FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Scer\GAL4Gr2a-GAL4
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General Information
Symbol
Scer\GAL4Gr2a-GAL4
Species
S. cerevisiae
Name
FlyBase ID
FBal0327037
Feature type
allele
Associated gene
Scer\GAL4
Associated Insertion(s)
TI{GAL4}Gr2aGAL4
Carried in Construct
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ends-out gene targeting
(Kim et al., 2017)
Progenitor genotype
Associated Insertion(s)
TI{GAL4}Gr2aGAL4
Cytology
Description

Part of the first exon of Gr2a is replaced by sequence encoding a GAL4 driver and a w+* marker; this allows expression of GAL4 under the control of endogenous Gr2a regulatory sequences.

(Kim et al., 2017)
Allele components
Component
Use(s)
Inserted element
TI{GAL4}
Encoded product / tool
GAL4
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter (Gal4 UAS)
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      adult stage
      high salt/bitter-sensing neuron | subset of adult labral sense organ
      (Kim et al., 2017)
      adult subesophageal zone | dorsal | restricted
      (Kim et al., 2017)
      Additional Information
      Statement
      Reference

      ScerGAL4Gr2a-GAL4 drives expression in a single pair of L2 GRNs in the adult labral sense organ that are maintained during the transition from larva (where they are known as gustatory receptor neurons of the epiphysis) to adult. These neurons send axonal projections in an umbrella like pattern to the left and right dorsal regions of the subesophageal zone.

      (Kim et al., 2017)
       
      Marker for
      Reflects expression of
      Gr2a
      (Kim et al., 2017)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Gr2aGAL4
      (Kim et al., 2017)
      Scer\GAL4Gr2a-GAL4
      Name Synonyms
      Secondary FlyBase IDs
        References (1)