FlyBase Allele Report: Dmel\trus[4-15]

General Information

Symbol

Dmel\trus^4-15

Species

D. melanogaster

Name

FlyBase ID

FBal0410056

Feature type

allele

Associated gene

Dmel\trus

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

CRISPR/Cas9

Nature of the Allele

Allele class

Mutagen

CRISPR/Cas9

(Takada et al., 2025)

Progenitor genotype

Cytology

Description

Single nucleotide deletion (coordinate 3R:12456811 , release 6 genome), resulting in a frameshift and premature stop codon.

(Takada et al., 2025)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal developmental rate (with Df(3R)BSC847)

(Takada et al., 2025)

abnormal developmental rate (with trus^35-2)

(Takada et al., 2025)

abnormal larval locomotory behavior (with Df(3R)BSC847)

(Takada et al., 2025)

abnormal size | larval stage (with Df(3R)BSC847)

(Takada et al., 2025)

abnormal size | larval stage (with trus^35-2)

(Takada et al., 2025)

decreased occurrence of cell division | larval stage (with Df(3R)BSC847)

(Takada et al., 2025)

decreased occurrence of cell division | larval stage (with trus^35-2)

(Takada et al., 2025)

female sterile (with Df(3R)BSC847), with Scer\GAL4^ci.PC, Scer\GAL4^en-GAL4-33, trus^UAS.cTa

(Takada et al., 2025)

fertile (with Df(3R)BSC847), with Scer\GAL4^da.G32, trus^UAS.cTa

(Takada et al., 2025)

lethal (with Df(3R)BSC847)

(Takada et al., 2025)

lethal (with trus^35-2)

(Takada et al., 2025)

majority die during embryonic stage (with Df(3R)BSC847)

(Takada et al., 2025)

some die during embryonic stage (with trus^35-2)

(Takada et al., 2025)

some die during pharate adult stage (with trus^35-2)

(Takada et al., 2025)

visible | adult stage (with Df(3R)BSC847), with Scer\GAL4^ci.PC, trus^UAS.cTa

(Takada et al., 2025)

Phenotype Manifest In

egg | absent (with Df(3R)BSC847), with Scer\GAL4^ci.PC, Scer\GAL4^en-GAL4-33, trus^UAS.cTa

(Takada et al., 2025)

egg chamber (with Df(3R)BSC847), with Scer\GAL4^ci.PC, Scer\GAL4^en-GAL4-33, trus^UAS.cTa

(Takada et al., 2025)

follicle cell (with Df(3R)BSC847), with Scer\GAL4^ci.PC, Scer\GAL4^en-GAL4-33, trus^UAS.cTa

(Takada et al., 2025)

haltere (with Df(3R)BSC847), with Scer\GAL4^ci.PC, trus^UAS.cTa

(Takada et al., 2025)

haltere disc (with Df(3R)BSC847)

(Takada et al., 2025)

larval brain (with Df(3R)BSC847)

(Takada et al., 2025)

larval brain (with trus^35-2)

(Takada et al., 2025)

larval ventral nerve cord (with Df(3R)BSC847)

(Takada et al., 2025)

larval ventral nerve cord (with trus^35-2)

(Takada et al., 2025)

leg (with Df(3R)BSC847), with Scer\GAL4^ci.PC, trus^UAS.cTa

(Takada et al., 2025)

leg disc (with Df(3R)BSC847)

(Takada et al., 2025)

nucleus | oogenesis (with Df(3R)BSC847), with Scer\GAL4^ci.PC, Scer\GAL4^en-GAL4-33, trus^UAS.cTa

(Takada et al., 2025)

nurse cell (with Df(3R)BSC847), with Scer\GAL4^ci.PC, Scer\GAL4^en-GAL4-33, trus^UAS.cTa

(Takada et al., 2025)

wing (with Df(3R)BSC847), with Scer\GAL4^ci.PC, trus^UAS.cTa

(Takada et al., 2025)

wing disc | larval stage (with Df(3R)BSC847)

(Takada et al., 2025)

wing disc | larval stage (with trus^35-2)

(Takada et al., 2025)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

trus^4-15/Df(3R)BSC847 has abnormal developmental rate phenotype, suppressible by Scer\GAL4^da.G32/Ilp8^KK112161

(Takada et al., 2025)

trus^4-15/Df(3R)BSC847 has abnormal developmental rate phenotype, suppressible by Scer\GAL4^da.G32/Xrp1^KK104477

(Takada et al., 2025)

trus^4-15/Df(3R)BSC847 has majority die during embryonic stage phenotype, suppressible | partially by Scer\GAL4^da.G32/Xrp1^KK104477

(Takada et al., 2025)

trus^4-15/Df(3R)BSC847 has decreased occurrence of cell division | larval stage phenotype, suppressible by Scer\GAL4^da.G32/Xrp1^KK104477

(Takada et al., 2025)

trus^4-15/Df(3R)BSC847 has abnormal size | larval stage phenotype, suppressible | partially by Scer\GAL4^da.G32/Xrp1^KK104477

(Takada et al., 2025)

trus^4-15/Df(3R)BSC847 has decreased occurrence of cell division | larval stage phenotype, suppressible by Scer\GAL4^da.G32/Ilp8^KK112161

(Takada et al., 2025)

NOT suppressed by

Statement

Reference

trus^4-15/Df(3R)BSC847 has lethal phenotype, non-suppressible by Scer\GAL4^da.G32/Ilp8^KK112161

(Takada et al., 2025)

trus^4-15/Df(3R)BSC847 has lethal phenotype, non-suppressible by Scer\GAL4^da.G32/Xrp1^KK104477

(Takada et al., 2025)

trus^4-15/Df(3R)BSC847 has abnormal size | larval stage phenotype, non-suppressible by Scer\GAL4^da.G32/Ilp8^KK112161

(Takada et al., 2025)

trus^4-15/Df(3R)BSC847 has abnormal size | larval stage phenotype, non-suppressible by Scer\GAL4^da.G32/BacA\p35^UAS.cHa

(Takada et al., 2025)

trus^4-15/Df(3R)BSC847 has decreased occurrence of cell division | larval stage phenotype, non-suppressible by Scer\GAL4^da.G32/BacA\p35^UAS.cHa

(Takada et al., 2025)

trus^4-15/Df(3R)BSC847 has abnormal developmental rate phenotype, non-suppressible by Scer\GAL4^da.G32/BacA\p35^UAS.cHa

(Takada et al., 2025)

trus^4-15/Df(3R)BSC847 has lethal phenotype, non-suppressible by Scer\GAL4^da.G32/BacA\p35^UAS.cHa

(Takada et al., 2025)

Phenotype Manifest In

Suppressed by

Statement

Reference

trus^4-15/Df(3R)BSC847 has larval brain phenotype, suppressible by Scer\GAL4^da.G32/Xrp1^KK104477

(Takada et al., 2025)

trus^4-15/Df(3R)BSC847 has wing disc | larval stage phenotype, suppressible | partially by Scer\GAL4^da.G32/Xrp1^KK104477

(Takada et al., 2025)

trus^4-15/Df(3R)BSC847 has larval brain phenotype, suppressible by Scer\GAL4^da.G32/Ilp8^KK112161

(Takada et al., 2025)

NOT suppressed by

Statement

Reference

trus^4-15/Df(3R)BSC847 has wing disc | larval stage phenotype, non-suppressible by Scer\GAL4^da.G32/Ilp8^KK112161

(Takada et al., 2025)

trus^4-15/Df(3R)BSC847 has larval brain phenotype, non-suppressible by Scer\GAL4^da.G32/BacA\p35^UAS.cHa

(Takada et al., 2025)

trus^4-15/Df(3R)BSC847 has wing disc | larval stage phenotype, non-suppressible by Scer\GAL4^da.G32/BacA\p35^UAS.cHa

(Takada et al., 2025)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescued by

trus^4-15/Df(3R)BSC847 is rescued by Scer\GAL4^da.G32/trus^UAS.EGFP

(Takada et al., 2025)

trus^4-15/Df(3R)BSC847 is rescued by trus^UAS.cTa/Scer\GAL4^da.G32

(Takada et al., 2025)

trus^4-15/Df(3R)BSC847 is rescued by Scer\GAL4^ci.PC/trus^UAS.cTa/Scer\GAL4^en-GAL4-33

(Takada et al., 2025)

Partially rescued by

trus^4-15/Df(3R)BSC847 is partially rescued by Scer\GAL4^ci.PC/trus^UAS.cTa

(Takada et al., 2025)

trus^4-15/Df(3R)BSC847 is partially rescued by trus^UAS.cTa/Scer\GAL4^en-GAL4-33

(Takada et al., 2025)

trus^4-15/Df(3R)BSC847 is partially rescued by trus^UAS.cTa/Scer\GAL4^repo

(Takada et al., 2025)

trus^4-15/Df(3R)BSC847 is partially rescued by trus^UAS.cTa/Scer\GAL4^e22c

(Takada et al., 2025)

Not rescued by

trus^4-15/Df(3R)BSC847 is not rescued by trus^UAS.cTa/Scer\GAL4^nub.PK

(Takada et al., 2025)

trus^4-15/Df(3R)BSC847 is not rescued by trus^UAS.cTa/Scer\GAL4^GMR11F02

(Takada et al., 2025)

trus^4-15/Df(3R)BSC847 is not rescued by trus^UAS.cTa/Scer\GAL4^elav.PLu

(Takada et al., 2025)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

trus^4-15

(Takada et al., 2025)

Name Synonyms

Secondary FlyBase IDs

References (1)

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