Thermogenetic activation (using TrpA1^UAS.(B).cKa at 32[o]C) of Scer\GAL4^GMR50H05 cells in adults in a particular position within a chamber results in a significant increase in associative aversive place memory, compared to controls.

Preactivation (using TrpA1^UAS.(B).cKa at 32[o]C, or Rnor\Trpm8^UAS.EGFP, at 15[o]C before training) of Scer\GAL4^GMR50H05 cells does not affect latency of escape from heat or associative aversive (heat) place memory, compared to controls.

Thermogenetic activation (using TrpA1^UAS.(B).cKa at 32[o]C) of Scer\GAL4^GMR50H05 cells in adult females significantly increases food intake in sated flies and in starved flies in some dietary conditions, compared to controls; there is no increase in food intake when activation occurs only when flies are not in contact with the food or when food has a bitter taste; there is a significant increase in the preference for food over water in sated, but not starved, flies, and for D-glucose over L-glucose in sated and starved flies, compared to controls; the rate of proboscis extension in response to sucrose is significantly increased in sated, but not starved, flies compared to controls, to the extent that it is similar to that of starved controls; there is no effect on climbing ability, compared to controls. In associative memory tests, activation during training significantly reduces medium-term appetitive olfactory memory in starved flies, compared to controls; activation during testing significantly increases medium-term appetitive olfactory memory in sated flies, compared to controls; activation does not induce odor memory formation in the absence of rewards. Activation of a reduced number of Scer\GAL4^GMR50H05 cells (using Ecol\lexA^Trh.PR and Scer\GAL80^{IVS.WPRE.8xlexAop}) does not result in increased food intake in sated flies.

Acute inhibition (using shi^1.UAS at 31-34[o]C) of Scer\GAL4^GMR50H05 cells in adult females significantly reduces food intake of starved flies, with no effect on sated flies, compared to controls; there is no effect on the rate of proboscis extension in response to sucrose, or preference for D-glucose over L-glucose, compared to controls; there is no effect on climbing ability, compared to controls; inhibition during training and testing significantly reduces medium-term appetitive olfactory memory in starved flies, compared to controls.

Chronic inhibition (using Ctet\TeTxLC^UAS.cUa or Hsap\KCNJ2^UAS.cUa.EGFP) of Scer\GAL4^GMR50H05 cells in adult females does not affect food intake in starved flies, compared to controls.

Optogenetic activation (using Crei\ChR2^UAS.cSa with 470 nm (blue) light) of Scer\GAL4^GMR50H05 cells in larvae results in a significant increase in escape behaviors, compared to controls.

Scer\GAL4^GMR50H05, TrpA1^UAS.(B).cKa has abnormal feeding behavior | adult stage phenotype, suppressible | partially by Trhn^RNAi.1.UAS/Scer\GAL4^GMR50H05

Scer\GAL4^GMR50H05, TrpA1^UAS.(B).cKa has abnormal feeding behavior | adult stage phenotype, suppressible | partially by Scer\GAL4^GMR50H05/Trhn^RNAi.2.UAS

Trhn^RNAi.1.UAS/Scer\GAL4^GMR50H05 is a suppressor | partially of abnormal feeding behavior | adult stage phenotype of Scer\GAL4^GMR50H05, TrpA1^UAS.(B).cKa

Scer\GAL4^GMR50H05/Trhn^RNAi.2.UAS is a suppressor | partially of abnormal feeding behavior | adult stage phenotype of Scer\GAL4^GMR50H05, TrpA1^UAS.(B).cKa