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General Information
Symbol
Dmel\upd3x21b
Species
D. melanogaster
Name
FlyBase ID
FBal0302831
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

There is a insertion upstream of upd3, about 100bp further toward the 5' end of upd3 than the progenitor insertion.

Insertion components
P{XP}upd3x21b
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

The eyes of upd3x21b mutant flies are reduced in size compared to controls. The number of ommatidia is reduced, but most remaining facets appear normal. Missing ommatidia appear to be replaced by head cuticle, resulting in increased bare cuticle between the bristles surrounding the eye and the ommatidia.

upd3d232a/upd3x21b mutant flies have outstretched wings and small eyes compared to wild type.

Df(1)os1/upd3x21b mutant flies have outstretched wings and small eyes compared to wild type.

upd3x21b/Df(1)os1A2 mutant flies have outstretched wings and small eyes compared to wild type.

upd3x21b/Df(1)oso mutant flies have outstretched wings. Eye size is similar to wild type.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhanced by
Statement
Reference

upd3x21b has visible phenotype, enhanceable by Stat92E397/Stat92E[+]

upd3x21b has visible phenotype, enhanceable by Stat92E85C9/Stat92E[+]

NOT Enhanced by
Statement
Reference

upd3x21b has visible phenotype, non-enhanceable by Stat92E397/Stat92E[+]

upd3x21b has visible phenotype, non-enhanceable by Stat92E85C9/Stat92E[+]

NOT suppressed by
Statement
Reference

upd3x21b has visible phenotype, non-suppressible by Socs36E[+]/Socs36E189a

Phenotype Manifest In
NOT Enhanced by
Statement
Reference

upd3x21b has eye phenotype, non-enhanceable by Stat92E397/Stat92E[+]

upd3x21b has eye phenotype, non-enhanceable by Stat92E85C9/Stat92E[+]

NOT suppressed by
Statement
Reference

upd3x21b has eye phenotype, non-suppressible by Socs36E[+]/Socs36E189a

Other
Statement
Reference

Stat92E397/Stat92E[+], upd3x21b has wing phenotype

Stat92E397/Stat92E[+], upd3x21b has haltere phenotype

Stat92E85C9/Stat92E[+], upd3x21b has wing phenotype

Stat92E85C9/Stat92E[+], upd3x21b has haltere phenotype

Additional Comments
Genetic Interactions
Statement
Reference

Stat92E397 does not significantly enhances the reduction in eye size seen in upd3x21b mutant flies.

Stat92E397 produces outstretched wing and held down haltere phenotypes in upd3x21b mutant flies.

Stat92E85C9 does not significantly enhance the reduction in eye size seen in upd3x21b mutant flies.

Stat92E85C9 produces outstretched wing and held down haltere phenotypes in upd3x21b mutant flies.

One copy of Socs36E189a has no effect on eye size in upd3x21b mutant flies.

One copy of Socs36E189a does not produce outstretched wing or held out haltere phenotypes seen in upd3x21b mutant flies.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Not rescued by
Comments

Expression of upd3t13 is unable to rescue the eye and wing phenotypes seen in upd3x21b mutant flies.

Expression of upd3Scer\UAS.T:Avic\GFP under the control of Scer\GAL4upd3.PA rescues the reduction in eye size seen in upd3x21b mutant males.

Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
    References (1)