Open Close
General Information
Symbol
Dmel\Dh44-R2174
Species
D. melanogaster
Name
FlyBase ID
FBal0327572
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Mutagen
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Comment:

A 5 bp deletion in the 6th exon of Dh44-R2 leads to a frameshift resulting in a truncated protein.

Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

5bp deletion in exon 6 of Dh44-R2; the frameshift mutation is predicted to result in a non-functional truncated protein with only two transmembrane domains.

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Dh44-R2174 homozygous adults have similar period length, but significantly reduced strength of circadian locomotor rhythms under constant darkness, compared to heterozygous controls.

Dh44-R2174/Df(2R)BSC305 adults also have significantly reduced strength of circadian locomotor rhythms under constant darkness, compared to heterozygous controls; there is no difference in their activity profile under light-dark or dark-dark conditions, compared to controls.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
NOT Enhancer of
Statement
Reference
NOT Suppressor of
Statement
Reference
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
    References (2)