnn1^KK101050

(Raun et al., 2025)

decreased efficacy of long-term memory | adult stage, with Pdp^GD7504

(Raun et al., 2025)

decreased efficacy of long-term memory | adult stage, with Set1^HMS00581

(Raun et al., 2025)

decreased efficacy of long-term memory | adult stage, with Set1^HMS01837

(Raun et al., 2025)

decreased efficacy of long-term memory | adult stage, with trr^JF03242

(Raun et al., 2025)

decreased efficacy of long-term memory | adult stage, with trr^KK100280

(Raun et al., 2025)

decreased efficacy of long-term memory | adult stage, with trx^GD4502

(Raun et al., 2025)

decreased efficacy of long-term memory | adult stage, with trx^JF01557

(Raun et al., 2025)

decreased efficacy of long-term memory | adult stage, with Utx^GD4409

(Rots et al., 2023)

decreased efficacy of long-term memory | adult stage, with Utx^HMS00575

(Rots et al., 2023)

decreased efficacy of short-term memory | adult stage, with Hr51^HMS01951

(Raun et al., 2025)

decreased efficacy of short-term memory | adult stage, with Mnn1^GD8117

(Raun et al., 2025)

decreased efficacy of short-term memory | adult stage, with Set1^HMS00581

(Raun et al., 2025)

decreased efficacy of short-term memory | adult stage, with Set1^HMS01837

(Raun et al., 2025)

decreased efficacy of short-term memory | adult stage, with trr^JF03242

(Raun et al., 2025)

decreased efficacy of short-term memory | adult stage, with trr^KK100280

(Raun et al., 2025)

decreased efficacy of short-term memory | adult stage, with Utx^GD4409

(Rots et al., 2023)

decreased efficacy of short-term memory | adult stage, with Utx^HMS00575

(Rots et al., 2023)

decreased rate of courtship behavior, with Utx^GD4409

(Rots et al., 2023)

decreased rate of courtship behavior, with Utx^HMS00575

(Rots et al., 2023)

decreased rate of movement | adult stage, with Utx^HMS00575

(Rots et al., 2023)

decreased sleep | adult stage, with trx^GD4502

(Raun et al., 2025)

increased efficacy of short-term memory | adult stage, with Pdp^GD7504

(Raun et al., 2025)

increased sleep | adult stage, with Utx^HMS00575

(Rots et al., 2023)

Phenotype Manifest In

adult mushroom body gamma-lobe | absent, with Hr51^HMS01951

(Raun et al., 2025)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

Scer\GAL4^GMR14H06, trx^GD4502 has decreased efficacy of long-term memory | adult stage phenotype, suppressible by Ldh^{UAS.ORF.GW.Tag:HA}, Scer\GAL4^GMR14H06

(Raun et al., 2025)

Suppressor of

Statement

Reference

Ldh^{UAS.ORF.GW.Tag:HA}, Scer\GAL4^GMR14H06 is a suppressor of decreased efficacy of long-term memory | adult stage phenotype of Scer\GAL4^GMR14H06, trx^GD4502

(Raun et al., 2025)

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

48667

w¹¹¹⁸; P{GMR14H06-GAL4}attP2

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Scer\GAL4^GMR14H06

Name Synonyms

Secondary FlyBase IDs

References (13)

Report Sections

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