FlyBase Allele Report: Dmel\Xbp1[UAS.s.Tag:V5]

General Information

Symbol

Dmel\Xbp1^UAS.s.Tag:V5

Species

D. melanogaster

Name

FlyBase ID

FBal0356306

Feature type

allele

Associated gene

Dmel\Xbp1

Associated Insertion(s)

Carried in Construct

P{UAS-Xbp1.s.V5}

Also Known As

UAS-Xbp1s

Key Links

Transgenic product class

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

Mutagen

in vitro construct

(Yan et al., 2019)

Progenitor genotype

Carried in construct

P{UAS-Xbp1.s.V5}

Cytology

Description

UAS regulatory sequences drive expression of a cDNA that encodes the active spliced form of Xbp1. The coding sequence is tagged with Tag:V5.

(Yan et al., 2019)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

Xbp1

Tagged with

Tag:V5

epitope tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

ameliorates cancer

modeled by Ras85D^V12.cUa.UAS, l(2)gl⁴

(Yang et al., 2022)

modeled by Ras85D^V12.cUa.UAS, scrib¹

(Yang et al., 2022)

modeled by Raf^UAS.F179, scrib¹

(Yang et al., 2022)

modeled by sav³

(Yang et al., 2022)

modeled by wts^x1

(Yang et al., 2022)

modeled by yki^UAS.cHa

(Yang et al., 2022)

modeled by wts^KK101055

(Yang et al., 2022)

modeled by scrib^GD11663

(Yang et al., 2022)

modeled by dlg1^GD4689

(Yang et al., 2022)

ameliorates carcinoma

modeled by scrib¹

(Zheng et al., 2023)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal starvation stress response | adult stage, with Scer\GAL4^Cg.PA

(Zhao et al., 2021)

decreased cell number | larval stage | somatic clone, with Scer\GAL4^Act.PU

(Zheng et al., 2023)

increased cell death | larval stage | somatic clone, with Scer\GAL4^Act.PU

(Zheng et al., 2023)

Phenotype Manifest In

eye-antennal disc | somatic clone, with Scer\GAL4^Act.PU

(Zheng et al., 2023)

Detailed Description

Statement

Reference

The expression of Xbp1^UAS.s.Tag:V5 under the control of Scer\GAL4^GMR.long does not induce any obvious eye phenotype (overall morphology, ommatidial array, interommatidial bristles), as compared to controls.

(Yan et al., 2019)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

Scer\GAL4^Act.PU, Xbp1^UAS.s.Tag:V5, scrib¹ has decreased cell number | somatic clone | larval stage phenotype, suppressible by BacA\p35^UAS.cHa, Scer\GAL4^Act.PU

(Zheng et al., 2023)

Scer\GAL4^Act.PU, Xbp1^UAS.s.Tag:V5, scrib¹ has decreased cell number | somatic clone | larval stage phenotype, suppressible | partially by bsk^DN.UAS/Scer\GAL4^Act.PU

(Zheng et al., 2023)

Enhancer of

Statement

Reference

Scer\GAL4^Act.PU/Xbp1^UAS.s.Tag:V5 is an enhancer of increased cell death | larval stage | somatic clone phenotype of scrib¹

(Zheng et al., 2023)

Scer\GAL4^Act.PU/Xbp1^UAS.s.Tag:V5 is an enhancer of decreased cell number | larval stage | somatic clone phenotype of scrib¹

(Zheng et al., 2023)

Scer\GAL4^Act.PU/Xbp1^UAS.s.Tag:V5 is an enhancer of decreased size | adult stage phenotype of Scer\GAL4^GMR.PU, egr^UAS.cIa

(Zheng et al., 2023)

Scer\GAL4^Act.PU/Xbp1^UAS.s.Tag:V5 is an enhancer of visible | adult stage phenotype of Scer\GAL4^GMR.PU, egr^UAS.cIa

(Zheng et al., 2023)

Suppressor of

Statement

Reference

Scer\GAL4^Act.PU/Xbp1^UAS.s.Tag:V5 is a suppressor | partially of melanotic necrosis | somatic clone | adult stage phenotype of scrib¹

(Zheng et al., 2023)

Scer\GAL4^Act.PU/Xbp1^UAS.s.Tag:V5 is a suppressor of decreased cell size | somatic clone | larval stage phenotype of Scer\GAL4^Act.PU, foxo^UAS.cFa

(Zhao et al., 2021)

Scer\GAL4^Act.PU/Xbp1^UAS.s.Tag:V5 is a suppressor of decreased size | somatic clone | larval stage phenotype of Scer\GAL4^Act.PU, foxo^UAS.cFa

(Zhao et al., 2021)

Xbp1^UAS.s.Tag:V5/Scer\GAL4^Cg.PA is a suppressor | partially of decreased body size | larval stage phenotype of Scer\GAL4^Cg.PA, foxo^UAS.cFa

(Zhao et al., 2021)

Xbp1^UAS.s.Tag:V5/Scer\GAL4^Cg.PA is a suppressor | partially of abnormal developmental rate phenotype of Scer\GAL4^Cg.PA, foxo^UAS.cFa

(Zhao et al., 2021)

Xbp1^UAS.s.Tag:V5, Scer\GAL4^Cg.PA is a suppressor of abnormal starvation stress response | adult stage phenotype of Ire1^GD3071, Scer\GAL4^Cg.PA

(Zhao et al., 2021)

Xbp1^UAS.s.Tag:V5, Scer\GAL4^Cg.PA is a suppressor of increased mortality | adult stage phenotype of Ire1^GD3071, Scer\GAL4^Cg.PA

(Zhao et al., 2021)

Xbp1^UAS.s.Tag:V5, Scer\GAL4^GMR.long is a suppressor | partially of visible | adult stage phenotype of Ire1^UAS.Tag:V5, Scer\GAL4^GMR.long

(Yan et al., 2019)

Xbp1^UAS.s.Tag:V5, Scer\GAL4^GMR.long is a suppressor | partially of increased cell death | third instar larval stage phenotype of Ire1^UAS.Tag:V5, Scer\GAL4^GMR.long

(Yan et al., 2019)

Other

Statement

Reference

Scer\GAL4^Act.PU, Xbp1^UAS.s.Tag:V5, scrib¹ has decreased cell number | somatic clone | larval stage phenotype

(Zheng et al., 2023)

Phenotype Manifest In

Suppressed by

Statement

Reference

Scer\GAL4^Act.PU, Xbp1^UAS.s.Tag:V5, scrib¹ has eye-antennal disc | somatic clone phenotype, suppressible by BacA\p35^UAS.cHa, Scer\GAL4^Act.PU

(Zheng et al., 2023)

Scer\GAL4^Act.PU, Xbp1^UAS.s.Tag:V5, scrib¹ has eye-antennal disc | somatic clone phenotype, suppressible | partially by bsk^DN.UAS/Scer\GAL4^Act.PU

(Zheng et al., 2023)

Enhancer of

Statement

Reference

Scer\GAL4^Act.PU/Xbp1^UAS.s.Tag:V5 is an enhancer of eye-antennal disc | somatic clone phenotype of scrib¹

(Zheng et al., 2023)

Scer\GAL4^Act.PU/Xbp1^UAS.s.Tag:V5 is an enhancer of autophagosome | larval stage | increased number | somatic clone phenotype of scrib¹

(Zheng et al., 2023)

Scer\GAL4^Act.PU/Xbp1^UAS.s.Tag:V5 is an enhancer of eye phenotype of Scer\GAL4^GMR.PU, egr^UAS.cIa

(Zheng et al., 2023)

Suppressor of

Statement

Reference

Scer\GAL4^Act.PU/Xbp1^UAS.s.Tag:V5 is a suppressor | partially of eye | somatic clone phenotype of scrib¹

(Zheng et al., 2023)

Scer\GAL4^Act.PU/Xbp1^UAS.s.Tag:V5 is a suppressor of larval fat cell | somatic clone phenotype of Scer\GAL4^Act.PU, foxo^UAS.cFa

(Zhao et al., 2021)

Scer\GAL4^Act.PU/Xbp1^UAS.s.Tag:V5 is a suppressor of lipid droplet | somatic clone | larval stage phenotype of Scer\GAL4^Act.PU, foxo^UAS.cFa

(Zhao et al., 2021)

Xbp1^UAS.s.Tag:V5, Scer\GAL4^GMR.long is a suppressor | partially of eye phenotype of Ire1^UAS.Tag:V5, Scer\GAL4^GMR.long

(Yan et al., 2019)

Xbp1^UAS.s.Tag:V5, Scer\GAL4^GMR.long is a suppressor | partially of ommatidium phenotype of Ire1^UAS.Tag:V5, Scer\GAL4^GMR.long

(Yan et al., 2019)

Xbp1^UAS.s.Tag:V5, Scer\GAL4^GMR.long is a suppressor | partially of interommatidial bristle phenotype of Ire1^UAS.Tag:V5, Scer\GAL4^GMR.long

(Yan et al., 2019)

Xbp1^UAS.s.Tag:V5, Scer\GAL4^GMR.long is a suppressor | partially of eye disc phenotype of Ire1^UAS.Tag:V5, Scer\GAL4^GMR.long

(Yan et al., 2019)

Other

Statement

Reference

Scer\GAL4^Act.PU, Xbp1^UAS.s.Tag:V5, scrib¹ has eye-antennal disc | somatic clone phenotype

(Zheng et al., 2023)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Xbp1^UAS.s.Tag:V5

Name Synonyms

Secondary FlyBase IDs

References (6)

Report Sections

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