FlyBase Allele Report: Scer\GAL4[GMR11F02]

General Information

Symbol

Scer\GAL4^GMR11F02

Species

S. cerevisiae

Name

FlyBase ID

FBal0249674

Feature type

allele

Associated gene

Scer\GAL4

Associated Insertion(s)

Carried in Construct

P{GMR11F02-GAL4}

Also Known As

WP-Gal4, R11F02-Gal4, pdm2-GAL4, R11F02, 11F02-GAL4

Transgenic product class

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

Mutagen

in vitro construct

(Pfeiffer et al., 2011.2.9)

Progenitor genotype

Carried in construct

P{GMR11F02-GAL4}

Cytology

Description

A 3801 base pair fragment from the flanking non-coding or intronic region of pdm2 is fused upstream of a Drosophila core synthetic promoter (DSCP) that is followed by sequence encoding a GAL4 driver.

(Pfeiffer et al., 2011.2.9)

Allele components

Component

Use(s)

Regulatory region(s)

GMR11F02

Encoded product / tool

GAL4

binary expression system - driver

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

distribution deduced from reporter (Gal4 UAS)

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 15 -- larval stage

larval EL neuron

(Marshall and Heckscher, 2022)

larval stage

dorsal organ cool cell

(Knecht et al., 2016, Ni et al., 2016)

larval brain | restricted

(Ni et al., 2016)

larval ventral nerve cord | restricted

(Ni et al., 2016)

terminal organ | restricted

(Ni et al., 2016)

sensory neuron | subset

(Ni et al., 2016)

third instar larval stage

wing pouch

(Obata et al., 2014)

haltere disc

(Obata et al., 2014)

P-stage

wing

(Obata et al., 2014)

haltere

(Obata et al., 2014)

leg | restricted

(Obata et al., 2014)

adult stage

vest | intense | restricted

(Jenett and Svirskas, 2012.9.24)

adult antennal lobe | intense | restricted

(Jenett and Svirskas, 2012.9.24)

neuron of aristal sensillum

(Li et al., 2022)

adult stage | male

testis

(Obata et al., 2014)

Additional Information

Statement

Reference

ScerGAL4^GMR11F02 drives expression in the late-born subset of EL neurons, as well as a few other uncharacterized neurons

(Marshall and Heckscher, 2022)

ScerGAL4^GMR11F02 drives expression in both hot- and cold-sensing sensing neurons in the adult arista.

(Li et al., 2022)

Drives expression in EL neurons at late embryonic through larval stages; in dorsal organ cool cells at larval stages; in the wing pouch at larval and P-stages; and in both hot and cold-sensing neurons in the arista in adults.

(FlyBase Curators, 2017)

ScerGAL4^GMR11F02 drives expression in the dorsal organ cool cells, the terminal organ, ~100 cells in the brain and ventral nerve cord and sensory neurons in the tail.

(Ni et al., 2016)

ScerGAL4^GMR11F02 drives third instar larval expression the wing pouch region of the wing disc and in the haltere disc. At pupal stages ScerGAL4^GMR11F02 drives expression in the wings and halteres, and in a part of the legs. Adult expression is restricted to the testis.

(Obata et al., 2014)

Marker for

Reflects expression of

pdm2

(Marshall and Heckscher, 2022)

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal behavior | larval stage, with Fa2h^HMJ21019

(Li et al., 2024)

abnormal behavior | larval stage, with Fa2h^UAS.cLa

(Li et al., 2024)

abnormal behavior | larval stage, with Sod1^UAS.cAa

(Li et al., 2024)

abnormal developmental rate, with rpr^UAS.C

(Nemoto et al., 2023)

abnormal developmental rate, with trus^GD11610

(Takada et al., 2025)

abnormal immune response, with Dark^RNAi.UAS.cOa

(Obata et al., 2014)

abnormal size | adult stage, with InR^K1409A.UAS

(Shinoda et al., 2019)

abnormal thermotaxis | larval stage, with br^KK111704

(Deng et al., 2025)

abnormal thermotaxis | larval stage, with Dgat2^GD1854

(Deng et al., 2025)

decreased cell number | adult stage, with InR^K1409A.UAS

(Shinoda et al., 2019)

decreased cell size | adult stage, with InR^K1409A.UAS

(Shinoda et al., 2019)

decreased occurrence of cell division | third instar larval stage, with Sams^KK107709

(Obata et al., 2018)

decreased size | adult stage | female, with tra^JF03132

(Hérault et al., 2024)

increased size | adult stage | male, with tra^UAS.cFa

(Hérault et al., 2024)

melanotic necrosis, with Dark^RNAi.UAS.cOa

(Obata et al., 2014)

melanotic necrosis, with Dronc^RNAi.UAS.cOa

(Obata et al., 2014)

partially lethal - majority die, with trus^GD11610

(Takada et al., 2025)

some die during P-stage, with trus^GD11610

(Takada et al., 2025)

visible | adult stage, with Sams^KK107709

(Obata et al., 2018)

visible | adult stage, with trus^GD11610

(Takada et al., 2025)

visible | adult stage | female, with tra^JF03132

(Hérault et al., 2024)

visible | adult stage | male, with tra^UAS.cFa

(Hérault et al., 2024)

Phenotype Manifest In

haltere, with trus^GD11610

(Takada et al., 2025)

macrochaeta | increased number, with trus^GD11610

(Takada et al., 2025)

wing, with Dark^RNAi.UAS.cOa

(Obata et al., 2014)

wing, with Dronc^RNAi.UAS.cOa

(Obata et al., 2014)

wing, with InR^K1409A.UAS

(Shinoda et al., 2019)

wing, with Sams^KK107709

(Obata et al., 2018)

wing | female, with tra^JF03132

(Hérault et al., 2024)

wing | male, with tra^UAS.cFa

(Hérault et al., 2024)

wing blade | absent, with trus^GD11610

(Takada et al., 2025)

wing disc | third instar larval stage, with Sams^KK107709

(Obata et al., 2018)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

InR^K1409A.UAS, Scer\GAL4^GMR11F02 has abnormal size | adult stage phenotype, suppressible | partially by Diap1[+]/Diap1⁴

(Shinoda et al., 2019)

InR^K1409A.UAS, Scer\GAL4^GMR11F02 has decreased cell size | adult stage phenotype, suppressible | partially by Diap1[+]/Diap1⁴

(Shinoda et al., 2019)

InR^K1409A.UAS, Scer\GAL4^GMR11F02 has decreased cell number | adult stage phenotype, suppressible | partially by Diap1[+]/Diap1⁴

(Shinoda et al., 2019)

NOT Enhancer of

Statement

Reference

Scer\GAL4^GMR11F02/Hsap\KCNJ2^UAS.cUa is a non-enhancer of abnormal behavior | adult stage phenotype of Hsap\KCNJ2^UAS.cUa, Scer\GAL4^Or42b.PF

(Li et al., 2022)

Suppressor of

Statement

Reference

Scer\GAL4^GMR11F02/Hsap\MOGAT2^UAS.Tag:HA is a suppressor | partially of abnormal thermotaxis | larval stage phenotype of Dgat2^KO

(Deng et al., 2025)

Hsap\MOGAT3^UAS.Tag:HA/Scer\GAL4^GMR11F02 is a suppressor | partially of abnormal thermotaxis | larval stage phenotype of Dgat2^KO

(Deng et al., 2025)

Ir25a^UAS.cLa/Scer\GAL4^GMR11F02 is a suppressor of abnormal thermotaxis | larval stage phenotype of Dgat2^KO

(Deng et al., 2025)

br^Z4.UAS/Scer\GAL4^GMR11F02 is a suppressor of abnormal thermotaxis | larval stage phenotype of Dgat2^KO

(Deng et al., 2025)

InR^K1409A.UAS/Scer\GAL4^GMR11F02 is a suppressor of abnormal size | adult stage phenotype of Diap1⁴

(Shinoda et al., 2019)

InR^K1409A.UAS/Scer\GAL4^GMR11F02 is a suppressor of increased cell number | dominant | adult stage phenotype of Diap1⁴

(Shinoda et al., 2019)

NOT Suppressor of

Statement

Reference

Hsap\DGAT2^UAS.Tag:HA/Scer\GAL4^GMR11F02 is a non-suppressor of abnormal thermotaxis | larval stage phenotype of Dgat2^KO

(Deng et al., 2025)

Scer\GAL4^GMR11F02/br^UAS.Z2.cDa is a non-suppressor of abnormal thermotaxis | larval stage phenotype of Dgat2^KO

(Deng et al., 2025)

br^Z1.UAS/Scer\GAL4^GMR11F02 is a non-suppressor of abnormal thermotaxis | larval stage phenotype of Dgat2^KO

(Deng et al., 2025)

br^Z3.UAS/Scer\GAL4^GMR11F02 is a non-suppressor of abnormal thermotaxis | larval stage phenotype of Dgat2^KO

(Deng et al., 2025)

Scer\GAL4^GMR11F02/Hsap\KCNJ2^UAS.cUa is a non-suppressor of abnormal behavior | adult stage phenotype of Hsap\KCNJ2^UAS.cUa, Scer\GAL4^Or42b.PF

(Li et al., 2022)

Phenotype Manifest In

Suppressed by

Statement

Reference

InR^K1409A.UAS, Scer\GAL4^GMR11F02 has wing phenotype, suppressible | partially by Diap1[+]/Diap1⁴

(Shinoda et al., 2019)

Suppressor of

Statement

Reference

InR^K1409A.UAS/Scer\GAL4^GMR11F02 is a suppressor of wing phenotype of Diap1⁴

(Shinoda et al., 2019)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

Dgat2^UAS.cDa/Scer\GAL4^GMR11F02 rescues Dgat2^KO

(Deng et al., 2025)

Fa2h^CM.UAS/Scer\GAL4^GMR11F02 rescues Fa2h^KO1

(Li et al., 2024)

Fa2h^UAS.cLa/Scer\GAL4^GMR11F02 rescues Fa2h^KO1

(Li et al., 2024)

Fails to rescue

trus^UAS.cTa/Scer\GAL4^GMR11F02 fails to rescue trus^4-15/Df(3R)BSC847

(Takada et al., 2025)

Scer\GAL4^GMR11F02/Fa2h^NM.UAS fails to rescue Fa2h^KO1

(Li et al., 2024)

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

49828

w¹¹¹⁸; P{GMR11F02-GAL4}attP2

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Scer\GAL4^GMR11F02

Name Synonyms

Secondary FlyBase IDs

References (38)

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