FlyBase Allele Report: Dmel\Tgi[HMS00981]

General Information

Symbol

Dmel\Tgi^HMS00981

Species

D. melanogaster

Name

FlyBase ID

FBal0257650

Feature type

allele

Associated gene

Dmel\Tgi

Associated Insertion(s)

Carried in Construct

P{TRiP.HMS00981}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Ni et al., 2010.12.1)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Ni et al., 2010.12.1)

Mutagen

in vitro construct

(Ni et al., 2010.12.1)

Progenitor genotype

Carried in construct

P{TRiP.HMS00981}

Cytology

Description

UAS regulatory sequences drive expression of a short inverted repeat.

(Ni et al., 2010.12.1)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

dsRNA-HMS00981

Also carries

loxP

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

Expression of Tgi^HMS00981 under the control of Scer\GAL4^C587 has no apparent germarium phenotype.

(Li et al., 2015)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

Scer\GAL4^C587/Tgi^HMS00981 is a suppressor of female sterile phenotype of Scer\GAL4^C587, yki^{RNAi.UASp.cLa}

(Li et al., 2015)

Scer\GAL4^C587/Tgi^HMS00981 is a suppressor of neoplasia | female | adult stage phenotype of Scer\GAL4^C587, yki^{RNAi.UASp.cLa}

(Li et al., 2015)

Scer\GAL4^C587/Tgi^HMS00981 is a suppressor | partially of neoplasia | female | adult stage phenotype of Scer\GAL4^C587, vg^UAS.cKa

(Li et al., 2015)

Scer\GAL4^C587/Tgi^HMS00981 is a suppressor | partially of neoplasia | female | adult stage phenotype of Scer\GAL4^C587, ci^{RNAi.UASp.cLa}

(Li et al., 2015)

Phenotype Manifest In

Suppressor of

Statement

Reference

Scer\GAL4^C587/Tgi^HMS00981 is a suppressor of germarium phenotype of Scer\GAL4^C587, yki^{RNAi.UASp.cLa}

(Li et al., 2015)

Scer\GAL4^C587/Tgi^HMS00981 is a suppressor | partially of germarium phenotype of Scer\GAL4^C587, vg^UAS.cKa

(Li et al., 2015)

Scer\GAL4^C587/Tgi^HMS00981 is a suppressor | partially of germarium phenotype of Scer\GAL4^C587, ci^{RNAi.UASp.cLa}

(Li et al., 2015)

Additional Comments

Genetic Interactions

Statement

Reference

The female sterility due to tumorous germaria induced by Scer\GAL4^C587-driven expression of yki^{dsRNA.shRNA.Scer\UAS.P\T} is rescued by co-expression of Tgi^HMS00981 - the double knock-down females are fertile and without significant germaria defects.

The tumorous germaria phenotype induced by Scer\GAL4^C587-driven expression of vg^Scer\UAS.cKa is partially rescued by co-expression of Tgi^HMS00981.

The rather moderate tumorous germarium phenotype characteristic for adult female flies expressing ci^{dsRNA.shRNA.Scer\UAS.P\T} under the control of Scer\GAL4^C587 is significantly improved by co-expression of Tgi^HMS00981.

(Li et al., 2015)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

34394

y¹ sc^* v¹ sev²¹; P{TRiP.HMS00981}attP2

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

CG10741^HMS00981

Tgi^HMS00981

Name Synonyms

Secondary FlyBase IDs

References (4)

Report Sections

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