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General Information
Symbol
Dmel\dsxUAS.female
Species
D. melanogaster
Name
FlyBase ID
FBal0283667
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-dsxF
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UASt regulatory sequences drive expression of the female specific isoform of dsx.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expression of dsxUAS.female under the control of Scer\GAL4insc-Mz1407 from mid second instar stage, in combination with a Gal80[ts] transgene, results in a reduced number of neuroblasts in the thoracic segments of the late third instar male larval ventral nerve cord, compared to controls; expression in females from early first instar stage does not prevent female-specific loss of larval terminal neuroblasts, compared to controls.

Under control conditions, the adulthood-only expression of dsxUAS.female under the control of Scer\GAL4esg-NP7397 (together with Gal80[ts], for the temporal regulation of expression, and Dicer-2, for efficient RNAi) does not significantly affect the number of progenitor cells (intestinal stem cells/enteroblasts) or the mitotic index in the female or male adult posterior midgut, as compared to controls.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

Expression of Abd-BGD4680 and dsxUAS.female, in combination with a Dicer-2 transgene to enhance RNAi efficiency, under the control of Scer\GAL4insc-Mz1407 from early first instar stage, in combination with a Gal80[ts] transgene, prevents female-specific loss of larval terminal neuroblasts, compared to controls; there is also a significant decrease in the number of thoracic neuroblasts in the female, compared to controls.

Under control conditions, the adulthood-only co-expression of dsxUAS.female and traJF03132 under the control of Scer\GAL4esg-NP7397 (together with Gal80[ts], for the temporal regulation of expression, and Dicer-2, for efficient RNAi) does not significantly affect the number of progenitor cells (intestinal stem cells/enteroblasts) or the mitotic index in the female adult posterior midgut, as compared to controls.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
dsxF.Scer\UAS
dsxScer\UAS.female
dsxUAS.female
Name Synonyms
Secondary FlyBase IDs
  • FBal0122995
  • FBal0282761
References (10)