FlyBase Allele Report: Dmel\Dgat2[KO]

General Information

Symbol

Dmel\Dgat2^KO

Species

D. melanogaster

Name

FlyBase ID

FBal0409620

Feature type

allele

Associated gene

Dmel\Dgat2

Associated Insertion(s)

TI{TI}Dgat2^KO

Carried in Construct

Key Links

Allele class

loss of function allele

Mutagen

Nature of the Allele

Allele class

loss of function allele

(Deng et al., 2025)

Mutagen

CRISPR/Cas9

(Deng et al., 2025)

gene targeting by homologous recombination

(Deng et al., 2025)

Progenitor genotype

Associated Insertion(s)

TI{TI}Dgat2^KO

Cytology

Description

An SV40-Disc\RFP^{DsRed.3xP3.cUa} marker is inserted into the first exon of Dgat2.

(Deng et al., 2025)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal thermotaxis | larval stage

(Deng et al., 2025)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

Dgat2^KO has abnormal thermotaxis | larval stage phenotype, suppressible | partially by Scer\GAL4^GMR11F02/Hsap\MOGAT2^UAS.Tag:HA

(Deng et al., 2025)

Dgat2^KO has abnormal thermotaxis | larval stage phenotype, suppressible | partially by Hsap\MOGAT3^UAS.Tag:HA/Scer\GAL4^GMR11F02

(Deng et al., 2025)

Dgat2^KO has abnormal thermotaxis | larval stage phenotype, suppressible by Scer\GAL4^Ir25a.PA/Ir25a^UAS.cLa

(Deng et al., 2025)

Dgat2^KO has abnormal thermotaxis | larval stage phenotype, suppressible by Ir25a^UAS.cLa/Scer\GAL4^GMR11F02

(Deng et al., 2025)

Dgat2^KO has abnormal thermotaxis | larval stage phenotype, suppressible by Ir21a^+tNa

(Deng et al., 2025)

Dgat2^KO has abnormal thermotaxis | larval stage phenotype, suppressible by br^Z4.UAS/Scer\GAL4^GMR11F02

(Deng et al., 2025)

NOT suppressed by

Statement

Reference

Dgat2^KO has abnormal thermotaxis | larval stage phenotype, non-suppressible by Hsap\DGAT2^UAS.Tag:HA/Scer\GAL4^GMR11F02

(Deng et al., 2025)

Dgat2^KO has abnormal thermotaxis | larval stage phenotype, non-suppressible by Scer\GAL4^GMR11F02/br^UAS.Z2.cDa

(Deng et al., 2025)

Dgat2^KO has abnormal thermotaxis | larval stage phenotype, non-suppressible by br^Z1.UAS/Scer\GAL4^GMR11F02

(Deng et al., 2025)

Dgat2^KO has abnormal thermotaxis | larval stage phenotype, non-suppressible by br^Z3.UAS/Scer\GAL4^GMR11F02

(Deng et al., 2025)

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescued by

Dgat2^KO is rescued by Dgat2^UAS.cDa/Scer\GAL4^Ir25a.PA

(Deng et al., 2025)

Dgat2^KO is rescued by Dgat2^UAS.cDa/Scer\GAL4^GMR11F02

(Deng et al., 2025)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Dgat2^KO

bishu-1^KO

(Deng et al., 2025)

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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