FlyBase Allele Report: Dmel\Zyx[NIG.32018R]

General Information

Symbol

Dmel\Zyx^NIG.32018R

Species

D. melanogaster

Name

FlyBase ID

FBal0261091

Feature type

allele

Associated gene

Dmel\Zyx

Associated Insertion(s)

Carried in Construct

P{NIG.32018R}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Rauskolb et al., 2011)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Rauskolb et al., 2011)

Mutagen

in vitro construct

(Rauskolb et al., 2011)

Progenitor genotype

Carried in construct

P{NIG.32018R}

Cytology

Description

UASt drives expression of an RNAi construct targeting Zyx.

(Rauskolb et al., 2011)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

dsRNA-32018R

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal size, with Scer\GAL4^nub-AC-62

(Rauskolb et al., 2011)

Phenotype Manifest In

crossvein | ectopic, with Scer\GAL4^nub-AC-62

(Rauskolb et al., 2011)

wing, with Scer\GAL4^nub-AC-62

(Rauskolb et al., 2011)

Detailed Description

Statement

Reference

Expression of Zyx102EF^NIG.32018R (together with Dcr-2^Scer\UAS.cDa) using Scer\GAL4^nub-AC-62 results in adult flies with small wings. These wings sometimes have extra crossveins, though the anterior and posterior crossveins remain well separated.

(Rauskolb et al., 2011)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Scer\GAL4^nub-AC-62, Zyx^NIG.32018R has abnormal size phenotype, enhanceable by Scer\GAL4^nub-AC-62/jub^GD7185

(Rauskolb et al., 2011)

Enhancer of

Statement

Reference

Zyx^NIG.32018R/Scer\GAL4^nub-AC-62 is an enhancer of abnormal size phenotype of Scer\GAL4^nub-AC-62, jub^GD7185

(Rauskolb et al., 2011)

Zyx^NIG.32018R/Scer\GAL4^nub-AC-62 is an enhancer of abnormal size phenotype of dachs^GC13

(Rauskolb et al., 2011)

Suppressor of

Statement

Reference

Zyx^NIG.32018R/Scer\GAL4^nub-AC-62 is a suppressor of abnormal size phenotype of Scer\GAL4^nub-AC-62, dco^{3.UAS.Tag:V5,Tag:polyHis}

(Rauskolb et al., 2011)

Zyx^NIG.32018R/Scer\GAL4^nub-AC-62 is a suppressor of abnormal size phenotype of Scer\GAL4^nub-AC-62, ds^GD14350

(Rauskolb et al., 2011)

Zyx^NIG.32018R/Scer\GAL4^nub-AC-62 is a suppressor of abnormal size phenotype of Scer\GAL4^nub-AC-62, ft^GD881

(Rauskolb et al., 2011)

Zyx^NIG.32018R/Scer\GAL4^nub-AC-62 is a suppressor of abnormal size phenotype of Scer\GAL4^nub-AC-62, dachs^{UAS.Tag:V5,Tag:polyHis}

(Rauskolb et al., 2011)

Zyx^NIG.32018R/Scer\GAL4^nub-AC-62 is a suppressor | partially of abnormal size phenotype of Scer\GAL4^nub-AC-62, ex^GD12782

(Rauskolb et al., 2011)

Phenotype Manifest In

Enhanced by

Statement

Reference

Scer\GAL4^nub-AC-62, Zyx^NIG.32018R has wing phenotype, enhanceable by Scer\GAL4^nub-AC-62/jub^GD7185

(Rauskolb et al., 2011)

Enhancer of

Statement

Reference

Zyx^NIG.32018R/Scer\GAL4^nub-AC-62 is an enhancer of wing phenotype of Scer\GAL4^nub-AC-62, jub^GD7185

(Rauskolb et al., 2011)

Zyx^NIG.32018R/Scer\GAL4^nub-AC-62 is an enhancer of wing phenotype of dachs^GC13

(Rauskolb et al., 2011)

Suppressor of

Statement

Reference

Zyx^NIG.32018R/Scer\GAL4^nub-AC-62 is a suppressor of wing phenotype of Scer\GAL4^nub-AC-62, ds^GD14350

(Rauskolb et al., 2011)

Zyx^NIG.32018R/Scer\GAL4^nub-AC-62 is a suppressor of wing phenotype of Scer\GAL4^nub-AC-62, ft^GD881

(Rauskolb et al., 2011)

Zyx^NIG.32018R/Scer\GAL4^nub-AC-62 is a suppressor of wing phenotype of Scer\GAL4^nub-AC-62, dachs^{UAS.Tag:V5,Tag:polyHis}

(Rauskolb et al., 2011)

Zyx^NIG.32018R/Scer\GAL4^nub-AC-62 is a suppressor | partially of wing phenotype of Scer\GAL4^nub-AC-62, ex^GD12782

(Rauskolb et al., 2011)

Zyx^NIG.32018R/Scer\GAL4^nub-AC-62 is a suppressor of wing phenotype of Scer\GAL4^nub-AC-62, dco^{3.UAS.Tag:V5,Tag:polyHis}

(Rauskolb et al., 2011)

NOT Suppressor of

Statement

Reference

Zyx^NIG.32018R/Scer\GAL4^nub-AC-62 is a non-suppressor of crossvein phenotype of Scer\GAL4^nub-AC-62, ft^GD881

(Rauskolb et al., 2011)

Additional Comments

Genetic Interactions

Statement

Reference

The wing overgrowth phenotype associated with Scer\GAL4^nub-AC-62-mediated expression of ft^GD881 (together with Dcr-2^Scer\UAS.cDa) is suppressed by co-expression of Zyx102EF^NIG.32018R, resulting in wings of similar size to those of animals that only express Zyx102EF^NIG.32018R. However, the influence of ft^GD881 expression on crossvein spacing is not suppressed by Zyx102EF^NIG.32018R expression.

The wing overgrowth phenotype associated with Scer\GAL4^nub-AC-62-mediated expression of ds^GD14350 (together with Dcr-2^Scer\UAS.cDa) is suppressed by co-expression of Zyx102EF^NIG.32018R.

The wing overgrowth phenotype associated with Scer\GAL4^nub-AC-62-mediated expression of ex^GD12782 (together with Dcr-2^Scer\UAS.cDa) is partially suppressed by co-expression of Zyx102EF^NIG.32018R.

The wing overgrowth phenotype associated with Scer\GAL4^nub-AC-62-mediated expression of dco^{3.Scer\UAS.T:SV5\V5,T:Zzzz\His6} (together with Dcr-2^Scer\UAS.cDa) is suppressed by co-expression of Zyx102EF^NIG.32018R.

The wing overgrowth phenotype associated with Scer\GAL4^nub-AC-62-mediated expression of d^{Scer\UAS.T:SV5\V5,T:Zzzz\His6} (together with Dcr-2^Scer\UAS.cDa) is suppressed by co-expression of Zyx102EF^NIG.32018R.

Scer\GAL4^nub-AC-62-mediated expression of Zyx102EF^NIG.32018R (together with Dcr-2^Scer\UAS.cDa) enhances the small wing phenotype of d^GC13 flies.

Expression of both jub^GD7185 and Zyx102EF^NIG.32018R (together with Dcr-2^Scer\UAS.cDa) using Scer\GAL4^nub-AC-62 induces a greater reduction in wing size than when either is expressed individually.

(Rauskolb et al., 2011)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

NIG-Fly

32018R-1

P{NIG.32018R}1

32018R-3

P{NIG.32018R}3

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Zyx102EF^NIG.32018R

Zyx^NIG.32018R

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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