FlyBase Allele Report: Dmel\mir-33[KO]

General Information

Symbol

Dmel\mir-33^KO

Species

D. melanogaster

Name

FlyBase ID

FBal0301926

Feature type

allele

Associated gene

Dmel\mir-33

Associated Insertion(s)

TI{TI}mir-33^KO

Carried in Construct

Key Links

Allele class

amorphic allele - molecular evidence

Mutagen

Nature of the Allele

Allele class

amorphic allele - molecular evidence

(Chen et al., 2014)

Mutagen

ends-out gene targeting

(Chen et al., 2014)

FLPase

(Chen et al., 2014)

I-SceI

(Chen et al., 2014)

cre recombinase

(Chen et al., 2014)

Progenitor genotype

Associated Insertion(s)

TI{TI}mir-33^KO

Cytology

Description

The mir-33 hairpin has been deleted. A single loxP site is present at the site of the deletion. It is not known whether or not expression of the host SREBP gene is affected.

(Chen et al., 2014)

Allele components

Component

Use(s)

Also carries

loxP

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal neuroanatomy | embryonic stage

(Wang et al., 2026)

abnormal neuroanatomy | larval stage

(Wang et al., 2026)

decreased rate of larval locomotory behavior

(Wang et al., 2026)

female fertile

(Chen et al., 2014)

increased size | larval stage

(Wang et al., 2026)

male fertile

(Chen et al., 2014)

Phenotype Manifest In

axon | embryonic stage

(Wang et al., 2026)

commissure | embryonic stage

(Wang et al., 2026)

connective | embryonic stage

(Wang et al., 2026)

embryonic/larval neuromuscular junction | larval stage

(Wang et al., 2026)

NMJ bouton | increased number | larval stage

(Wang et al., 2026)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

mir-33^KO has abnormal neuroanatomy | embryonic stage phenotype, suppressible by Scer\GAL4^elav.PU/Hsap\MIR33A^UAS.cWa

(Wang et al., 2026)

mir-33^KO has abnormal neuroanatomy | larval stage phenotype, suppressible by Scer\GAL4^elav.PU/Hsap\MIR33A^UAS.cWa

(Wang et al., 2026)

mir-33^KO has increased size | larval stage phenotype, suppressible by Scer\GAL4^elav.PU/Hsap\MIR33A^UAS.cWa

(Wang et al., 2026)

mir-33^KO has abnormal neuroanatomy | embryonic stage phenotype, suppressible | partially by trio¹

(Wang et al., 2026)

mir-33^KO has abnormal neuroanatomy | embryonic stage phenotype, suppressible by Scer\GAL4^elav.PU/trio^GD9531

(Wang et al., 2026)

mir-33^KO has abnormal neuroanatomy | larval stage phenotype, suppressible by trio¹

(Wang et al., 2026)

mir-33^KO has abnormal neuroanatomy | larval stage phenotype, suppressible by Scer\GAL4^elav.PU/trio^GD9531

(Wang et al., 2026)

mir-33^KO has increased size | larval stage phenotype, suppressible by trio¹

(Wang et al., 2026)

mir-33^KO has increased size | larval stage phenotype, suppressible by Scer\GAL4^elav.PU/trio^GD9531

(Wang et al., 2026)

Suppressor of

Statement

Reference

mir-33^KO is a suppressor | partially of abnormal neuroanatomy | dominant | embryonic stage phenotype of trio¹

(Wang et al., 2026)

mir-33^KO is a suppressor of abnormal neuroanatomy | dominant | larval stage phenotype of trio¹

(Wang et al., 2026)

mir-33^KO is a suppressor of abnormal neuroanatomy | larval stage phenotype of Scer\GAL4^elav.PU, trio^GD9531

(Wang et al., 2026)

mir-33^KO is a suppressor of decreased size | larval stage phenotype of Scer\GAL4^elav.PU, trio^GD9531

(Wang et al., 2026)

mir-33^KO is a suppressor of abnormal neuroanatomy | embryonic stage phenotype of Scer\GAL4^elav.PU, trio^GD9531

(Wang et al., 2026)

mir-33^KO is a suppressor of decreased size | dominant | larval stage phenotype of trio¹

(Wang et al., 2026)

mir-33^KO is a suppressor of abnormal neuroanatomy | embryonic stage phenotype of Hsap\MIR33A^UAS.cWa, Scer\GAL4^elav.PU

(Wang et al., 2026)

mir-33^KO is a suppressor of abnormal neuroanatomy | larval stage phenotype of Hsap\MIR33A^UAS.cWa, Scer\GAL4^elav.PU

(Wang et al., 2026)

mir-33^KO is a suppressor of decreased size | larval stage phenotype of Hsap\MIR33A^UAS.cWa, Scer\GAL4^elav.PU

(Wang et al., 2026)

Phenotype Manifest In

Suppressed by

Statement

Reference

mir-33^KO has axon | embryonic stage phenotype, suppressible | partially by trio¹

(Wang et al., 2026)

mir-33^KO has connective | embryonic stage phenotype, suppressible | partially by trio¹

(Wang et al., 2026)

mir-33^KO has commissure | embryonic stage phenotype, suppressible by trio¹

(Wang et al., 2026)

mir-33^KO has axon | embryonic stage phenotype, suppressible by Scer\GAL4^elav.PU/trio^GD9531

(Wang et al., 2026)

mir-33^KO has connective | embryonic stage phenotype, suppressible by Scer\GAL4^elav.PU/trio^GD9531

(Wang et al., 2026)

mir-33^KO has commissure | embryonic stage phenotype, suppressible by Scer\GAL4^elav.PU/trio^GD9531

(Wang et al., 2026)

mir-33^KO has embryonic/larval neuromuscular junction | larval stage phenotype, suppressible by trio¹

(Wang et al., 2026)

mir-33^KO has embryonic/larval neuromuscular junction | larval stage phenotype, suppressible by Scer\GAL4^elav.PU/trio^GD9531

(Wang et al., 2026)

mir-33^KO has NMJ bouton | increased number | larval stage phenotype, suppressible by trio¹

(Wang et al., 2026)

mir-33^KO has NMJ bouton | increased number | larval stage phenotype, suppressible by Scer\GAL4^elav.PU/trio^GD9531

(Wang et al., 2026)

mir-33^KO has axon | embryonic stage phenotype, suppressible by Scer\GAL4^elav.PU/Hsap\MIR33A^UAS.cWa

(Wang et al., 2026)

mir-33^KO has connective | embryonic stage phenotype, suppressible by Scer\GAL4^elav.PU/Hsap\MIR33A^UAS.cWa

(Wang et al., 2026)

mir-33^KO has commissure | embryonic stage phenotype, suppressible by Scer\GAL4^elav.PU/Hsap\MIR33A^UAS.cWa

(Wang et al., 2026)

mir-33^KO has embryonic/larval neuromuscular junction | larval stage phenotype, suppressible by Scer\GAL4^elav.PU/Hsap\MIR33A^UAS.cWa

(Wang et al., 2026)

mir-33^KO has NMJ bouton | increased number | larval stage phenotype, suppressible by Scer\GAL4^elav.PU/Hsap\MIR33A^UAS.cWa

(Wang et al., 2026)

Suppressor of

Statement

Reference

mir-33^KO is a suppressor of axon | embryonic stage phenotype of Scer\GAL4^elav.PU, trio^GD9531

(Wang et al., 2026)

mir-33^KO is a suppressor of connective | embryonic stage phenotype of Scer\GAL4^elav.PU, trio^GD9531

(Wang et al., 2026)

mir-33^KO is a suppressor of commissure | embryonic stage phenotype of Scer\GAL4^elav.PU, trio^GD9531

(Wang et al., 2026)

mir-33^KO is a suppressor | partially of axon | embryonic stage phenotype of trio¹

(Wang et al., 2026)

mir-33^KO is a suppressor | partially of connective | embryonic stage phenotype of trio¹

(Wang et al., 2026)

mir-33^KO is a suppressor of commissure | embryonic stage phenotype of Hsap\MIR33A^UAS.cWa, Scer\GAL4^elav.PU

(Wang et al., 2026)

mir-33^KO is a suppressor of connective | embryonic stage phenotype of Hsap\MIR33A^UAS.cWa, Scer\GAL4^elav.PU

(Wang et al., 2026)

mir-33^KO is a suppressor of axon | embryonic stage phenotype of Hsap\MIR33A^UAS.cWa, Scer\GAL4^elav.PU

(Wang et al., 2026)

mir-33^KO is a suppressor of NMJ bouton | larval stage | decreased number phenotype of Hsap\MIR33A^UAS.cWa, Scer\GAL4^elav.PU

(Wang et al., 2026)

mir-33^KO is a suppressor of embryonic/larval neuromuscular junction | larval stage phenotype of Hsap\MIR33A^UAS.cWa, Scer\GAL4^elav.PU

(Wang et al., 2026)

mir-33^KO is a suppressor of commissure | embryonic stage phenotype of trio¹

(Wang et al., 2026)

mir-33^KO is a suppressor of NMJ bouton | larval stage | decreased number phenotype of trio¹

(Wang et al., 2026)

mir-33^KO is a suppressor of embryonic/larval neuromuscular junction | larval stage phenotype of trio¹

(Wang et al., 2026)

mir-33^KO is a suppressor of embryonic/larval neuromuscular junction | larval stage phenotype of Scer\GAL4^elav.PU, trio^GD9531

(Wang et al., 2026)

mir-33^KO is a suppressor of NMJ bouton | larval stage | decreased number phenotype of Scer\GAL4^elav.PU, trio^GD9531

(Wang et al., 2026)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescued by

mir-33^KO is rescued by Scer\GAL4^elav.PU/mir-33^UAS.cSb

(Wang et al., 2026)

Rescues

Scer\GAL4^elav.PU/mir-33^KO rescues mir-33^UAS.cSb

(Wang et al., 2026)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

miR-33^KO

(Wang et al., 2026, Clerbaux et al., 2021)

mir-33^KO

(Niu et al., 2019)

Name Synonyms

Secondary FlyBase IDs

References (5)

Report Sections

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