FB2021_01, released Feb 18, 2021

Allele: Dmel\mir-bftUAS.DsRed2

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General Information
Symbol
Dmel\mir-bftUAS.DsRed2
Species
D. melanogaster
Name
FlyBase ID
FBal0257038
Feature type
allele
Associated gene
Dmel\mir-bft
Associated Insertion(s)
Carried in Construct
P{UAS-DsRed-mir-263a}
Also Known As
UAS-miR-263a
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
in vitro construct - regulatory fusion
(Hilgers et al., 2010)
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
       
      Progenitor genotype
      Carried in construct
      P{UAS-DsRed-mir-263a}
      Cytology
      Nature of the lesion
      Statement
      Reference

      UASt regulatory sequences drive expression of DsRed2 followed by a 3'UTR into which a 300bp genomic fragment containing the mir-263a miRNA hairpin (which is encoded by bft) has been cloned.

      (Hilgers et al., 2010)
      Allele components
      Product class / Tool use(s)
      Regulatory region(s)
      UASt
      Encoded product / tool
      mir-bft
      Tagged with
      DsRed2
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Scer\GAL4mir-bft-Δ263a-G4/mir-bftUAS.DsRed2 rescues mir-bft24/mir-bftΔ263a-G4

      (Hilgers et al., 2010)
      Partially rescues

      mir-bftUAS.DsRed2 partially rescues mir-bft24/mir-bftΔ263a

      (Hilgers et al., 2010)
      Comments

      Expression of bftScer\UAS.T:Disc\RFP-DsRed2 under the control of Scer\GAL4bft-Δ263a-G4 rescues the loss of interommatidial bristles which is seen in bftΔ263a-G4/bft24 flies.

      Leaky expression of bftScer\UAS.T:Disc\RFP-DsRed2 in the absence of a Scer\GAL4 driver partially rescues the loss of interommatidial bristles which is seen in bftΔ263a/bft24 flies.

      (Hilgers et al., 2010)
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      bftScer\UAS.T:Disc\RFP-DsRed2
      bftUAS.DsRed2
      mir-bftUAS.DsRed2
      Name Synonyms
      Secondary FlyBase IDs
        References (4)