FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\ruUAS.EGFP
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General Information
Symbol
Dmel\ruUAS.EGFP
Species
D. melanogaster
Name
FlyBase ID
FBal0276764
Feature type
allele
Associated gene
Dmel\ru
Associated Insertion(s)
Carried in Construct
P{UAS-ru.eGFP}
Key Links
Transgenic product class
wild_type
(Yogev et al., 2010)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Yogev et al., 2010)
Mutagen
in vitro construct
(Yogev et al., 2010)
Progenitor genotype
Carried in construct
P{UAS-ru.eGFP}
Cytology
Description

UASt regulatory sequences drive expression of ru tagged with EGFP.

(Yogev et al., 2010)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
ru
Tagged with
EGFP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      ruUAS.EGFP/Scer\GAL4GMR.PF is a suppressor | partially of eye phenotype of Rab11S25N.UAS

      (Yogev et al., 2010)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Expression of ruScer\UAS.T:Avic\GFP-EGFP partially rescues the small, rough eyes seen when Rab11S25N.Scer\UAS is expressed under the control of Scer\GAL4GMR.PF.

      (Yogev et al., 2010)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      ruUAS.EGFP/Scer\GAL4GMR.PF rescues ruPLLb

      (Yogev et al., 2010)

      ruUAS.EGFP/Scer\GAL4MT14 rescues ruPLLb

      (Yogev et al., 2010)
      Partially rescues

      ruUAS.EGFP/Scer\GAL4lz-gal4 partially rescues ruPLLb

      (Yogev et al., 2010)
      Fails to rescue

      ruUAS.EGFP/Scer\GAL4hs.2sev fails to rescue ruPLLb

      (Yogev et al., 2010)

      ruUAS.EGFP/Scer\GAL4sca-537.4 fails to rescue ruPLLb

      (Yogev et al., 2010)
      Comments

      Expression of ruScer\UAS.T:Avic\GFP-EGFP in all photoreceptors (R1 - R8) under the control of Scer\GAL4GMR.PF fully rescues the lamina cartridge neuron differentiation defects seen in the eye discs of ruPLLb mutant third instar larvae.

      Expression of ruScer\UAS.T:Avic\GFP-EGFP in the R2, R5 and R8 photoreceptors under the control of Scer\GAL4MT14 fully rescues the lamina cartridge neuron differentiation defects seen in the eye discs of ruPLLb mutant third instar larvae.

      Expression of ruScer\UAS.T:Avic\GFP-EGFP in the R1, R6 and R7 photoreceptors under the control of Scer\GAL4lz-gal4 partially rescues the lamina cartridge neuron differentiation defects seen in the eye discs of ruPLLb mutant third instar larvae. 20% of the wild type number of lamina cells express differentiation markers.

      Expression of ruScer\UAS.T:Avic\GFP-EGFP in the R3, R4 and R7 photoreceptors under the control of Scer\GAL4hs.2sev fails to rescue the lamina cartridge neuron differentiation defects seen in the eye discs of ruPLLb mutant third instar larvae.

      Expression of ruScer\UAS.T:Avic\GFP-EGFP in the R4 and weakly in the R3 photoreceptors under the control of Scer\GAL4hs.2sev fails to rescue the lamina cartridge neuron differentiation defects seen in the eye discs of ruPLLb mutant third instar larvae.

      Expression of ruScer\UAS.T:Avic\GFP-EGFP in the R8 photoreceptors under the control of Scer\GAL4sca-537.4 fails to rescue the lamina cartridge neuron differentiation defects seen in the eye discs of ruPLLb mutant third instar larvae.

      (Yogev et al., 2010)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      ruScer\UAS.T:Avic\GFP-EGFP
      ruUAS.EGFP
      Name Synonyms
      Secondary FlyBase IDs
        References (1)