FlyBase Allele Report: Scer\GAL4[GMR78A01]

FB2026_01 , released March 12, 2026

FB2026_01 , released March 12, 2026

Allele: Scer\GAL4^GMR78A01

General Information

Symbol

Scer\GAL4^GMR78A01

Species

S. cerevisiae

Name

FlyBase ID

FBal0254952

Feature type

allele

Associated gene

Associated Insertion(s)

Carried in Construct

P{GMR78A01-GAL4}

Also Known As

R78A01-Gal4

Transgenic product class

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

Mutagen

in vitro construct

(Pfeiffer et al., 2011.2.9)

Progenitor genotype

Carried in construct

P{GMR78A01-GAL4}

Cytology

Description

A 2139 base pair fragment from the flanking non-coding or intronic region of nub is fused upstream of a Drosophila core synthetic promoter (DSCP) that is followed by sequence encoding a GAL4 driver.

(Pfeiffer et al., 2011.2.9)

Allele components

Component

Use(s)

Regulatory region(s)

Encoded product / tool

binary expression system - driver

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

distribution deduced from reporter (Gal4 UAS)

Stage

Tissue/Position (including subcellular localization)

Reference

third instar larval stage

larval multidendritic class II neuron

(Hu et al., 2017)

larval multidendritic class III neuron

(Hu et al., 2017)

larval multidendritic class IV neuron

(Hu et al., 2017)

prow | restricted

(Jenett and Svirskas, 2012.9.24)

flange | restricted

(Jenett and Svirskas, 2012.9.24)

gall | restricted

(Jenett and Svirskas, 2012.9.24)

bulb | intense | restricted

(Jenett and Svirskas, 2012.9.24)

antennal mechanosensory and motor center | faint | restricted

(Jenett and Svirskas, 2012.9.24)

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal locomotor behavior | larval stage | conditional, with Cnoc\ChR1::Csub\ChR^{CsChrimson.IVS.20xUAS.Venus}, Scer\GAL80^ppk.1.0

(Hu et al., 2017)

abnormal pain response | larval stage, with Ctet\tetX^TNT-LC.UAS

(Hu et al., 2017)

Phenotype Manifest In

Detailed Description

Statement

Reference

Inhibition (using Ctet\tetX^TNT-LC.UAS) of Scer\GAL4^GMR78A01 cells in larvae significantly reduces nociceptive movement responses following stimulation with a von Frey filament, compared to controls; there is no effect on the response to gentle touch, compared to controls.

Optogenetic activation (using Cnoc\ChR1::Csub\ChR^{CsChrimson.IVS.20xUAS.Venus} with 625 nm (red) light) of a subset of Scer\GAL4^GMR78A01 cells (activation restricted using Scer\GAL80^ppk.1.0) in larvae results in continuous rolling without contractions in the absence of pain stimuli, this is not seen in controls.

(Hu et al., 2017)

External Data

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

39985

w¹¹¹⁸; P{GMR78A01-GAL4}attP2

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Scer\GAL4^GMR78A01

Name Synonyms

Secondary FlyBase IDs

References (5)

Report Sections