FlyBase Allele Report: Scer\GAL4[egr-GAL4]

General Information

Symbol

Scer\GAL4^egr-GAL4

Species

S. cerevisiae

Name

FlyBase ID

FBal0269193

Feature type

allele

Associated gene

Scer\GAL4

Associated Insertion(s)

P{GAL4}egr^GAL4

Carried in Construct

Also Known As

Egr-Gal4

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Keller et al., 2011)

Progenitor genotype

Associated Insertion(s)

P{GAL4}egr^GAL4

Cytology

Description

The P{GAL4} is inserted 21bp upstream of the egr transcription start site.

(Keller et al., 2011)

Allele components

Component

Use(s)

Inserted element

P{GAL4}

enhancer trap

Encoded product / tool

GAL4

binary expression system - driver

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

distribution deduced from reporter (Gal4 UAS)

Stage

Tissue/Position (including subcellular localization)

Reference

third instar larval stage

embryonic/larval wrapping glial cell | subset

(Keller et al., 2011)

Additional Information

Statement

Reference

Marker for

Reflects expression of

egr

(Keller et al., 2011)

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal locomotor behavior | adult stage, with Acox1^N250S.UAS

(Chung et al., 2020)

abnormal neurophysiology | larval stage, with Ada2b^JF01305

(Wang et al., 2020)

abnormal neurophysiology | larval stage, with Gcn5^KK101976

(Wang et al., 2020)

abnormal neurophysiology | larval stage, with Mp^JF02929

(Wang et al., 2020)

abnormal neurophysiology | larval stage, with not^JF03152

(Wang et al., 2020)

abnormal neurophysiology | larval stage, with Sar1^KK108654

(Wang et al., 2020)

partially lethal, with Acox1^N250S.UAS

(Chung et al., 2020)

short lived, with Acox1^N250S.UAS

(Chung et al., 2020)

Phenotype Manifest In

embryonic/larval neuromuscular junction | larval stage, with Ada2b^JF01305

(Wang et al., 2020)

embryonic/larval neuromuscular junction | larval stage, with Gcn5^KK101976

(Wang et al., 2020)

embryonic/larval neuromuscular junction | larval stage, with Mp^JF02929

(Wang et al., 2020)

embryonic/larval neuromuscular junction | larval stage, with not^JF03152

(Wang et al., 2020)

embryonic/larval neuromuscular junction | larval stage, with Sar1^KK108654

(Wang et al., 2020)

embryonic/larval perineurial glial cell | larval stage, with Sar1^KK108654

(Wang et al., 2020)

larval abdominal segment, with Ada2b^JF01305

(Wang et al., 2020)

larval abdominal segment, with Sar1^KK108654

(Wang et al., 2020)

NMJ bouton | increased number | larval stage, with Ada2b^JF01305

(Wang et al., 2020)

NMJ bouton | increased number | larval stage, with Sar1^KK108654

(Wang et al., 2020)

presynaptic active zone | increased number | larval stage, with Ada2b^JF01305

(Wang et al., 2020)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

Acox1^N250S.UAS, Scer\GAL4^egr-GAL4 has short lived phenotype, suppressible by Cat^UAS.cAa, Scer\GAL4^egr-GAL4

(Chung et al., 2020)

Acox1^N250S.UAS, Scer\GAL4^egr-GAL4 has abnormal locomotor behavior | adult stage phenotype, suppressible by Cat^UAS.cAa, Scer\GAL4^egr-GAL4

(Chung et al., 2020)

Suppressor of

Statement

Reference

Cat^UAS.cAa, Scer\GAL4^egr-GAL4 is a suppressor of short lived phenotype of Acox1^N250S.UAS, Scer\GAL4^egr-GAL4

(Chung et al., 2020)

Cat^UAS.cAa, Scer\GAL4^egr-GAL4 is a suppressor of abnormal locomotor behavior | adult stage phenotype of Acox1^N250S.UAS, Scer\GAL4^egr-GAL4

(Chung et al., 2020)

egr^RNAi.UAS/Scer\GAL4^egr-GAL4 is a suppressor | partially of abnormal neuroanatomy phenotype of Ank2^f02001

(Keller et al., 2011)

NOT Suppressor of

Statement

Reference

Mp^{ES.UAS.Tag:SS(wg)}/Scer\GAL4^egr-GAL4 is a non-suppressor of abnormal neurophysiology | larval stage phenotype of Ada2b¹

(Wang et al., 2020)

Phenotype Manifest In

Suppressor of

Statement

Reference

egr^RNAi.UAS/Scer\GAL4^egr-GAL4 is a suppressor | partially of embryonic/larval neuromuscular junction | third instar larval stage phenotype of Ank2^f02001

(Keller et al., 2011)

NOT Suppressor of

Statement

Reference

Mp^{ES.UAS.Tag:SS(wg)}/Scer\GAL4^egr-GAL4 is a non-suppressor of embryonic/larval neuromuscular junction | larval stage phenotype of Ada2b¹

(Wang et al., 2020)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

Ada2b^{UAS.ORF.GW.Tag:HA}/Scer\GAL4^egr-GAL4 rescues Ada2b¹

(Wang et al., 2020)

Mp^3hNC1.UAS/Scer\GAL4^egr-GAL4 rescues Mp^f07253

(Wang et al., 2020)

Mp^{ES.UAS.Tag:SS(wg)}/Scer\GAL4^egr-GAL4 rescues Mp^f07253

(Wang et al., 2020)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Scer\GAL4^egr-GAL4

Name Synonyms

Secondary FlyBase IDs

References (7)

Report Sections