FlyBase Allele Report: Dmel\Cpes[1]

General Information

Symbol

Dmel\Cpes¹

Species

D. melanogaster

Name

FlyBase ID

FBal0387700

Feature type

allele

Associated gene

Dmel\Cpes

Associated Insertion(s)

TI{TI}Cpes¹

Carried in Construct

Key Links

Allele class

amorphic allele - molecular evidence

Mutagen

CRISPR/Cas9

Nature of the Allele

Allele class

amorphic allele - molecular evidence

(Chen et al., 2022)

Mutagen

CRISPR/Cas9

(Chen et al., 2022)

Progenitor genotype

Associated Insertion(s)

TI{TI}Cpes¹

Cytology

Description

GFP coding sequence is inserted into the Cpes locus, ahead of the initiation codon site.

(Chen et al., 2022)

Allele components

Component

Use(s)

Tagged with

GFP

green fluorescent protein

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal circadian rhythm | adult stage

(Chen et al., 2022)

chemical sensitive | adult stage

(Chen et al., 2022)

increased mortality | adult stage | conditional

(Chen et al., 2022)

male sterile

(Chen et al., 2022)

short lived

(Chen et al., 2022)

visible | adult stage

(Chen et al., 2022)

Phenotype Manifest In

adult abdomen

(Chen et al., 2022)

adult brain

(Chen et al., 2022)

synapse | adult stage | decreased number

(Chen et al., 2022)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

Cpes¹ has abnormal circadian rhythm | adult stage phenotype, suppressible by nSMase¹/nSMase¹

(Chen et al., 2022)

Cpes¹ has abnormal circadian rhythm | adult stage phenotype, suppressible | partially by Scer\GAL4^repo/Hsap\SGMS1^UAS.C.Tag:V5

(Chen et al., 2022)

Cpes¹ has abnormal circadian rhythm | adult stage phenotype, suppressible | partially by Scer\GAL4^repo/Hsap\SGMS2^UAS.C.Tag:V5

(Chen et al., 2022)

NOT suppressed by

Statement

Reference

Cpes¹ has abnormal circadian rhythm | adult stage phenotype, non-suppressible by SMSr^UAS.Tag:V5/Scer\GAL4^repo

(Chen et al., 2022)

Cpes¹ has abnormal circadian rhythm | adult stage phenotype, non-suppressible by Hsap\SGMS1^{mut.UAS.C.Tag:V5}/Scer\GAL4^repo

(Chen et al., 2022)

Cpes¹ has abnormal circadian rhythm | adult stage phenotype, non-suppressible by Scer\GAL4^repo/Hsap\SAMD8^UAS.Tag:V5

(Chen et al., 2022)

Suppressor of

Statement

Reference

Cpes¹/Cpes¹ is a suppressor of abnormal circadian rhythm | adult stage phenotype of nSMase¹

(Chen et al., 2022)

Phenotype Manifest In

Suppressed by

Statement

Reference

Cpes¹ has adult brain phenotype, suppressible | partially by Scer\GAL4^repo/Hsap\SGMS1^UAS.C.Tag:V5

(Chen et al., 2022)

Cpes¹ has adult brain phenotype, suppressible | partially by Scer\GAL4^repo/Hsap\SGMS2^UAS.C.Tag:V5

(Chen et al., 2022)

NOT suppressed by

Statement

Reference

Cpes¹ has adult brain phenotype, non-suppressible by Hsap\SGMS1^{mut.UAS.C.Tag:V5}/Scer\GAL4^repo

(Chen et al., 2022)

Cpes¹ has adult brain phenotype, non-suppressible by SMSr^UAS.Tag:V5/Scer\GAL4^repo

(Chen et al., 2022)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Partially rescued by

Cpes¹ is partially rescued by Cpes^UAS.Tag:V5/Scer\GAL4^repo

(Chen et al., 2022)

Cpes¹ is partially rescued by Cpes^UAS.Tag:V5/Scer\GAL4^alrm.PD

(Chen et al., 2022)

Cpes¹ is partially rescued by Cpes^UAS.Tag:V5/Scer\GAL4^GMR86E01

(Chen et al., 2022)

Cpes¹ is partially rescued by Cpes^UAS.Tag:V5/Scer\GAL4^αTub84B.PL

(Chen et al., 2022)

Not rescued by

Cpes¹ is not rescued by Cpes^UAS.Tag:V5/Scer\GAL4^nSyb.PS

(Chen et al., 2022)

Cpes¹ is not rescued by Cpes^UAS.Tag:V5/Scer\GAL4^nrv2.PS

(Chen et al., 2022)

Cpes¹ is not rescued by Scer\GAL4^GMR53H12/Cpes^UAS.Tag:V5

(Chen et al., 2022)

Cpes¹ is not rescued by Scer\GAL4^GMR56F03/Cpes^UAS.Tag:V5

(Chen et al., 2022)

Cpes¹ is not rescued by Cpes^UAS.Tag:V5/Scer\GAL4^GMR54C07

(Chen et al., 2022)

Cpes¹ is not rescued by Cpes^UAS.Tag:V5/Scer\GAL4^GMR75H03

(Chen et al., 2022)

Cpes¹ is not rescued by Scer\GAL4^GMR54H02/Cpes^UAS.Tag:V5

(Chen et al., 2022)

Cpes¹ is not rescued by Scer\GAL4^GMR47G01/Cpes^UAS.Tag:V5

(Chen et al., 2022)

Cpes¹ is not rescued by Cpes^UAS.Tag:V5/Scer\GAL4^GMR85G01

(Chen et al., 2022)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Cpes¹

cpes¹

(Chen et al., 2022)

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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