FlyBase Allele Report: Scer\GAL4[Hml.PU]

General Information

Symbol

Scer\GAL4^Hml.PU

Species

S. cerevisiae

Name

Hemolectin promoter construct of Unknown

FlyBase ID

FBal0314790

Feature type

allele

Associated gene

Scer\GAL4

Associated Insertion(s)

Carried in Construct

P{Hml-GAL4.U}

Also Known As

Hml-Gal4

Transgenic product class

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

Mutagen

in vitro construct

(FlyBase Curators, 2025-)

Progenitor genotype

Carried in construct

P{Hml-GAL4.U}

Cytology

Description

Hml regulatory sequences control expression of a GAL4 driver.

(FlyBase Curators, 2025-)

FlyBase curator comment: this entry represents a transgenic construct where the particular construct used cannot be determined.

(FlyBase Curators, 2025-)

Allele components

Component

Use(s)

Regulatory region(s)

Hml

Encoded product / tool

GAL4

binary expression system - driver

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal immune response | adult stage, with Arf1^GD12522

(Khadilkar et al., 2017)

abnormal immune response | adult stage, with asrij^GD2167

(Khadilkar et al., 2017)

abnormal immune response | adult stage, with Hmgcl^HMC03435

(Krejčová et al., 2025)

abnormal immune response | adult stage, with Hmgs^HMC04928

(Krejčová et al., 2025)

increased mortality | conditional, with Hmgcl^HMC03435

(Krejčová et al., 2025)

increased mortality | conditional, with Hmgs^HMC04928

(Krejčová et al., 2025)

viable, with Hsap\APOL1^{G0.UAS.Tag:FLAG}

(Fu et al., 2017)

viable, with Hsap\APOL1^{G1.UAS.Tag:FLAG}

(Fu et al., 2017)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

galectin^UAS.mRFP1/Scer\GAL4^Hml.PU is a suppressor of abnormal neuroanatomy | P-stage phenotype of ctg^wgd, galectin^wgv

(Sung et al., 2024)

galectin^UAS.mRFP1/Scer\GAL4^Hml.PU is a suppressor of abnormal neuroanatomy | larval stage phenotype of ctg^wgd, galectin^wgv

(Sung et al., 2024)

ctg^UAS.mRFP1/Scer\GAL4^Hml.PU is a suppressor of abnormal neuroanatomy | P-stage phenotype of ctg^wgd, galectin^wgv

(Sung et al., 2024)

ctg^UAS.mRFP1/Scer\GAL4^Hml.PU is a suppressor of abnormal neuroanatomy | larval stage phenotype of ctg^wgd, galectin^wgv

(Sung et al., 2024)

Phenotype Manifest In

Enhanced by

Statement

Reference

Dora^{WT.UAS.Tag:HA}, Scer\GAL4^Hml.PU has hemocyte phenotype, enhanceable by SCAR^GD11380, Scer\GAL4^Hml.PU

(Molina-Pelayo et al., 2022)

Dora^{WT.UAS.Tag:HA}, Scer\GAL4^Hml.PU has filopodium | increased number phenotype, enhanceable by SCAR^GD11380, Scer\GAL4^Hml.PU

(Molina-Pelayo et al., 2022)

Suppressed by

Statement

Reference

Dora^{WT.UAS.Tag:HA}, Scer\GAL4^Hml.PU has hemocyte phenotype, suppressible by Act5C^KK109161, Scer\GAL4^Hml.PU

(Molina-Pelayo et al., 2022)

Dora^{WT.UAS.Tag:HA}, Scer\GAL4^Hml.PU has hemocyte phenotype, suppressible by chic^KK112358, Scer\GAL4^Hml.PU

(Molina-Pelayo et al., 2022)

Dora^{WT.UAS.Tag:HA}, Scer\GAL4^Hml.PU has filopodium | increased number phenotype, suppressible by Act5C^KK109161, Scer\GAL4^Hml.PU

(Molina-Pelayo et al., 2022)

Dora^{WT.UAS.Tag:HA}, Scer\GAL4^Hml.PU has filopodium | increased number phenotype, suppressible by chic^KK112358, Scer\GAL4^Hml.PU

(Molina-Pelayo et al., 2022)

Cdc42^V12.UAS, Scer\GAL4^Hml.PU has hemocyte phenotype, suppressible by Dora^GD6527, Scer\GAL4^Hml.PU

(Molina-Pelayo et al., 2022)

Cdc42^V12.UAS, Scer\GAL4^Hml.PU has filopodium | increased number phenotype, suppressible by Dora^GD6527, Scer\GAL4^Hml.PU

(Molina-Pelayo et al., 2022)

Dora^{WT.UAS.Tag:HA}, Scer\GAL4^Hml.PU has hemocyte phenotype, suppressible by dia^NIG.1768R/dia^GL00408, Scer\GAL4^Hml.PU

(Molina-Pelayo et al., 2022)

Dora^{WT.UAS.Tag:HA}, Scer\GAL4^Hml.PU has filopodium | increased number phenotype, suppressible by dia^NIG.1768R/dia^GL00408, Scer\GAL4^Hml.PU

(Molina-Pelayo et al., 2022)

Enhancer of

Statement

Reference

SCAR^GD11380, Scer\GAL4^Hml.PU is an enhancer of hemocyte phenotype of Dora^{WT.UAS.Tag:HA}, Scer\GAL4^Hml.PU

(Molina-Pelayo et al., 2022)

SCAR^GD11380, Scer\GAL4^Hml.PU is an enhancer of filopodium | increased number phenotype of Dora^{WT.UAS.Tag:HA}, Scer\GAL4^Hml.PU

(Molina-Pelayo et al., 2022)

Suppressor of

Statement

Reference

galectin^UAS.mRFP1/Scer\GAL4^Hml.PU is a suppressor of larval dorsal multidendritic neuron ddaC | P-stage phenotype of ctg^wgd, galectin^wgv

(Sung et al., 2024)

galectin^UAS.mRFP1/Scer\GAL4^Hml.PU is a suppressor of dendrite | P-stage phenotype of ctg^wgd, galectin^wgv

(Sung et al., 2024)

galectin^UAS.mRFP1/Scer\GAL4^Hml.PU is a suppressor of larval dorsal multidendritic neuron ddaC | larval stage phenotype of ctg^wgd, galectin^wgv

(Sung et al., 2024)

galectin^UAS.mRFP1/Scer\GAL4^Hml.PU is a suppressor of dendrite | larval stage phenotype of ctg^wgd, galectin^wgv

(Sung et al., 2024)

ctg^UAS.mRFP1/Scer\GAL4^Hml.PU is a suppressor of larval dorsal multidendritic neuron ddaC | larval stage phenotype of ctg^wgd, galectin^wgv

(Sung et al., 2024)

ctg^UAS.mRFP1/Scer\GAL4^Hml.PU is a suppressor of dendrite | P-stage phenotype of ctg^wgd, galectin^wgv

(Sung et al., 2024)

ctg^UAS.mRFP1/Scer\GAL4^Hml.PU is a suppressor of larval dorsal multidendritic neuron ddaC | P-stage phenotype of ctg^wgd, galectin^wgv

(Sung et al., 2024)

ctg^UAS.mRFP1/Scer\GAL4^Hml.PU is a suppressor of dendrite | larval stage phenotype of ctg^wgd, galectin^wgv

(Sung et al., 2024)

dia^NIG.1768R/dia^GL00408, Scer\GAL4^Hml.PU is a suppressor of filopodium | increased number phenotype of Dora^{WT.UAS.Tag:HA}, Scer\GAL4^Hml.PU

(Molina-Pelayo et al., 2022)

Act5C^KK109161, Scer\GAL4^Hml.PU is a suppressor of hemocyte phenotype of Dora^{WT.UAS.Tag:HA}, Scer\GAL4^Hml.PU

(Molina-Pelayo et al., 2022)

chic^KK112358, Scer\GAL4^Hml.PU is a suppressor of hemocyte phenotype of Dora^{WT.UAS.Tag:HA}, Scer\GAL4^Hml.PU

(Molina-Pelayo et al., 2022)

Act5C^KK109161, Scer\GAL4^Hml.PU is a suppressor of filopodium | increased number phenotype of Dora^{WT.UAS.Tag:HA}, Scer\GAL4^Hml.PU

(Molina-Pelayo et al., 2022)

chic^KK112358, Scer\GAL4^Hml.PU is a suppressor of filopodium | increased number phenotype of Dora^{WT.UAS.Tag:HA}, Scer\GAL4^Hml.PU

(Molina-Pelayo et al., 2022)

Dora^GD6527, Scer\GAL4^Hml.PU is a suppressor of hemocyte phenotype of Cdc42^V12.UAS, Scer\GAL4^Hml.PU

(Molina-Pelayo et al., 2022)

Dora^GD6527, Scer\GAL4^Hml.PU is a suppressor of filopodium | increased number phenotype of Cdc42^V12.UAS, Scer\GAL4^Hml.PU

(Molina-Pelayo et al., 2022)

dia^NIG.1768R/dia^GL00408, Scer\GAL4^Hml.PU is a suppressor of hemocyte phenotype of Dora^{WT.UAS.Tag:HA}, Scer\GAL4^Hml.PU

(Molina-Pelayo et al., 2022)

rpr^UAS.cUa/Scer\GAL4^Hml.PU is a suppressor | partially of embryonic/larval lymph gland phenotype of C1GalTA^EY13370

(Fuwa et al., 2015)

rpr^UAS.cUa/Scer\GAL4^Hml.PU is a suppressor | partially of embryonic/larval plasmatocyte | ectopic phenotype of C1GalTA^EY13370

(Fuwa et al., 2015)

rpr^UAS.cUa/Scer\GAL4^Hml.PU is a suppressor | partially of lymph gland posterior signaling center cell phenotype of C1GalTA^EY13370

(Fuwa et al., 2015)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

Dora^GD6527/Scer\GAL4^Hml.PU rescues Dora^{WT.UAS.Tag:HA}

(Molina-Pelayo et al., 2022)

Partially rescues

PGRP-LB^UAS.PC.EGFP/Scer\GAL4^Hml.PU partially rescues PGRP-LB^Δ

(Charroux et al., 2018)

C1GalTA^UAS.cFa/Scer\GAL4^Hml.PU partially rescues C1GalTA^EY13370

(Fuwa et al., 2015)

Fails to rescue

PGRP-LB^UAS.PA.EGFP/Scer\GAL4^Hml.PU fails to rescue PGRP-LB^Δ

(Charroux et al., 2018)

PGRP-LB^UAS.PD.EGFP/Scer\GAL4^Hml.PU fails to rescue PGRP-LB^Δ

(Charroux et al., 2018)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

Hml^Gal4

(Charroux et al., 2018)

Scer\GAL4^Hml.PU

Name Synonyms

Hemolectin promoter construct of Unknown

Secondary FlyBase IDs

References (31)

Report Sections

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