FlyBase Allele Report: Dmel\galectin[wgv]

General Information

Symbol

Dmel\galectin^wgv

Species

D. melanogaster

Name

FlyBase ID

FBal0405392

Feature type

allele

Associated gene

Dmel\galectin

Associated Insertion(s)

TI{GAL4::VP16}galectin^wgv

Carried in Construct

Key Links

Allele class

amorphic allele - molecular evidence

Mutagen

Nature of the Allele

Allele class

amorphic allele - molecular evidence

(Sung et al., 2024)

Mutagen

CRISPR/Cas9

(Sung et al., 2024)

gene targeting by homologous recombination

(Sung et al., 2024)

Progenitor genotype

Associated Insertion(s)

TI{GAL4::VP16}galectin^wgv

Cytology

Description

Deletion that removes part of the galectin coding sequence. A sequence cassette encoding 1. the GAL4::VP16 coding sequence and 2. a loxP cassette containing a Disc\RFP^3xP3.cUa marker has been inserted in place of the deleted sequence. The inserted sequence is flanked by a pair of inverted attP sites, and can thus act as a target for recombination-mediate cassette exchange (RMCE).

(Sung et al., 2024)

Allele components

Component

Use(s)

Inserted element

TI{GAL4::VP16}

promoter trap

Encoded product / tool

GAL4::VP16

binary expression system - driver

Also carries

attP

integrase target site

loxP

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

dendrite | P-stage, with Scer\GAL4^A58

(Sung et al., 2024)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

ctg^wgd, galectin^wgv has abnormal neuroanatomy | P-stage phenotype, suppressible by galectin^+tGR

(Sung et al., 2024)

ctg^wgd, galectin^wgv has abnormal neuroanatomy | larval stage phenotype, suppressible | partially by galectin^+tGR

(Sung et al., 2024)

ctg^wgd, galectin^wgv has abnormal neuroanatomy | P-stage phenotype, suppressible by galectin^UAS.mRFP1/Scer\GAL4^Hml.PU

(Sung et al., 2024)

ctg^wgd, galectin^wgv has abnormal neuroanatomy | larval stage phenotype, suppressible by galectin^UAS.mRFP1/Scer\GAL4^Hml.PU

(Sung et al., 2024)

ctg^wgd, galectin^wgv has abnormal neuroanatomy | P-stage phenotype, suppressible by ctg^+tGR

(Sung et al., 2024)

ctg^wgd, galectin^wgv has abnormal neuroanatomy | larval stage phenotype, suppressible | partially by ctg^+tGR

(Sung et al., 2024)

ctg^wgd, galectin^wgv has abnormal neuroanatomy | P-stage phenotype, suppressible by ctg^UAS.mRFP1/Scer\GAL4^Hml.PU

(Sung et al., 2024)

ctg^wgd, galectin^wgv has abnormal neuroanatomy | larval stage phenotype, suppressible by ctg^UAS.mRFP1/Scer\GAL4^Hml.PU

(Sung et al., 2024)

NOT suppressed by

Statement

Reference

ctg^wgd, galectin^wgv has abnormal neuroanatomy | P-stage phenotype, non-suppressible by ctg^UAS.mRFP1/Scer\GAL4^ppk.PG

(Sung et al., 2024)

ctg^wgd, galectin^wgv has abnormal neuroanatomy | P-stage phenotype, non-suppressible by ctg^UAS.mRFP1/Scer\GAL4^A58

(Sung et al., 2024)

ctg^wgd, galectin^wgv has abnormal neuroanatomy | P-stage phenotype, non-suppressible by galectin^UAS.mRFP1/Scer\GAL4^ppk.PG

(Sung et al., 2024)

ctg^wgd, galectin^wgv has abnormal neuroanatomy | P-stage phenotype, non-suppressible by galectin^UAS.mRFP1/Scer\GAL4^A58

(Sung et al., 2024)

NOT Enhancer of

Statement

Reference

ctg^wgd/galectin^wgv is a non-enhancer of abnormal neuroanatomy | P-stage phenotype of drpr^Δ5

(Sung et al., 2024)

ctg^wgd/galectin^wgv is a non-enhancer of abnormal neuroanatomy | P-stage phenotype of drpr^indel

(Sung et al., 2024)

Suppressor of

Statement

Reference

ctg^wgd/galectin^wgv is a suppressor of abnormal neuroanatomy | larval stage phenotype of Cdc50^sgRNA.U6, Spyo\Cas9^ppk.PS

(Sung et al., 2024)

NOT Suppressor of

Statement

Reference

ctg^wgd/galectin^wgv is a non-suppressor of abnormal neuroanatomy | P-stage phenotype of drpr^Δ5

(Sung et al., 2024)

ctg^wgd/galectin^wgv is a non-suppressor of abnormal neuroanatomy | P-stage phenotype of drpr^indel

(Sung et al., 2024)

Other

Statement

Reference

ctg^wgd, galectin^wgv has abnormal neuroanatomy | larval stage phenotype

(Sung et al., 2024)

ctg^wgd, galectin^wgv has abnormal neuroanatomy | P-stage phenotype

(Sung et al., 2024)

Phenotype Manifest In

Suppressed by

Statement

Reference

ctg^wgd, galectin^wgv has larval dorsal multidendritic neuron ddaC | P-stage phenotype, suppressible by galectin^+tGR

(Sung et al., 2024)

ctg^wgd, galectin^wgv has dendrite | P-stage phenotype, suppressible by galectin^+tGR

(Sung et al., 2024)

ctg^wgd, galectin^wgv has larval dorsal multidendritic neuron ddaC | larval stage phenotype, suppressible | partially by galectin^+tGR

(Sung et al., 2024)

ctg^wgd, galectin^wgv has dendrite | larval stage phenotype, suppressible | partially by galectin^+tGR

(Sung et al., 2024)

ctg^wgd, galectin^wgv has larval dorsal multidendritic neuron ddaC | P-stage phenotype, suppressible by galectin^UAS.mRFP1/Scer\GAL4^Hml.PU

(Sung et al., 2024)

ctg^wgd, galectin^wgv has dendrite | P-stage phenotype, suppressible by galectin^UAS.mRFP1/Scer\GAL4^Hml.PU

(Sung et al., 2024)

ctg^wgd, galectin^wgv has larval dorsal multidendritic neuron ddaC | larval stage phenotype, suppressible by galectin^UAS.mRFP1/Scer\GAL4^Hml.PU

(Sung et al., 2024)

ctg^wgd, galectin^wgv has dendrite | larval stage phenotype, suppressible by galectin^UAS.mRFP1/Scer\GAL4^Hml.PU

(Sung et al., 2024)

ctg^wgd, galectin^wgv has larval dorsal multidendritic neuron ddaC | P-stage phenotype, suppressible by ctg^+tGR

(Sung et al., 2024)

ctg^wgd, galectin^wgv has dendrite | P-stage phenotype, suppressible by ctg^+tGR

(Sung et al., 2024)

ctg^wgd, galectin^wgv has larval dorsal multidendritic neuron ddaC | larval stage phenotype, suppressible | partially by ctg^+tGR

(Sung et al., 2024)

ctg^wgd, galectin^wgv has larval dorsal multidendritic neuron ddaC | larval stage phenotype, suppressible by ctg^UAS.mRFP1/Scer\GAL4^Hml.PU

(Sung et al., 2024)

ctg^wgd, galectin^wgv has dendrite | larval stage phenotype, suppressible | partially by ctg^+tGR

(Sung et al., 2024)

ctg^wgd, galectin^wgv has dendrite | P-stage phenotype, suppressible by ctg^UAS.mRFP1/Scer\GAL4^Hml.PU

(Sung et al., 2024)

ctg^wgd, galectin^wgv has larval dorsal multidendritic neuron ddaC | P-stage phenotype, suppressible by ctg^UAS.mRFP1/Scer\GAL4^Hml.PU

(Sung et al., 2024)

ctg^wgd, galectin^wgv has dendrite | larval stage phenotype, suppressible by ctg^UAS.mRFP1/Scer\GAL4^Hml.PU

(Sung et al., 2024)

NOT suppressed by

Statement

Reference

ctg^wgd, galectin^wgv has dendrite | P-stage phenotype, non-suppressible by galectin^UAS.mRFP1/Scer\GAL4^ppk.PG

(Sung et al., 2024)

ctg^wgd, galectin^wgv has dendrite | P-stage phenotype, non-suppressible by galectin^UAS.mRFP1/Scer\GAL4^A58

(Sung et al., 2024)

ctg^wgd, galectin^wgv has larval dorsal multidendritic neuron ddaC | P-stage phenotype, non-suppressible by ctg^UAS.mRFP1/Scer\GAL4^ppk.PG

(Sung et al., 2024)

ctg^wgd, galectin^wgv has larval dorsal multidendritic neuron ddaC | P-stage phenotype, non-suppressible by ctg^UAS.mRFP1/Scer\GAL4^A58

(Sung et al., 2024)

ctg^wgd, galectin^wgv has dendrite | P-stage phenotype, non-suppressible by ctg^UAS.mRFP1/Scer\GAL4^ppk.PG

(Sung et al., 2024)

ctg^wgd, galectin^wgv has dendrite | P-stage phenotype, non-suppressible by ctg^UAS.mRFP1/Scer\GAL4^A58

(Sung et al., 2024)

ctg^wgd, galectin^wgv has larval dorsal multidendritic neuron ddaC | P-stage phenotype, non-suppressible by galectin^UAS.mRFP1/Scer\GAL4^A58

(Sung et al., 2024)

ctg^wgd, galectin^wgv has larval dorsal multidendritic neuron ddaC | P-stage phenotype, non-suppressible by galectin^UAS.mRFP1/Scer\GAL4^ppk.PG

(Sung et al., 2024)

NOT Enhancer of

Statement

Reference

ctg^wgd/galectin^wgv is a non-enhancer of dendrite | P-stage phenotype of drpr^Δ5

(Sung et al., 2024)

ctg^wgd/galectin^wgv is a non-enhancer of larval dorsal multidendritic neuron ddaC | P-stage phenotype of drpr^Δ5

(Sung et al., 2024)

ctg^wgd/galectin^wgv is a non-enhancer of larval dorsal multidendritic neuron ddaC | P-stage phenotype of drpr^indel

(Sung et al., 2024)

ctg^wgd/galectin^wgv is a non-enhancer of dendrite | P-stage phenotype of drpr^indel

(Sung et al., 2024)

Suppressor of

Statement

Reference

ctg^wgd/galectin^wgv is a suppressor of larval dorsal multidendritic neuron ddaC | larval stage phenotype of Cdc50^sgRNA.U6, Spyo\Cas9^ppk.PS

(Sung et al., 2024)

ctg^wgd/galectin^wgv is a suppressor of dendrite | larval stage phenotype of Cdc50^sgRNA.U6, Spyo\Cas9^ppk.PS

(Sung et al., 2024)

NOT Suppressor of

Statement

Reference

ctg^wgd/galectin^wgv is a non-suppressor of dendrite | P-stage phenotype of drpr^Δ5

(Sung et al., 2024)

ctg^wgd/galectin^wgv is a non-suppressor of larval dorsal multidendritic neuron ddaC | P-stage phenotype of drpr^Δ5

(Sung et al., 2024)

ctg^wgd/galectin^wgv is a non-suppressor of larval dorsal multidendritic neuron ddaC | P-stage phenotype of drpr^indel

(Sung et al., 2024)

ctg^wgd/galectin^wgv is a non-suppressor of dendrite | P-stage phenotype of drpr^indel

(Sung et al., 2024)

Other

Statement

Reference

ctg^wgd, galectin^wgv has dendrite | larval stage phenotype

(Sung et al., 2024)

ctg^wgd, galectin^wgv has larval dorsal multidendritic neuron ddaC | larval stage phenotype

(Sung et al., 2024)

ctg^wgd, galectin^wgv has dendrite | P-stage phenotype

(Sung et al., 2024)

ctg^wgd, galectin^wgv has larval dorsal multidendritic neuron ddaC | P-stage phenotype

(Sung et al., 2024)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

galectin^wgv

hdg^wgv

(Sung et al., 2024)

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

Open Close