FlyBase Allele Report: Dmel\Glyat[TH00482]

General Information

Symbol

Dmel\Glyat^TH00482

Species

D. melanogaster

Name

FlyBase ID

FBal0327509

Feature type

allele

Associated gene

Dmel\Glyat

Associated Insertion(s)

Carried in Construct

P{TRiP.TH00482}

Key Links

Transgenic product class

RNAi_reagent

(Ren et al., 2017)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Ren et al., 2017)

Mutagen

in vitro construct

(Ren et al., 2017)

Progenitor genotype

Carried in construct

P{TRiP.TH00482}

Cytology

Description

UAS regulatory sequences drive expression of a short inverted repeat.

(Ren et al., 2017)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

Glyat

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

ameliorates carcinoma

modeled by scrib^RNAi.UAS.cUa

(Xu et al., 2022)

modeled by egr^GS9830

(Xu et al., 2022)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

Glyat^TH00482, Scer\GAL4^GMR.PU is a suppressor | partially of abnormal size | adult stage phenotype of Scer\GAL4^GMR.PU, hep^CA.UAS

(Ren et al., 2017)

Glyat^TH00482, Scer\GAL4^GMR.PU is a suppressor | partially of visible | adult stage phenotype of Scer\GAL4^GMR.PU, hep^CA.UAS

(Ren et al., 2017)

Glyat^TH00482, Scer\GAL4^GMR.PU is a suppressor | partially of increased cell death | third instar larval stage phenotype of Scer\GAL4^GMR.PU, hep^CA.UAS

(Ren et al., 2017)

Glyat^TH00482, Scer\GAL4^ptc-559.1 is a suppressor | partially of increased cell death | third instar larval stage phenotype of Scer\GAL4^ptc-559.1, hep^CA.UAS

(Ren et al., 2017)

Glyat^TH00482, Scer\GAL4^ptc-559.1 is a suppressor | partially of increased cell death | third instar larval stage phenotype of Scer\GAL4^ptc-559.1, puc^GD1515

(Ren et al., 2017)

Glyat^TH00482, Scer\GAL4^ptc-559.1 is a suppressor | partially of increased cell death | third instar larval stage phenotype of Scer\GAL4^ptc-559.1, l(2)gl^GD4047

(Ren et al., 2017)

Glyat^TH00482, Scer\GAL4^GMR.PU is a suppressor | partially of abnormal size | adult stage phenotype of Scer\GAL4^GMR.PU, egr^GS9830

(Ren et al., 2017)

Glyat^TH00482, Scer\GAL4^GMR.PU is a suppressor | partially of visible | adult stage phenotype of Scer\GAL4^GMR.PU, egr^GS9830

(Ren et al., 2017)

Glyat^TH00482, Scer\GAL4^GMR.PU is a suppressor | partially of increased cell death | third instar larval stage phenotype of Scer\GAL4^GMR.PU, egr^GS9830

(Ren et al., 2017)

Glyat^TH00482, Scer\GAL4^ptc-559.1 is a suppressor | partially of increased cell death | third instar larval stage phenotype of Scer\GAL4^ptc-559.1, egr^GS9830

(Ren et al., 2017)

NOT Suppressor of

Statement

Reference

Glyat^TH00482, Scer\GAL4^GMR.PU is a non-suppressor of abnormal size | adult stage phenotype of Scer\GAL4^GMR.PU, p53^UAS.Ex

(Ren et al., 2017)

Glyat^TH00482, Scer\GAL4^GMR.PU is a non-suppressor of visible | adult stage phenotype of Scer\GAL4^GMR.PU, p53^UAS.Ex

(Ren et al., 2017)

Phenotype Manifest In

Suppressor of

Statement

Reference

Glyat^TH00482, Scer\GAL4^ptc-559.1 is a suppressor | partially of anterior crossvein | third instar larval stage phenotype of Scer\GAL4^ptc-559.1, egr^GS9830

(Ren et al., 2017)

Glyat^TH00482, Scer\GAL4^GMR.PU is a suppressor | partially of eye phenotype of Scer\GAL4^GMR.PU, hep^CA.UAS

(Ren et al., 2017)

Glyat^TH00482, Scer\GAL4^GMR.PU is a suppressor | partially of eye disc morphogenetic furrow | third instar larval stage phenotype of Scer\GAL4^GMR.PU, hep^CA.UAS

(Ren et al., 2017)

Glyat^TH00482, Scer\GAL4^ptc-559.1 is a suppressor | partially of anterior-posterior compartment boundary of the wing disc | third instar larval stage phenotype of Scer\GAL4^ptc-559.1, hep^CA.UAS

(Ren et al., 2017)

Glyat^TH00482, Scer\GAL4^ptc-559.1 is a suppressor | partially of anterior crossvein | third instar larval stage phenotype of Scer\GAL4^ptc-559.1, hep^CA.UAS

(Ren et al., 2017)

Glyat^TH00482, Scer\GAL4^ptc-559.1 is a suppressor | partially of anterior-posterior compartment boundary of the wing disc | third instar larval stage phenotype of Scer\GAL4^ptc-559.1, puc^GD1515

(Ren et al., 2017)

Glyat^TH00482, Scer\GAL4^ptc-559.1 is a suppressor | partially of anterior-posterior compartment boundary of the wing disc | third instar larval stage phenotype of Scer\GAL4^ptc-559.1, l(2)gl^GD4047

(Ren et al., 2017)

Glyat^TH00482, Scer\GAL4^GMR.PU is a suppressor | partially of eye phenotype of Scer\GAL4^GMR.PU, egr^GS9830

(Ren et al., 2017)

Glyat^TH00482, Scer\GAL4^GMR.PU is a suppressor | partially of eye disc morphogenetic furrow | third instar larval stage phenotype of Scer\GAL4^GMR.PU, egr^GS9830

(Ren et al., 2017)

Glyat^TH00482, Scer\GAL4^ptc-559.1 is a suppressor | partially of anterior-posterior compartment boundary of the wing disc | third instar larval stage phenotype of Scer\GAL4^ptc-559.1, egr^GS9830

(Ren et al., 2017)

NOT Suppressor of

Statement

Reference

Glyat^TH00482, Scer\GAL4^GMR.PU is a non-suppressor of eye phenotype of Scer\GAL4^GMR.PU, p53^UAS.Ex

(Ren et al., 2017)

Additional Comments

Genetic Interactions

Statement

Reference

The co-expression of Glyat^TH00482 partially suppresses the eye-related phenotypes (i.e. increased apoptosis at the morphogenetic furrow of the third instar larval eye disc and the decreased eye size in adults) and the wing-related phenotypes (i.e. increased apoptosis around the anterior-posterior compartment boundary of the third instar larval wing disc and the highly penetrant anterior crossvein loss in the adult wing) resulting from the expression of egr^GS9830 or hep^CA.Scer\UAS under the control of Scer\GAL4^GMR.PU (eye phenotypes) or Scer\GAL4^ptc-559.1 (wing phenotypes) and partially suppresses the increased apoptosis around the anterior-posterior compartment boundary of the third instar larval wing disc resulting from the expression of either puc^GD1515 or l(2)gl^GD4047 under the control of Scer\GAL4^ptc-559.1, but does not suppress the small eye phenotype resulting from the expression of p53^Scer\UAS.Ex under the control of Scer\GAL4^GMR.PU.

(Ren et al., 2017)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Glyat^TH00482

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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