FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Gene: Dmel\homer
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General Information
Symbol
Dmel\homer
Species
D. melanogaster
Name
homer
Annotation Symbol
CG11324
Feature Type
protein_coding_gene
FlyBase ID
FBgn0025777
Gene Model Status
Current
Stock Availability
14 publicly available
Gene Summary
homer (homer) encodes a protein that acts as an adaptor protein binding to group I metabotropic glutamate receptors and other intracellular signaling proteins. It contributes to regulation of sleep, locomotor activity and ethanol tolerance. [Date last reviewed: 2019-03-07] (FlyBase Gene Snapshot)
All Summaries
Also Known As

Dhomer

Key Links
Genomic Location
Cytogenetic map
27A1-27A1
Sequence location
Recombination map
2-22
RefSeq locus
NT_033779 REGION:6719394..6723359
Sequence
Get Decorated FASTA
Genomic Maps
Other Genome Views
The following external sites may use different assemblies or annotations than FlyBase.
NCBI
UCSC
Ensembl
PopFly
Function
Gene Ontology (GO) Annotations (14 terms)
Molecular Function (2 terms)
Terms Based on Experimental Evidence (1 term)
CV Term
Evidence
References
enables protein binding
inferred from physical interaction with FLYBASE:Prosap; FB:FBgn0040752
(Diagana et al., 2002)
Terms Based on Predictions or Assertions (1 term)
CV Term
Evidence
References
enables G protein-coupled glutamate receptor binding
inferred from electronic annotation with InterPro:IPR044100, InterPro:IPR045027
(InterPro Project Members, 2004-)
inferred from biological aspect of ancestor with PANTHER:PTN000857479
(GO Reference Genome Project, 2011-)
Biological Process (8 terms)
Terms Based on Experimental Evidence (5 terms)
CV Term
Evidence
References
involved_in adult behavior
inferred from mutant phenotype
(Diagana et al., 2002)
involved_in behavioral response to ethanol
inferred from mutant phenotype
(Urizar et al., 2007)
involved_in positive regulation of circadian sleep/wake cycle, sleep
inferred from mutant phenotype
(Naidoo et al., 2012)
involved_in regulation of locomotion
inferred from mutant phenotype
(Diagana et al., 2002)
involved_in response to ethanol
inferred from direct assay
(Urizar et al., 2007)
Terms Based on Predictions or Assertions (3 terms)
CV Term
Evidence
References
involved_in G protein-coupled glutamate receptor signaling pathway
inferred from electronic annotation with InterPro:IPR044100
(InterPro Project Members, 2004-)
inferred from biological aspect of ancestor with PANTHER:PTN000857479
(GO Reference Genome Project, 2011-)
involved_in regulation of store-operated calcium entry
inferred from biological aspect of ancestor with PANTHER:PTN000857479
(GO Reference Genome Project, 2011-)
involved_in regulation of synaptic transmission, glutamatergic
inferred from biological aspect of ancestor with PANTHER:PTN000857479
(GO Reference Genome Project, 2011-)
Cellular Component (4 terms)
Terms Based on Experimental Evidence (2 terms)
CV Term
Evidence
References
located_in dendrite
inferred from direct assay
(Rolls et al., 2007, Diagana et al., 2002)
located_in endoplasmic reticulum
inferred from direct assay
(Diagana et al., 2002)
Terms Based on Predictions or Assertions (3 terms)
CV Term
Evidence
References
is_active_in cytoplasm
inferred from biological aspect of ancestor with PANTHER:PTN000857479
(GO Reference Genome Project, 2011-)
is_active_in dendrite
inferred from biological aspect of ancestor with PANTHER:PTN000857489
(GO Reference Genome Project, 2011-)
is_active_in plasma membrane
inferred from biological aspect of ancestor with PANTHER:PTN000857479
(GO Reference Genome Project, 2011-)
Gene Group (FlyBase)
Protein Family (UniProt)
-
Protein Signatures (InterPro)
Summaries
Gene Snapshot
homer (homer) encodes a protein that acts as an adaptor protein binding to group I metabotropic glutamate receptors and other intracellular signaling proteins. It contributes to regulation of sleep, locomotor activity and ethanol tolerance. [Date last reviewed: 2019-03-07]
Summary (Interactive Fly)

scaffolding protein required for the function of neural networks controlling locomotor activity and behavioral plasticity

Gene Model and Products
Number of Transcripts
6
Number of Unique Polypeptides
5

Please see the JBrowse view of Dmel\homer for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)
Isoform displayed:
Pfam protein domains
InterPro name
classification
start
end
Protein Domains (via SMART)
Isoform displayed:
SMART protein domains
InterPro name
classification
start
end
Structure
Protein 3D structure   (Predicted by AlphaFold)   (AlphaFold entry Q0E8S7)

If you don't see a structure in the viewer, refresh your browser.
Model Confidence:
  • Very high (pLDDT > 90)
  • Confident (90 > pLDDT > 70)
  • Low (70 > pLDDT > 50)
  • Very low (pLDDT < 50)

AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Experimentally Determined Structures
Crossreferences
Comments on Gene Model

Gene model reviewed during 5.45

Stop-codon suppression (UGA) postulated; FBrf0216885.

Gene model reviewed during 5.44

Gene model reviewed during 5.46

Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Assoc. CDS (aa)
homer-RA
FBtr0079306
NM_058048
1921
394
homer-RB
FBtr0079307
NM_164706
2388
397
homer-RD
FBtr0329892
NM_001273221
2923
394
homer-RE
FBtr0329893
NM_001042876
1921
531
homer-RF
FBtr0332330
NM_001273223
1930
397
homer-RG
FBtr0333346
NM_001273222
2397
400
Additional Transcript Data and Comments
Reported size (kB)

1.9 (longest cDNA)

(Xiao et al., 1998)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
UniProt
RefSeq ID
GenBank
homer-PA
FBpp0078936
42.7
394
7.58
O96607
NP_477396
AAF52428
homer-PB
FBpp0078937
43.0
397
7.18
Q9VM94
NP_723207
AAF52429
homer-PD
FBpp0302926
42.7
394
7.58
O96607
NP_001260150
AGB92686
homer-PE
FBpp0302927
57.3
531
9.02
Q0E8S7
NP_001036341
ABI31295
homer-PF
FBpp0304608
43.0
397
7.58
M9PB54
NP_001260152
AGB92688
homer-PG
FBpp0305538
43.4
400
7.58
M9PEX1
NP_001260151
AGB92687
Polypeptides with Identical Sequences

The group(s) of polypeptides indicated below share identical sequence to each other.

394 aa isoforms: homer-PA, homer-PD
Additional Polypeptide Data and Comments
Reported size (kDa)

394 (aa)

(Xiao et al., 1998)
Comments
External Data
Crossreferences
InterPro - A database of protein families, domains and functional sites
Linkouts
Sequences Consistent with the Gene Model
Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\homer using the Feature Mapper tool.

External Data
Crossreferences
Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
Linkouts
Expression Data
Testis-specificity index

The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).

2.15

Transcript Expression
in situ
Stage
Tissue/Position (including subcellular localization)
Reference
embryonic stage 1 -- 3
organism

Comment: maternally deposited

(Fisher et al., 2012)
embryonic stage 4 -- 6
organism | ubiquitous
(Fisher et al., 2012)
embryonic stage 9 -- 10
antennal primordium

Comment: reported as procephalic ectoderm primordium

(Fisher et al., 2012)
central brain primordium

Comment: reported as procephalic ectoderm primordium

(Fisher et al., 2012)
visual primordium

Comment: reported as procephalic ectoderm primordium

(Fisher et al., 2012)
dorsal head epidermis primordium

Comment: reported as procephalic ectoderm primordium

(Fisher et al., 2012)
lateral head epidermis primordium

Comment: reported as procephalic ectoderm primordium

(Fisher et al., 2012)
ventral head epidermis primordium

Comment: reported as procephalic ectoderm primordium

(Fisher et al., 2012)
organism | ubiquitous
(Fisher et al., 2012)
ventral nerve cord primordium
(Fisher et al., 2012)
embryonic stage 11 -- 12
anterior midgut primordium
(Fisher et al., 2012)
central brain primordium
(Fisher et al., 2012)
embryonic central brain glial cell
(Fisher et al., 2012)
embryonic central brain neuron
(Fisher et al., 2012)
larval lateral VNC glial cell
(Fisher et al., 2012)
lateral cord neuron
(Fisher et al., 2012)
organism | ubiquitous
(Fisher et al., 2012)
posterior midgut primordium
(Fisher et al., 2012)
ventral nerve cord primordium
(Fisher et al., 2012)
embryonic stage 12 -- 17
presumptive embryonic/larval central nervous system
(Diagana et al., 2002)
presumptive embryonic/larval peripheral nervous system
(Diagana et al., 2002)
chordotonal neuron
(Diagana et al., 2002)
bipolar dendrite neuron
(Diagana et al., 2002)
embryonic stage 13 -- 16
embryonic brain
(Fisher et al., 2012)
embryonic/larval midgut
(Fisher et al., 2012)
larval nervous system
(Fisher et al., 2012)
organism | ubiquitous
(Fisher et al., 2012)
larval ventral nerve cord
(Fisher et al., 2012)
embryonic stage 16 -- 17
larval central nervous system
(Diagana et al., 2002)
Additional Descriptive Data
Marker for
 
Subcellular Localization
CV Term
Polypeptide Expression
immunolocalization
Stage
Tissue/Position (including subcellular localization)
Reference
embryonic stage 12 -- 17
chordotonal neuron
(Diagana et al., 2002)
sensory neuron
(Diagana et al., 2002)
embryonic stage 16 -- 17
neuropil of larval ventral nerve cord
(Diagana et al., 2002)
neuron of larval ventral nerve cord
(Diagana et al., 2002)
larval stage
larval central nervous system
(Diagana et al., 2002)
pupal stage -- adult stage
adult central nervous system
(Diagana et al., 2002)
lamina
(Diagana et al., 2002)
medulla
(Diagana et al., 2002)
adult stage
adult brain | restricted
(Urizar et al., 2007)
ellipsoid body
(Urizar et al., 2007)
fan-shaped body
(Urizar et al., 2007)
adult central complex
(Urizar et al., 2007)
adult antennal lobe
(Urizar et al., 2007)
adult optic lobe | restricted
(Urizar et al., 2007)
protocerebral bridge
(Urizar et al., 2007)
mass spectroscopy
Stage
Tissue/Position (including subcellular localization)
Reference
adult stage
adult head
(Aradska et al., 2015)
western blot
Stage
Tissue/Position (including subcellular localization)
Reference
adult stage
adult head
(Diagana et al., 2002)
Additional Descriptive Data

homer expression in the dorsal neuropil of the embryonic ventral nerve cord overlaps that of synaptotagmin, suggesting synaptic localization.

(Diagana et al., 2002)
Marker for
 
Subcellular Localization
CV Term
Evidence
References
located_in dendrite
inferred from direct assay
(Rolls et al., 2007, Diagana et al., 2002)
located_in endoplasmic reticulum
inferred from direct assay
(Diagana et al., 2002)
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools

JBrowse - Visual display of RNA-Seq signals

View Dmel\homer in JBrowse
RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region
Bulk Downloads
RNA-Seq RPKM values for all genes
Reference
See Gelbart and Emmert, 2013 for analysis details and data files for all genes.
Developmental Proteome: Life Cycle
Developmental Proteome: Embryogenesis
External Data and Images
Linkouts
BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species
EMBL-EBI Single Cell Expression Atlas - Single cell expression across species
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data
Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
Flygut - An atlas of the Drosophila adult midgut
Images
FlyExpress - Embryonic expression images (BDGP data)
  • Stages(s) 4-6
  • Stages(s) 9-10
  • Stages(s) 11-12
  • Stages(s) 13-16
FlyBase Wiki
Image Based Resources
Alleles, Insertions, Transgenic Constructs, and Aberrations
Classical and Insertion Alleles ( 13 )
For All Classical and Insertion Alleles Show
 
Other relevant insertions
Transgenic Constructs ( 11 )
For All Alleles Carried on Transgenic Constructs Show
Transgenic constructs containing/affecting coding region of homer
Transgenic constructs containing regulatory region of homer
Aberrations (Deficiencies and Duplications) ( 2 )
Inferred from experimentation ( 2 )
Gene disrupted in
Df(2L)ED7007
(Naidoo et al., 2012)
Df(2L)Exel7027
(Ryder, 2004.4.26)
Inferred from location ( 7 )
Variants
Variant Molecular Consequences
Alleles Representing Disease-Implicated Variants
Phenotypes
Orthologs
Downloads
Download All DIOPT Orthologs
Human Orthologs (via DIOPT v9.1)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
Domainoid
eggNOG
Hieranoid
Homologene
Inparanoid
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
SonicParanoid
Alignment
Complementation?
Transgene?
Homo sapiens (Human) (10)
Hsap\HOMER2
12 of 14
Yes
Yes
2  
Hsap\HOMER1
10 of 14
No
Yes
1  
Hsap\HOMER3
8 of 14
No
Yes
Hsap\ENAH
1 of 14
No
No
Hsap\EVL
1 of 14
No
No
Hsap\LAMB1
1 of 14
No
No
9  
Hsap\SPRED1
1 of 14
No
No
1  
Hsap\SPRED2
1 of 14
No
No
Hsap\SPRED3
1 of 14
No
No
Hsap\VASP
1 of 14
No
No
1  
Model Organism Orthologs (via DIOPT v9.1)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
Domainoid
eggNOG
Hieranoid
Homologene
Inparanoid
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
SonicParanoid
Alignment
Complementation?
Transgene?
Rattus norvegicus (Norway rat) (13)
Rnor\Homer2
11 of 14
Yes
Yes
Rnor\Homer1
10 of 14
No
Yes
Rnor\Homer3
8 of 14
No
Yes
Rnor\Ccdc88a
1 of 14
No
No
Rnor\Enah
1 of 14
No
No
Rnor\Evl
1 of 14
No
No
Rnor\Kif20b
1 of 14
No
No
Rnor\Lama1
1 of 14
No
No
Rnor\Lamb2
1 of 14
No
No
Rnor\Spred1
1 of 14
No
No
Rnor\Spred2
1 of 14
No
No
Rnor\Spred3
1 of 14
No
No
Rnor\Vasp
1 of 14
No
No
Mus musculus (laboratory mouse) (11)
Mmus\Homer2
11 of 14
Yes
Yes
Mmus\Homer1
10 of 14
No
Yes
Mmus\Homer3
8 of 14
No
Yes
Mmus\Ccdc88a
1 of 14
No
No
Mmus\Enah
1 of 14
No
No
6  
Mmus\Evl
1 of 14
No
No
Mmus\Lamb2
1 of 14
No
No
Mmus\Spred1
1 of 14
No
No
Mmus\Spred2
1 of 14
No
No
Mmus\Spred3
1 of 14
No
No
Mmus\Vasp
1 of 14
No
No
Xenopus tropicalis (Western clawed frog) (7)
Xtro\homer1
9 of 13
Yes
Yes
Xtro\homer3
6 of 13
No
Yes
Xtro\homer2
2 of 13
No
Yes
Xtro\dmd.3
1 of 13
No
No
Xtro\spred1
1 of 13
No
No
Xtro\spred2
1 of 13
No
No
Xtro\spred3
1 of 13
No
No
Danio rerio (Zebrafish) (14)
Drer\homer1b
9 of 14
Yes
Yes
Drer\homer3b
8 of 14
No
Yes
Drer\LOC100330028
5 of 14
No
Yes
Drer\homer2
3 of 14
No
Yes
Drer\calcoco1b
1 of 14
No
Yes
Drer\enah
1 of 14
No
No
Drer\evla
1 of 14
No
No
Drer\evlb
1 of 14
No
No
Drer\spred1
1 of 14
No
No
Drer\spred2a
1 of 14
No
No
Drer\spred2b
1 of 14
No
No
Drer\spred3
1 of 14
No
No
Drer\vaspa
1 of 14
No
No
Drer\vaspb
1 of 14
No
No
Caenorhabditis elegans (Nematode, roundworm) (2)
Cele\epi-1
1 of 14
Yes
No
Cele\unc-34
1 of 14
Yes
No
Anopheles gambiae (African malaria mosquito) (3)
Agam\AgaP_AGAP010076
12 of 12
Yes
Yes
Agam\AgaP_AGAP010673
1 of 12
No
No
Agam\AgaP_AGAP012085
1 of 12
No
No
Arabidopsis thaliana (thale-cress) (0)
Saccharomyces cerevisiae (Brewer's yeast) (0)
Schizosaccharomyces pombe (Fission yeast) (1)
Spom\myo2
1 of 12
Yes
No
Escherichia coli (enterobacterium) (0)
Other Organism Orthologs (via OrthoDB)
Data provided directly from OrthoDB:homer. Refer to their site for version information.
Paralogs
Downloads
Download All DIOPT Paralogs
Paralogs (via DIOPT v9.1)
Gene Symbol
Score
Source
Compara
Domainoid
eggNOG
Homologene
Inparanoid
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
SonicParanoid
Alignment
Drosophila melanogaster (Fruit fly) (2)
ena
1 of 13
Spred
1 of 13
Human Disease Associations
FlyBase Human Disease Model Reports
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 1 )
Allele
Disease
Evidence
References
homerR102
model of  alcohol use disorder
CEA
(Urizar et al., 2007)
Potential Models Based on Orthology ( 1 )
Human Ortholog
Disease
Evidence
References
HOMER2; homer scaffold protein 2
model of  autosomal dominant nonsyndromic deafness 68
IEA
(FlyBase, 2019-)
Modifiers Based on Experimental Evidence ( 0 )
Allele
Disease
Interaction
References
Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)
Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
Homo sapiens (Human)
Gene name
Score
OMIM
OMIM Phenotype
DO term
Complementation?
Transgene?
HOMER2; homer scaffold protein 2
12 of 14
HOMER SCAFFOLD PROTEIN 2; HOMER2
 
HOMER1; homer scaffold protein 1
10 of 14
HOMER SCAFFOLD PROTEIN 1; HOMER1
       
      HOMER3; homer scaffold protein 3
      8 of 14
      604800
          Functional Complementation Data
          Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.
          Interactions
          Summary of Physical Interactions
          Summary of Genetic Interactions
          Interaction Browsers
          Starting gene(s)
          Interaction type
          Interacting gene(s)
          Reference
          Starting gene(s)
          Interaction type
          Interacting gene(s)
          Reference
          External Data
          Linkouts
          BioGRID - A database of protein and genetic interactions.
          DroID - A comprehensive database of gene and protein interactions.
          MIST (protein-protein) - An integrated Molecular Interaction Database
          Pathways
          Signaling Pathways (FlyBase)
          Metabolic Pathways
          FlyBase
          External Links
          External Data
          Linkouts
          KEGG Pathways - A collection of manually drawn pathway maps representing knowledge of molecular interaction, reaction and relation networks.
          Class of Gene
          Genomic Location and Detailed Mapping Data
          Chromosome (arm)
          2L
          Recombination map
          2-22
          Cytogenetic map
          27A1-27A1
          Sequence location
          FlyBase Computed Cytological Location
          Cytogenetic map
          Evidence for location
          27A1-27A1
          Limits computationally determined from genome sequence between P{EP}Sec61αEP2180 and P{lacW}Ate1k10809
          Experimentally Determined Cytological Location
          Cytogenetic map
          Notes
          References
          Experimentally Determined Recombination Data
          Location

          2-22

          (FlyBase, 2016)

          2-21.6

          (Comeron et al., 2012)
          Left of (cM)
          Right of (cM)
          Notes
          Stocks and Reagents
          Stocks (14)
          Genomic Clones (17)
           

          Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

          cDNA Clones (77)
           

          Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

          cDNA clones, fully sequenced
          BDGP DGC clones
          Other clones
          Drosophila Genomics Resource Center cDNA clones

          For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

          cDNA Clones, End Sequenced (ESTs)
          BDGP DGC clones
          Other clones
          RNAi and Array Information
          Linkouts
          DRSC - Results frm RNAi screens
          Antibody Information
          Laboratory Generated Antibodies
           

          polyclonal

          (Diagana et al., 2002)
          Commercially Available Antibodies
           
          Cell Line Information
          Publicly Available Cell Lines
           
            Other Stable Cell Lines
             
              Other Comments

              dsRNA made from templates generated with primers against this gene used in a genome-wide dsRNA interference (RNAi) screen to identify regulators of the signalling pathway leading from Ca2+-calcineurin to NFAT.

              (Gwack et al., 2006)

              dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology.

              (Kiger et al., 2003)

              homer operates in the ER and in dendrites to regulate the development and function of neural networks underlying locomotor control and behavioral plasticity.

              (Diagana et al., 2002)

              Mutants display defects in behavioural plasticity and the control of locomotor activity.

              (Diagana et al., 2002)

              Identification: Homer 1a sequence (from rat) was used to search GenBank databases, Drosophila sequence was identified.

              (Xiao et al., 1998)
              Relationship to Other Genes
              Source for database merge of

              Source for merge of: homer BEST:LD03829

              (Bayraktaroglu, 2000.11.2)
              Additional comments
              Nomenclature History
              Source for database identify of

              Source for identity of: homer CG11324

              (Wortman, 1999.11)
              Nomenclature comments
              Etymology
              Synonyms and Secondary IDs (13)
              Reported As
              Symbol Synonym
              BEST:LD03829
              CG11324
              (National Institute of Genetics Fly Stocks, 2022-, Kolkhof et al., 2017, Rosa-Ferreira et al., 2015, Hughes et al., 2014, Ni et al., 2010.12.1, Keleman et al., 2009.8.5, Roos et al., 2005)
              Dhom
              (Babu et al., 2002)
              Dhomer
              (Babu et al., 2002, Kaufmann et al., 2002)
              Dm Homer
              (Renfranz and Beckerle, 2002)
              Dvh
              Hom
              (Bottenberg et al., 2009)
              Homer
              (Scaplen and Petruccelli, 2021, Mariano et al., 2020, Wu et al., 2017, Schwartz et al., 2016, Dissel et al., 2015, Andlauer et al., 2014, Kaun et al., 2012, Morozova et al., 2012, Gwack et al., 2006)
              LD03829
              (Toba et al., 1999)
              dhom
              (Babu et al., 2002)
              homer
              (Bhandari et al., 2024, Peterson and Ahmad, 2024, Sutton et al., 2024, Li et al., 2022, Raun et al., 2021, Lathen et al., 2020, Awata et al., 2019, Gene Disruption Project members, 2018-, Rossi et al., 2017, Gupta et al., 2016, Androschuk et al., 2015, Grotewiel and Bettinger, 2015, Kavi et al., 2015, Hughes et al., 2014, Robinson and Atkinson, 2013, Izutsu et al., 2012, Japanese National Institute of Genetics, 2012.5.21, Miyashita et al., 2012, Murray et al., 2012, Naidoo et al., 2012, Awofala, 2011, Godena et al., 2011, Jungreis, 2011.11.18, Rolls, 2011, Perkins et al., 2009.8.10, Ruedi and Hughes, 2009, Yang et al., 2008, Buszczak et al., 2007, Hutchins and Rusconi, 2007, Rolls et al., 2007, Urizar et al., 2007, Zhang et al., 2006, Roos et al., 2005)
              Name Synonyms
              Drosophila Ves-1 homolog
              Homer
              (Shafer, 2025, Ly et al., 2018, Allada et al., 2017, Potdar and Sheeba, 2013, Bottenberg et al., 2009)
              d-Homer
              (Cai et al., 2001)
              homer
              (Segu and Kannan, 2023, Tomita et al., 2017, Rusconi et al., 2008, Yang et al., 2008)
              Secondary FlyBase IDs
              • FBgn0026588
              Datasets (0)
              Study focus (0)
              Experimental Role
              Project
              Project Type
              Title
              Study result (0)
              Result
              Result Type
              Title
              External Crossreferences and Linkouts ( 61 )
              Sequence Crossreferences
              NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.
              GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
              GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
              RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.
              UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.
              UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information
              Other crossreferences
              AlphaFold DB - AlphaFold provides open access to protein structure predictions for the human proteome and other key proteins of interest, to accelerate scientific research.
              BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
              DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species
              EMBL-EBI Single Cell Expression Atlas - Single cell expression across species
              FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data
              FlyMine - An integrated database for Drosophila genomics
              InterPro - A database of protein families, domains and functional sites
              KEGG Genes - Molecular building blocks of life in the genomic space.
              MARRVEL_MODEL - MARRVEL (model organism gene)
              Linkouts
              BioGRID - A database of protein and genetic interactions.
              Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones
              DroID - A comprehensive database of gene and protein interactions.
              DRSC - Results frm RNAi screens
              Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
              FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
              FlyCyc Genes - Genes from a BioCyc PGDB for Dmel
              Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
              Flygut - An atlas of the Drosophila adult midgut
              iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)
              Interactive Fly - A cyberspace guide to Drosophila development and metazoan evolution
              KEGG Pathways - A collection of manually drawn pathway maps representing knowledge of molecular interaction, reaction and relation networks.
              MIST (protein-protein) - An integrated Molecular Interaction Database
              References (111)