FlyBase Allele Report: Scer\GAL4[Pdf.Switch1a]

General Information

Symbol

Scer\GAL4^Pdf.Switch1a

Species

S. cerevisiae

Name

FlyBase ID

FBal0267534

Feature type

allele

Associated gene

Scer\GAL4

Associated Insertion(s)

Carried in Construct

P{Pdf-GS}

Also Known As

pdf-GS, pdfGS, Pdf-geneswitch, pdf-GS-Gal4

Transgenic product class

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

Mutagen

in vitro construct

(Depetris-Chauvin et al., 2011)

Progenitor genotype

Carried in construct

P{Pdf-GS}

Cytology

Description

A 2,367 bp fragment containing the Pdf promoter region regulates expression of a ligand-inducible GAL4::GS driver.

(Depetris-Chauvin et al., 2011)

Allele components

Component

Use(s)

Regulatory region(s)

Pdf

Encoded product / tool

GAL4::GS

binary expression system - small molecule-regulated driver

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

distribution deduced from reporter (Gal4 UAS)

Stage

Tissue/Position (including subcellular localization)

Reference

adult stage

LNv neuron

(Frenkel et al., 2017)

Additional Information

Statement

Reference

ScerGAL4^Pdf.Switch1a drives mifepristone-inducible expression in LNv neurons.

(Frenkel et al., 2017)

Marker for

Reflects expression of

Pdf

(Frenkel et al., 2017)

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal circadian rhythm | adult stage, with CngA^JF02039, CngA^KK108314

(Herrero et al., 2020)

abnormal circadian rhythm | adult stage, with Pdf^GD299

(Herrero et al., 2020)

abnormal circadian rhythm | adult stage, with Pdf^JF01820

(Herrero et al., 2020)

abnormal circadian rhythm | adult stage, with TrpA1^UAS.(B).cKa

(Herrero et al., 2020)

abnormal circadian rhythm | adult stage | RU486 conditional, with GlyT^GD3564

(Frenkel et al., 2017)

abnormal circadian rhythm | adult stage | RU486 conditional, with GlyT^NIG.5549R

(Frenkel et al., 2017)

abnormal circadian rhythm | adult stage | RU486 conditional, with Shmt^NIG.3011R

(Frenkel et al., 2017)

abnormal locomotor behavior | RU486 conditional, with Dop1R1^HM04077

(Fernandez-Chiappe et al., 2020)

abnormal locomotor behavior | RU486 conditional, with Dop1R2^JF02043

(Fernandez-Chiappe et al., 2020)

abnormal locomotor rhythm | adult stage, with Srrm1^KK108396

(Beckwith et al., 2017)

abnormal locomotor rhythm | adult stage | RU486 conditional, with mir-276a^UAS.pLUC

(Chen and Rosbash, 2016)

abnormal locomotor rhythm | RU486 conditional, with Hsap\KCNJ2^UAS.EGFP

(Depetris-Chauvin et al., 2011)

abnormal neuroanatomy | adult stage, with CngA^JF02039, CngA^KK108314

(Herrero et al., 2020)

abnormal neuroanatomy | adult stage, with Pdf^GD299

(Herrero et al., 2020)

abnormal neuroanatomy | adult stage, with Pdf^JF01820

(Herrero et al., 2020)

abnormal neuroanatomy | adult stage, with TrpA1^UAS.(B).cKa

(Herrero et al., 2020)

abnormal neuroanatomy | RU486 conditional, with Hsap\KCNJ2^UAS.EGFP

(Depetris-Chauvin et al., 2011)

abnormal neurophysiology | RU486 conditional, with Hsap\KCNJ2^UAS.EGFP

(Depetris-Chauvin et al., 2011)

decreased sleep | RU486 conditional, with Dop1R1^HM04077

(Fernandez-Chiappe et al., 2020)

decreased sleep | RU486 conditional, with Dop1R2^JF02043

(Fernandez-Chiappe et al., 2020)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

Scer\GAL4^Pdf.Switch1a, mir-276a^UAS.pLUC has abnormal locomotor rhythm | adult stage | RU486 conditional phenotype, suppressible | partially by tim^UAS.cYa/Scer\GAL4^Pdf.Switch1a

(Chen and Rosbash, 2016)

NOT Enhancer of

Statement

Reference

TrpA1^UAS.(B).cKa/Scer\GAL4^Pdf.Switch1a is a non-enhancer of abnormal neuroanatomy | adult stage phenotype of Pdf⁰¹

(Herrero et al., 2020)

TrpA1^UAS.(B).cKa/Scer\GAL4^Pdf.Switch1a is a non-enhancer of abnormal circadian rhythm | adult stage phenotype of Pdf⁰¹

(Herrero et al., 2020)

TrpA1^UAS.(B).cKa/Scer\GAL4^Pdf.Switch1a is a non-enhancer of abnormal neuroanatomy | adult stage phenotype of Pdfr⁵³⁰⁴

(Herrero et al., 2020)

TrpA1^UAS.(B).cKa/Scer\GAL4^Pdf.Switch1a is a non-enhancer of abnormal circadian rhythm | adult stage phenotype of Pdfr⁵³⁰⁴

(Herrero et al., 2020)

Suppressor of

Statement

Reference

tim^UAS.cYa/Scer\GAL4^Pdf.Switch1a is a suppressor | partially of abnormal locomotor rhythm | adult stage | RU486 conditional phenotype of Scer\GAL4^Pdf.Switch1a, mir-276a^UAS.pLUC

(Chen and Rosbash, 2016)

NOT Suppressor of

Statement

Reference

TrpA1^UAS.(B).cKa/Scer\GAL4^Pdf.Switch1a is a non-suppressor of abnormal neuroanatomy | adult stage phenotype of Pdf⁰¹

(Herrero et al., 2020)

TrpA1^UAS.(B).cKa/Scer\GAL4^Pdf.Switch1a is a non-suppressor of abnormal circadian rhythm | adult stage phenotype of Pdf⁰¹

(Herrero et al., 2020)

TrpA1^UAS.(B).cKa/Scer\GAL4^Pdf.Switch1a is a non-suppressor of abnormal neuroanatomy | adult stage phenotype of Pdfr⁵³⁰⁴

(Herrero et al., 2020)

TrpA1^UAS.(B).cKa/Scer\GAL4^Pdf.Switch1a is a non-suppressor of abnormal circadian rhythm | adult stage phenotype of Pdfr⁵³⁰⁴

(Herrero et al., 2020)

Phenotype Manifest In

NOT Enhancer of

Statement

Reference

TrpA1^UAS.(B).cKa/Scer\GAL4^Pdf.Switch1a is a non-enhancer of adult s-LNv neuron | adult stage phenotype of Pdf⁰¹

(Herrero et al., 2020)

TrpA1^UAS.(B).cKa/Scer\GAL4^Pdf.Switch1a is a non-enhancer of adult s-LNv neuron | adult stage phenotype of Pdfr⁵³⁰⁴

(Herrero et al., 2020)

NOT Suppressor of

Statement

Reference

TrpA1^UAS.(B).cKa/Scer\GAL4^Pdf.Switch1a is a non-suppressor of adult s-LNv neuron | adult stage phenotype of Pdf⁰¹

(Herrero et al., 2020)

TrpA1^UAS.(B).cKa/Scer\GAL4^Pdf.Switch1a is a non-suppressor of adult s-LNv neuron | adult stage phenotype of Pdfr⁵³⁰⁴

(Herrero et al., 2020)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

Bloomington

81116

w¹¹¹⁸; P{Pdf-GS}2/CyO

80956

w^*; P{UAS-mCD8::GFP.L}LL5; P{Pdf-GS}3/TM3, Sb¹

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Scer\GAL4^Pdf.Switch1a

pdfGS

(Frenkel et al., 2017)

Name Synonyms

Secondary FlyBase IDs

References (17)

Report Sections

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