FlyBase Allele Report: Dmel\mir-33[UAS.cSb]

General Information

Symbol

Dmel\mir-33^UAS.cSb

Species

D. melanogaster

Name

Saccharomyces cerevisiae UAS construct b of Szuplewski

FlyBase ID

FBal0304030

Feature type

allele

Associated gene

Dmel\mir-33

Associated Insertion(s)

Carried in Construct

P{UAS-mir-33.S}

Also Known As

UAS-miR-33

Key Links

Transgenic product class

wild_type

(Szuplewski et al., 2012)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Szuplewski et al., 2012)

Mutagen

in vitro construct

(Szuplewski et al., 2012)

Progenitor genotype

Carried in construct

P{UAS-mir-33.S}

Cytology

Description

UAS regulatory sequences drive expression of a genomic fragment containing the mir-33 miRNA stem loop plus approximately 100bp upstream and downstream.

(Szuplewski et al., 2012)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

mir-33

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal neuroanatomy | embryonic stage, with Scer\GAL4^elav.PU

(Wang et al., 2026)

abnormal neuroanatomy | larval stage, with Scer\GAL4^elav.PU

(Wang et al., 2026)

decreased rate of larval locomotory behavior, with Scer\GAL4^elav.PU

(Wang et al., 2026)

decreased size | larval stage, with Scer\GAL4^elav.PU

(Wang et al., 2026)

Phenotype Manifest In

axon | embryonic stage, with Scer\GAL4^elav.PU

(Wang et al., 2026)

commissure | embryonic stage, with Scer\GAL4^elav.PU

(Wang et al., 2026)

connective | embryonic stage, with Scer\GAL4^elav.PU

(Wang et al., 2026)

embryonic/larval neuromuscular junction | larval stage, with Scer\GAL4^elav.PU

(Wang et al., 2026)

NMJ bouton | decreased number | larval stage, with Scer\GAL4^elav.PU

(Wang et al., 2026)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

Scer\GAL4^elav.PU, mir-33^UAS.cSb has abnormal neuroanatomy | embryonic stage phenotype, suppressible by Scer\GAL4^elav.PU/trio^UAS.cBa

(Wang et al., 2026)

Scer\GAL4^elav.PU, mir-33^UAS.cSb has abnormal neuroanatomy | larval stage phenotype, suppressible by Scer\GAL4^elav.PU/trio^UAS.cBa

(Wang et al., 2026)

Scer\GAL4^elav.PU, mir-33^UAS.cSb has decreased size | larval stage phenotype, suppressible by Scer\GAL4^elav.PU/trio^UAS.cBa

(Wang et al., 2026)

Scer\GAL4^elav.PU, mir-33^UAS.cSb has abnormal neuroanatomy | embryonic stage phenotype, suppressible by E2f1ⁱ²/E2f1⁰⁷¹⁷²

(Wang et al., 2026)

Scer\GAL4^elav.PU, mir-33^UAS.cSb has abnormal neuroanatomy | larval stage phenotype, suppressible by E2f1ⁱ²/E2f1⁰⁷¹⁷²

(Wang et al., 2026)

Scer\GAL4^elav.PU, mir-33^UAS.cSb has decreased size | larval stage phenotype, suppressible by E2f1ⁱ²/E2f1⁰⁷¹⁷²

(Wang et al., 2026)

Scer\GAL4^elav.PU, mir-33^UAS.cSb has abnormal neuroanatomy | embryonic stage phenotype, suppressible | partially by Hsap\TRIO^UAS.Tag:V5, Scer\GAL4^elav.PU

(Wang et al., 2026)

Scer\GAL4^elav.PU, mir-33^UAS.cSb has abnormal neuroanatomy | larval stage phenotype, suppressible by Hsap\TRIO^UAS.Tag:V5, Scer\GAL4^elav.PU

(Wang et al., 2026)

Scer\GAL4^elav.PU, mir-33^UAS.cSb has decreased size | larval stage phenotype, suppressible by Hsap\TRIO^UAS.Tag:V5, Scer\GAL4^elav.PU

(Wang et al., 2026)

Suppressor of

Statement

Reference

Scer\GAL4^elav.PU/mir-33^UAS.cSb is a suppressor of abnormal neuroanatomy | larval stage phenotype of Scer\GAL4^elav.PU, trio^UAS.cBa

(Wang et al., 2026)

Scer\GAL4^elav.PU/mir-33^UAS.cSb is a suppressor of increased size | larval stage phenotype of Scer\GAL4^elav.PU, trio^UAS.cBa

(Wang et al., 2026)

Scer\GAL4^elav.PU/mir-33^UAS.cSb is a suppressor of abnormal neuroanatomy | embryonic stage phenotype of Scer\GAL4^elav.PU, trio^UAS.cBa

(Wang et al., 2026)

Scer\GAL4^elav.PU/mir-33^UAS.cSb is a suppressor of abnormal neuroanatomy | embryonic stage phenotype of E2f1ⁱ²/E2f1⁰⁷¹⁷²

(Wang et al., 2026)

Scer\GAL4^elav.PU/mir-33^UAS.cSb is a suppressor of abnormal neuroanatomy | larval stage phenotype of E2f1ⁱ²/E2f1⁰⁷¹⁷²

(Wang et al., 2026)

Scer\GAL4^elav.PU/mir-33^UAS.cSb is a suppressor of increased size | larval stage phenotype of E2f1ⁱ²/E2f1⁰⁷¹⁷²

(Wang et al., 2026)

mir-33^UAS.cSb, Scer\GAL4^elav.PU is a suppressor | partially of abnormal neuroanatomy | embryonic stage phenotype of Hsap\TRIO^UAS.Tag:V5, Scer\GAL4^elav.PU

(Wang et al., 2026)

mir-33^UAS.cSb, Scer\GAL4^elav.PU is a suppressor of abnormal neuroanatomy | larval stage phenotype of Hsap\TRIO^UAS.Tag:V5, Scer\GAL4^elav.PU

(Wang et al., 2026)

mir-33^UAS.cSb, Scer\GAL4^elav.PU is a suppressor of increased size | larval stage phenotype of Hsap\TRIO^UAS.Tag:V5, Scer\GAL4^elav.PU

(Wang et al., 2026)

NOT Suppressor of

Statement

Reference

Scer\GAL4^sca.PU/mir-33^UAS.cSb is a non-suppressor of visible phenotype of Scer\GAL4^sca.PU, mi^GD11624

(Szuplewski et al., 2012)

Phenotype Manifest In

Suppressed by

Statement

Reference

Scer\GAL4^elav.PU, mir-33^UAS.cSb has connective | embryonic stage phenotype, suppressible | partially by Hsap\TRIO^UAS.Tag:V5, Scer\GAL4^elav.PU

(Wang et al., 2026)

Scer\GAL4^elav.PU, mir-33^UAS.cSb has axon | embryonic stage phenotype, suppressible | partially by Hsap\TRIO^UAS.Tag:V5, Scer\GAL4^elav.PU

(Wang et al., 2026)

Scer\GAL4^elav.PU, mir-33^UAS.cSb has commissure | embryonic stage phenotype, suppressible by Hsap\TRIO^UAS.Tag:V5, Scer\GAL4^elav.PU

(Wang et al., 2026)

Scer\GAL4^elav.PU, mir-33^UAS.cSb has embryonic/larval neuromuscular junction | larval stage phenotype, suppressible by Hsap\TRIO^UAS.Tag:V5, Scer\GAL4^elav.PU

(Wang et al., 2026)

Scer\GAL4^elav.PU, mir-33^UAS.cSb has NMJ bouton | larval stage | decreased number phenotype, suppressible by Hsap\TRIO^UAS.Tag:V5, Scer\GAL4^elav.PU

(Wang et al., 2026)

Scer\GAL4^elav.PU, mir-33^UAS.cSb has connective | embryonic stage phenotype, suppressible by Scer\GAL4^elav.PU/trio^UAS.cBa

(Wang et al., 2026)

Scer\GAL4^elav.PU, mir-33^UAS.cSb has axon | embryonic stage phenotype, suppressible by Scer\GAL4^elav.PU/trio^UAS.cBa

(Wang et al., 2026)

Scer\GAL4^elav.PU, mir-33^UAS.cSb has commissure | embryonic stage phenotype, suppressible by Scer\GAL4^elav.PU/trio^UAS.cBa

(Wang et al., 2026)

Scer\GAL4^elav.PU, mir-33^UAS.cSb has NMJ bouton | larval stage | decreased number phenotype, suppressible by Scer\GAL4^elav.PU/trio^UAS.cBa

(Wang et al., 2026)

Scer\GAL4^elav.PU, mir-33^UAS.cSb has embryonic/larval neuromuscular junction | larval stage phenotype, suppressible by Scer\GAL4^elav.PU/trio^UAS.cBa

(Wang et al., 2026)

Scer\GAL4^elav.PU, mir-33^UAS.cSb has connective | embryonic stage phenotype, suppressible by E2f1ⁱ²/E2f1⁰⁷¹⁷²

(Wang et al., 2026)

Scer\GAL4^elav.PU, mir-33^UAS.cSb has axon | embryonic stage phenotype, suppressible by E2f1ⁱ²/E2f1⁰⁷¹⁷²

(Wang et al., 2026)

Scer\GAL4^elav.PU, mir-33^UAS.cSb has commissure | embryonic stage phenotype, suppressible by E2f1ⁱ²/E2f1⁰⁷¹⁷²

(Wang et al., 2026)

Scer\GAL4^elav.PU, mir-33^UAS.cSb has NMJ bouton | larval stage | decreased number phenotype, suppressible by E2f1ⁱ²/E2f1⁰⁷¹⁷²

(Wang et al., 2026)

Scer\GAL4^elav.PU, mir-33^UAS.cSb has embryonic/larval neuromuscular junction | larval stage phenotype, suppressible by E2f1ⁱ²/E2f1⁰⁷¹⁷²

(Wang et al., 2026)

Suppressor of

Statement

Reference

Scer\GAL4^elav.PU/mir-33^UAS.cSb is a suppressor of NMJ bouton | increased number | larval stage phenotype of Scer\GAL4^elav.PU, trio^UAS.cBa

(Wang et al., 2026)

Scer\GAL4^elav.PU/mir-33^UAS.cSb is a suppressor of embryonic/larval neuromuscular junction | larval stage phenotype of Scer\GAL4^elav.PU, trio^UAS.cBa

(Wang et al., 2026)

Scer\GAL4^elav.PU/mir-33^UAS.cSb is a suppressor of axon | embryonic stage phenotype of Scer\GAL4^elav.PU, trio^UAS.cBa

(Wang et al., 2026)

Scer\GAL4^elav.PU/mir-33^UAS.cSb is a suppressor of connective | embryonic stage phenotype of Scer\GAL4^elav.PU, trio^UAS.cBa

(Wang et al., 2026)

Scer\GAL4^elav.PU/mir-33^UAS.cSb is a suppressor of commissure | embryonic stage phenotype of Scer\GAL4^elav.PU, trio^UAS.cBa

(Wang et al., 2026)

mir-33^UAS.cSb, Scer\GAL4^elav.PU is a suppressor | partially of connective | embryonic stage phenotype of Hsap\TRIO^UAS.Tag:V5, Scer\GAL4^elav.PU

(Wang et al., 2026)

mir-33^UAS.cSb, Scer\GAL4^elav.PU is a suppressor | partially of axon | embryonic stage phenotype of Hsap\TRIO^UAS.Tag:V5, Scer\GAL4^elav.PU

(Wang et al., 2026)

mir-33^UAS.cSb, Scer\GAL4^elav.PU is a suppressor of commissure | embryonic stage phenotype of Hsap\TRIO^UAS.Tag:V5, Scer\GAL4^elav.PU

(Wang et al., 2026)

mir-33^UAS.cSb, Scer\GAL4^elav.PU is a suppressor of embryonic/larval neuromuscular junction | larval stage phenotype of Hsap\TRIO^UAS.Tag:V5, Scer\GAL4^elav.PU

(Wang et al., 2026)

mir-33^UAS.cSb, Scer\GAL4^elav.PU is a suppressor of NMJ bouton | increased number | larval stage phenotype of Hsap\TRIO^UAS.Tag:V5, Scer\GAL4^elav.PU

(Wang et al., 2026)

Scer\GAL4^elav.PU/mir-33^UAS.cSb is a suppressor of commissure | embryonic stage phenotype of E2f1ⁱ²/E2f1⁰⁷¹⁷²

(Wang et al., 2026)

Scer\GAL4^elav.PU/mir-33^UAS.cSb is a suppressor of connective | embryonic stage phenotype of E2f1ⁱ²/E2f1⁰⁷¹⁷²

(Wang et al., 2026)

Scer\GAL4^elav.PU/mir-33^UAS.cSb is a suppressor of axon | embryonic stage phenotype of E2f1ⁱ²/E2f1⁰⁷¹⁷²

(Wang et al., 2026)

Scer\GAL4^elav.PU/mir-33^UAS.cSb is a suppressor of NMJ bouton | increased number | larval stage phenotype of E2f1ⁱ²/E2f1⁰⁷¹⁷²

(Wang et al., 2026)

Scer\GAL4^elav.PU/mir-33^UAS.cSb is a suppressor of embryonic/larval neuromuscular junction | larval stage phenotype of E2f1ⁱ²/E2f1⁰⁷¹⁷²

(Wang et al., 2026)

NOT Suppressor of

Statement

Reference

Scer\GAL4^sca.PU/mir-33^UAS.cSb is a non-suppressor of macrochaeta phenotype of Scer\GAL4^sca.PU, mi^GD11624

(Szuplewski et al., 2012)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescued by

mir-33^UAS.cSb is rescued by Scer\GAL4^elav.PU/mir-33^KO

(Wang et al., 2026)

Rescues

Scer\GAL4^elav.PU/mir-33^UAS.cSb rescues mir-33^KO

(Wang et al., 2026)

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

Bloomington

59872

w^*; P{UAS-mir-33.S}attP2

59871

w^*; P{UAS-mir-33.S}attP16

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

mir-33^Scer\UAS.cSb

mir-33^UAS.cSb

Name Synonyms

Saccharomyces cerevisiae UAS construct b of Szuplewski

Secondary FlyBase IDs

References (4)

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