FlyBase Allele Report: Dmel\Nmdar2[YH7]

General Information

Symbol

Dmel\Nmdar2^YH7

Species

D. melanogaster

Name

FlyBase ID

FBal0373524

Feature type

allele

Associated gene

Dmel\Nmdar2

Associated Insertion(s)

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

CRISPR/Cas9

Nature of the Allele

Allele class

Mutagen

CRISPR/Cas9

(Li et al., 2021)

Progenitor genotype

Cytology

Description

Mutation within the Nmdar2 coding sequence; results in a premature stop codon.

(Li et al., 2021)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

deletion

X:1,502,238..1,502,245 [-]

Comment:

An 8bp deletion starting in the fifth amino acid that causes a frameshift and early translation termination. There is also a 9bp deletion (TTGATCCTG - X:1502062..1502070:-1 ) beyond the early stop codon.

(Chien and Dickman, 2022.8.19, Li et al., 2021)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Suppressor of

Statement

Reference

Nmdar2^YH7/Nmdar2^YH9 is a non-suppressor of abnormal neurophysiology | larval stage phenotype of Scer\GAL4^VGlut1-OK371, VGlut1^UAS.cDa

(Li et al., 2021)

Nmdar2^YH7 is a non-suppressor of abnormal neurophysiology | larval stage phenotype of Scer\GAL4^VGlut1-OK371, VGlut1^UAS.cDa

(Li et al., 2021)

Phenotype Manifest In

NOT Suppressor of

Statement

Reference

Nmdar2^YH7/Nmdar2^YH9 is a non-suppressor of embryonic/larval neuromuscular junction phenotype of Scer\GAL4^VGlut1-OK371, VGlut1^UAS.cDa

(Li et al., 2021)

Nmdar2^YH7 is a non-suppressor of embryonic/larval neuromuscular junction phenotype of Scer\GAL4^VGlut1-OK371, VGlut1^UAS.cDa

(Li et al., 2021)

Nmdar2^YH7 is a non-suppressor of muscle cell of A1-7 ventral longitudinal muscle 3 | larval stage phenotype of Scer\GAL4^VGlut1-OK371, VGlut1^UAS.cDa

(Li et al., 2021)

Nmdar2^YH7/Nmdar2^YH9 is a non-suppressor of muscle cell of A1-7 ventral longitudinal muscle 3 | larval stage phenotype of Scer\GAL4^VGlut1-OK371, VGlut1^UAS.cDa

(Li et al., 2021)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

NMDAR2^YH7

(Perry et al., 2022, Li et al., 2021)

Nmdar2^YH7

(Chien and Dickman, 2022.8.19)

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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