FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Dlish4506
Open Close
General Information
Symbol
Dmel\Dlish4506
Species
D. melanogaster
Name
FlyBase ID
FBal0323150
Feature type
allele
Associated gene
Dmel\Dlish
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
CRISPR/Cas9
(Zhang et al., 2016)
Progenitor genotype
Cytology
Description

Deletion ( 2L:17723434..17723971 ) that extends from just 5' to the Dlish open reading frame and deletes sequence coding for amino acids 1-62.

(Zhang et al., 2016)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
deletion
2R:17,723,434..17,723,971 [+]
Comment:

The deletion ( 2L:17723434..17723971 ) extends from just 5' to the Dlish open reading frame to the end of the codon for amino acids 62.

(Zhang et al., 2016)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Dlish4506 homozygous show multiple defects in the wing: reduced crossvein spacing as well as mild proximal hair polarity defects.

      (Zhang et al., 2016)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressor of
      NOT Suppressor of
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The overgrowth of the posterior wing compartment observed in adults expressing dScer\UAS.T:SV5\V5,T:Zzzz\His6 under the control of Scer\GAL4hh.PU is fully suppressed by combination with Dlish4506 in homozygous state, in contrast, the overgrowth induced by expression of dScer\UAS.T:Uuuu\CAAX-Unk,T:Ivir\HA1 cannot be suppressed by combination with Dlish4506.

      (Zhang et al., 2016)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Dlish4506
      dlish4506
      (Wang et al., 2019, Zhang et al., 2016)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)