FlyBase Allele Report: Dmel\Sxl[KK116156]

General Information

Symbol

Dmel\Sxl^KK116156

Species

D. melanogaster

Name

FlyBase ID

FBal0260231

Feature type

allele

Associated gene

Dmel\Sxl

Associated Insertion(s)

Carried in Construct

P{KK116156}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

(Keleman et al., 2009.8.5)

Progenitor genotype

Carried in construct

P{KK116156}

Cytology

Description

UASt regulatory sequences drive expression of an inverted repeat.

(Keleman et al., 2009.8.5)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

dsRNA-KK116156

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

Under control conditions, the adulthood-only expression of Sxl^KK116156 under the control of Scer\GAL4^esg-NP7397 (and Gal80[ts], for the temporal regulation of expression) does not significantly affect the overall mitotic index in the female and male adult posterior midgut, as compared to controls. expression in clones under the control of Scer\GAL4^tub.PU does not significantly affect the average number of clone cells in the female or male adult posterior midgut, as compared to control clones.

(Hudry et al., 2016)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhancer of

Statement

Reference

Scer\GAL4^NP7397, Sxl^KK116156, Apc2^N175K, Apc2^N175K, Apc^Q8, Apc^Q8 is a non-enhancer of increased occurrence of cell division | adult stage | somatic clone phenotype of Ras85D^V12.UAS, Scer\GAL4^NP7397

(Hudry et al., 2016)

Suppressor of

Statement

Reference

Sxl^KK116156, Scer\GAL4^NP7397 is a suppressor of increased occurrence of cell division | somatic clone | female limited | adult stage phenotype of N^GD14477, Scer\GAL4^NP7397

(Hudry et al., 2016)

Phenotype Manifest In

NOT Enhancer of

Statement

Reference

Scer\GAL4^NP7397, Sxl^KK116156, Apc2^N175K, Apc2^N175K, Apc^Q8, Apc^Q8 is a non-enhancer of adult posterior midgut epithelium | somatic clone phenotype of Ras85D^V12.UAS, Scer\GAL4^NP7397

(Hudry et al., 2016)

Suppressor of

Statement

Reference

Sxl^KK116156, Scer\GAL4^NP7397 is a suppressor of adult posterior midgut epithelium | somatic clone | female limited phenotype of N^GD14477, Scer\GAL4^NP7397

(Hudry et al., 2016)

Additional Comments

Genetic Interactions

Statement

Reference

Under control conditions, the adulthood-only co-expression of Sxl^KK116156 and msl-2^GL00309 under the control of Scer\GAL4^esg-NP7397 (and Gal80[ts], for the temporal regulation of expression) does not significantly affect the overall mitotic index in the female adult posterior midgut, as compared to controls.

The co-expression of Sxl^KK116156 suppresses the increased mitotic index in the female adult posterior midgut induced by the adulthood-only expression of N^GD14477 under the control of Scer\GAL4^esg-NP7397 (and Gal80[ts], for the temporal regulation of expression).

The clonal expression of Sxl^KK116156 in combination with clonal Apc2^N175K, Apc^Q8 double homozygosity does not enhance the increased mitotic index in the adult posterior midgut induced by the clonal expression of Ras85D^V12.UAS under the control of Scer\GAL4^esg-NP7397.

(Hudry et al., 2016)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

VDRC

v109221

P{KK116156}VIE-260B

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Sxl^KK116156

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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