FlyBase Allele Report: Scer\GAL4[G0431]

General Information

Symbol

Scer\GAL4^G0431

Species

S. cerevisiae

Name

FlyBase ID

FBal0268130

Feature type

allele

Associated gene

Scer\GAL4

Associated Insertion(s)

P{GAL4}G0431

Carried in Construct

Also Known As

G0431, G0431-gal4

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Progenitor genotype

Associated Insertion(s)

P{GAL4}G0431

Cytology

Description

Allele components

Component

Use(s)

Inserted element

P{GAL4}

enhancer trap

Encoded product / tool

GAL4

binary expression system - driver

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

distribution deduced from reporter (Gal4 UAS)

Stage

Tissue/Position (including subcellular localization)

Reference

adult stage

neuron | subset of adult brain

(Chen et al., 2012)

neuron of the dorsal anterior lateral group of the protocerebrum

(Chen et al., 2012)

calyx of adult mushroom body

(Chen et al., 2012)

Additional Information

Statement

Reference

ScerGAL4^G0431 labels the dorsal anterior lateral (DAL) neurons of the protocerebrum, among others. Using GFP reconstitution across synaptic partners (GRASP) reveals that these DAL neurons establish connections in the mushroom body calyx K5 region with the pioneer alpha/beta neurons of the mushroom body, labeled by EcollexA^L5275.

(Chen et al., 2012)

Marker for

neuron of the dorsal anterior lateral group of the protocerebrum

(Chen et al., 2012)

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal memory, with CaMKII^RNAi.UAS

(Chen et al., 2012)

abnormal memory, with CrebB^b.UAS

(Chen et al., 2012)

abnormal memory, with CrebB^KK108927

(Chen et al., 2012)

abnormal memory, with per^RNAi.PAS.UAS

(Chen et al., 2012)

abnormal memory, with Rcom\RT^A-cs2.UAS

(Chen et al., 2012)

abnormal memory, with teq^RNAi.UAS

(Chen et al., 2012)

abnormal memory | heat sensitive, with shi^1.UAS

(Chen et al., 2012)

Phenotype Manifest In

Detailed Description

Statement

Reference

Blocking synaptic transmission (using shi^1.Scer\UAS at restrictive temperatures) from Scer\GAL4^G0431 neurons does not significantly impair sucrose-reinforced appetitive memory performance (24 hours since training) compared to controls. Flies undergo conditioning at a permissive temperature (23[o]C), whereas testing is at a restrictive temperature (33[o]C).

(Perisse et al., 2013)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Scer\GAL4^G0431

Name Synonyms

Secondary FlyBase IDs

References (8)

Report Sections

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