FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Scer\GAL4Ilp2.215-1
Open Close
General Information
Symbol
Scer\GAL4Ilp2.215-1
Species
S. cerevisiae
Name
FlyBase ID
FBal0305188
Feature type
allele
Associated gene
Scer\GAL4
Associated Insertion(s)
Carried in Construct
P{Ilp215-1-GAL4}
Also Known As
dilp2-GAL4, Ilp215-1-GAL4
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Park et al., 2014)
Progenitor genotype
Carried in construct
P{Ilp215-1-GAL4}
Cytology
Description

The 541bp sequence upstream of the Ilp2 transcription start site regulates expression of a GAL4 driver.

(Park et al., 2014)
Allele components
Component
Use(s)
Encoded product / tool
GAL4
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter (Gal4 UAS)
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      wandering third instar larval stage
      larval insulin secreting cell of pars intercerebralis
      (Buhler et al., 2018)
      adult stage
      adult insulin secreting cell of pars intercerebralis
      (Palu and Thummel, 2016, Alfa et al., 2015, Park et al., 2014)
      Additional Information
      Statement
      Reference

      ScerGAL4Ilp2.215-1 drives expression in insulin producing cells.

      (Alfa et al., 2015)

      ScerGAL4Ilp2.215-1 drives adult expression exclusively in insulin secreting cells in the medial pars intercerebralis.

      (Park et al., 2014)
       
      Marker for
      Reflects expression of
      Ilp2
      (Buhler et al., 2018, Palu and Thummel, 2016, Alfa et al., 2015, Park et al., 2014)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Increasing the excitability of Insulin Producing Cells via Scer\GAL4Ilp2.215-1-mediated expression of Bhal\NaChBacScer\UAS.cNa results in increased triglyceride stores in adult flies compared to controls.

      (Alfa et al., 2015)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Scer\GAL4Ilp2.215-1
      Name Synonyms
      Secondary FlyBase IDs
        References (9)