FB2021_06, released December 14, 2021

Gene: Dmel\EndoGI

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General Information
Symbol
Dmel\EndoGI
Species
D. melanogaster
Name
Endonuclease G inhibitor
Annotation Symbol
CG4930
Feature Type
protein_coding_gene
FlyBase ID
FBgn0028515
Gene Model Status
Current
Stock Availability
5 publicly available
Gene Summary
Endonuclease G inhibitor (EndoGI) encodes an inhibitor of the enzyme encoded by EndoG by tight binding to the enzymatic active site. Since the product of EndoG is mostly or entirely localized in mitochondria, the product of EndoGI has been suggested to protect cells against mis-localization of the enzyme. [Date last reviewed: 2019-03-07] (FlyBase Gene Snapshot)
All Summaries
Also Known As

BG:DS07473.2

Key Links
Genomic Location
Cytogenetic map
35F1-35F1
Sequence location
Recombination map
2-52
RefSeq locus
NT_033779 REGION:16257688..16259511
Sequence
Get Decorated FASTA
Genomic Maps
Other Genome Views
The following external sites may use different assemblies or annotations than FlyBase.
NCBI
UCSC
Ensembl
PopFly
Function
GO Summary Ribbons
Gene Ontology (GO) Annotations (4 terms)
Molecular Function (1 term)
Terms Based on Experimental Evidence (1 term)
CV Term
Evidence
References
enables ribonuclease inhibitor activity
inferred from direct assay
(Temme et al., 2009)
Terms Based on Predictions or Assertions (0 terms)
Biological Process (2 terms)
Terms Based on Experimental Evidence (2 terms)
CV Term
Evidence
References
involved_in negative regulation of endoribonuclease activity
inferred from direct assay
(Temme et al., 2009)
involved_in positive regulation of Notch signaling pathway
inferred from mutant phenotype
(O'Keefe et al., 2011)
Terms Based on Predictions or Assertions (0 terms)
Cellular Component (1 term)
Terms Based on Experimental Evidence (1 term)
CV Term
Evidence
References
located_in nucleus
inferred from direct assay
(O'Keefe et al., 2011, Temme et al., 2009)
Terms Based on Predictions or Assertions (0 terms)
Gene Group (FlyBase)
Pathway (FlyBase)
Protein Family (UniProt)
-
Protein Signatures (InterPro)
Summaries
Gene Snapshot
Endonuclease G inhibitor (EndoGI) encodes an inhibitor of the enzyme encoded by EndoG by tight binding to the enzymatic active site. Since the product of EndoG is mostly or entirely localized in mitochondria, the product of EndoGI has been suggested to protect cells against mis-localization of the enzyme. [Date last reviewed: 2019-03-07]
Pathway (FlyBase)
Positive Regulators of Notch Signaling Pathway -
The Notch receptor signaling pathway is activated by the binding of the transmembrane receptor Notch (N) to transmembrane ligands, Dl or Ser, presented on adjacent cells. This results in the proteolytic cleavage of N, releasing the intracellular domain (NICD). NICD translocates into the nucleus, interacting with Su(H) and mam to form a transcription complex, which up-regulates transcription of Notch-responsive genes. Positive regulators of the pathway enhance the signal from the sending cell or the response in the receiving cell. (Adapted from FBrf0225731 and FBrf0192604).
Gene Model and Products
Number of Transcripts
3
Number of Unique Polypeptides
1

Please see the JBrowse view of Dmel\EndoGI for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)
Isoform displayed:
Pfam protein domains
InterPro name
classification
start
end
Protein Domains (via SMART)
Isoform displayed:
SMART protein domains
InterPro name
classification
start
end
Comments on Gene Model

Gene model reviewed during 5.44

Gene model reviewed during 5.55

Sequence Ontology: Class of Gene
nuclear_gene
protein_coding_gene
Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Assoc. CDS (aa)
EndoGI-RA
FBtr0080824
NM_135937
1360
359
EndoGI-RB
FBtr0331442
NM_001273560
1406
359
EndoGI-RC
FBtr0331443
NM_001273561
1438
359
Additional Transcript Data and Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
RefSeq ID
GenBank
EndoGI-PA
FBpp0080382
40.6
359
4.20
NP_609781
AAF53507
EndoGI-PB
FBpp0303859
40.6
359
4.20
NP_001260489
AGB93024
EndoGI-PC
FBpp0303860
40.6
359
4.20
NP_001260490
AGB93025
Polypeptides with Identical Sequences

The group(s) of polypeptides indicated below share identical sequence to each other.

359 aa isoforms: EndoGI-PA, EndoGI-PB, EndoGI-PC
Additional Polypeptide Data and Comments
Reported size (kDa)
Comments
External Data
Crossreferences
InterPro - A database of protein families, domains and functional sites
Linkouts
Sequences Consistent with the Gene Model
Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\EndoGI using the Feature Mapper tool.

External Data
Crossreferences
Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
Linkouts
Expression Data
Expression Summary Ribbons
Colored tiles in ribbon indicate that expression data has been curated by FlyBase for that anatomical location. Colorless tiles indicate that there is no curated data for that location.
For complete stage-specific expression data, view the modENCODE Development RNA-Seq section under High-Throughput Expression below.
Transcript Expression
in situ
Stage
Tissue/Position (including subcellular localization)
Reference
wandering third instar larval stage
wing pouch | restricted
(Molnar et al., 2012)
wing hinge primordium | restricted
(Molnar et al., 2012)
Additional Descriptive Data
Marker for
 
Subcellular Localization
CV Term
Polypeptide Expression
immunolocalization
Stage
Tissue/Position (including subcellular localization)
Reference
embryonic stage
organism | ubiquitous
(O'Keefe et al., 2011)
embryonic stage 4
organism
(Temme et al., 2009)
larval stage
testis
(O'Keefe et al., 2011)
imaginal disc
(O'Keefe et al., 2011)
larval ventral nerve cord | restricted
(O'Keefe et al., 2011)
embryonic/larval brain | restricted
(O'Keefe et al., 2011)
embryonic/larval salivary gland
(O'Keefe et al., 2011)
oogenesis
follicle cell
(Temme et al., 2009)
nurse cell
(Temme et al., 2009)
mass spectroscopy
Stage
Tissue/Position (including subcellular localization)
Reference
adult stage
adult head
(Aradska et al., 2015)
western blot
Stage
Tissue/Position (including subcellular localization)
Reference
embryonic stage -- adult stage
organism
(Temme et al., 2009)
Additional Descriptive Data

EndoGI expression is widespread and predominantly nuclear. It is supplied maternally to the embryo and uniformly labels embryonic nuclei. In larvae, it is ubiquitously expressed in many tissues including imaginal discs and testis. By contrast, only a subset of cells within the larval brain and ventral nerve cord express EndoGI. It is dynamically expressed within the salivary glands, being present in the nucleus in early third instar larvae but absent from most nuclei in late third instar larvae. A small number of salivary gland cells show cytoplasmic localization of EndoGI in late third instar larvae.

(O'Keefe et al., 2011)

EndoGI protein is detected at all stages assayed. EndoGI protein is localized to the nuclei of follicle cells and nurse cells in ovaries.

(Temme et al., 2009)
Marker for
 
Subcellular Localization
CV Term
Evidence
References
located_in nucleus
inferred from direct assay
(O'Keefe et al., 2011, Temme et al., 2009)
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools

GBrowse - Visual display of RNA-Seq signals

View Dmel\EndoGI in GBrowse 2
RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region
Bulk Downloads
RNA-Seq RPKM values for all genes
Reference
See Gelbart and Emmert, 2013 for analysis details and data files for all genes.
Developmental Proteome: Life Cycle
Developmental Proteome: Embryogenesis
External Data and Images
Linkouts
DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species
EMBL-EBI Single Cell Expression Atlas - Single cell expression across species
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data
Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
Flygut - An atlas of the Drosophila adult midgut
Images
FlyBase Wiki
Image Based Resources
Alleles, Insertions, Transgenic Constructs, and Aberrations
Classical and Insertion Alleles ( 5 )
For All Classical and Insertion Alleles Show
 
Other relevant insertions
Transgenic Constructs ( 6 )
For All Alleles Carried on Transgenic Constructs Show
Transgenic constructs containing/affecting coding region of EndoGI
Transgenic constructs containing regulatory region of EndoGI
Aberrations (Deficiencies and Duplications) ( 2 )
Inferred from experimentation ( 2 )
Gene disrupted in
Df(2L)r10
(Temme et al., 2009)
Df(2L)RA5
(Temme et al., 2009)
Inferred from location ( 0 )
Alleles Representing Disease-Implicated Variants
Phenotypes
For more details about a specific phenotype click on the relevant allele symbol.
Lethality
Allele
lethal | recessive
partially lethal, with Dcr-2UAS.cDa, Scer\GAL4elav.PLu
partially lethal - majority die
viable, with Scer\GAL4Mef2.PR
Sterility
Allele
female fertile
male sterile
male sterile (with Df(2L)RA5)
Other Phenotypes
Allele
abnormal flight
abnormal neuroanatomy | embryonic stage
decreased body size (with Df(2L)RA5)
increased cell number | somatic clone, with Scer\GAL4Act5C.PP
some die during embryonic stage, with Dcr-2UAS.cDa, Scer\GAL4elav.PLu
some die during third instar larval stage
uncoordinated | adult stage (with Df(2L)RA5)
visible, with Scer\GAL4ap-md544
visible, with Scer\GAL4en-e16E
visible (with Df(2L)RA5)
visible | somatic clone, with Scer\GAL4Act5C.PP
Phenotype manifest in
Allele
eye | somatic clone, with Scer\GAL4Act5C.PP
larval intersegmental nerve
larval intersegmental nerve branch ISNb of A1-7
larval segmental nerve branch SNa of A1-7
larval segmental nerve branch SNc of A1-7
leg (with Df(2L)RA5)
wing (with Df(2L)RA5)
wing | posterior, with Scer\GAL4en-e16E
wing disc | somatic clone, with Scer\GAL4Act5C.PP
wing margin bristle, with Scer\GAL4ap-md544
wing vein, with Scer\GAL4en-e16E
Orthologs
Downloads
Download All DIOPT Orthologs
Download All OrthoDB Orthologs
Human Orthologs (via DIOPT v8.0)
Homo sapiens (Human) (2)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
eggNOG
Hieranoid
Homologene
Inparanoid
Isobase
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
RoundUp
TreeFam
ZFIN
Alignment
Complementation?
Transgene?
Hsap\XRCC5
2 of 15
Yes
No
Hsap\XRCC6
1 of 15
No
No
1  
Model Organism Orthologs (via DIOPT v8.0)
Mus musculus (laboratory mouse) (2)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
eggNOG
Hieranoid
Homologene
Inparanoid
Isobase
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
RoundUp
TreeFam
ZFIN
Alignment
Complementation?
Transgene?
Mmus\Xrcc5
2 of 15
Yes
No
Mmus\Xrcc6
1 of 15
No
No
Rattus norvegicus (Norway rat) (2)
Rnor\Xrcc5
2 of 13
Yes
No
Rnor\Xrcc6
1 of 13
No
No
Xenopus tropicalis (Western clawed frog) (2)
Xtro\xrcc5
1 of 12
Yes
No
Xtro\xrcc6
1 of 12
Yes
No
Danio rerio (Zebrafish) (3)
Drer\xrcc5
2 of 15
Yes
No
Drer\LOC110438490
1 of 15
No
No
Drer\xrcc6
1 of 15
No
No
Caenorhabditis elegans (Nematode, roundworm) (2)
Cele\cku-80
2 of 15
Yes
No
Cele\cku-70
1 of 15
No
No
Arabidopsis thaliana (thale-cress) (1)
Atha\KU70
1 of 9
Yes
No
Saccharomyces cerevisiae (Brewer's yeast) (2)
Scer\YKU80
2 of 15
Yes
No
Scer\YKU70
1 of 15
No
No
Schizosaccharomyces pombe (Fission yeast) (2)
Spom\pku70
1 of 12
Yes
No
Spom\pku80
1 of 12
Yes
No
Ortholog(s) in Drosophila Species (via OrthoDB v9.1) ( EOG09190DFN )
Organism
Common Name
Gene
AAA Syntenic Ortholog
Multiple Dmel Genes in this Orthologous Group
Drosophila suzukii
Spotted wing Drosophila
Dsuz\DS10_00000960
Drosophila simulans
Dsim\GD24044
Drosophila sechellia
Dsec\GM18658
Drosophila erecta
Dere\GG25195
Drosophila yakuba
Dyak\GE21376
Drosophila ananassae
Dana\GF14961
Drosophila pseudoobscura pseudoobscura
Dpse\GA18533
Drosophila persimilis
Dper\GL25983
Drosophila willistoni
Dwil\GK18285
Drosophila virilis
Dvir\GJ18019
Drosophila mojavensis
Dmoj\GI10268
Drosophila grimshawi
Dgri\GH13511
Orthologs in non-Drosophila Dipterans (via OrthoDB v9.1) ( EOG091508U4 )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Musca domestica
House fly
Mdoa\17023182
Musca domestica
House fly
Mdoa\17023183
Musca domestica
House fly
Mdoa\17023181
Glossina morsitans
Tsetse fly
Gmor\GMOY001434
Lucilia cuprina
Australian sheep blowfly
Lcup\FF38_03899
Orthologs in non-Dipteran Insects (via OrthoDB v9.1) ( EOG090W0N5D )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Danaus plexippus
Monarch butterfly
Dple\DPOGS204693-PA
Heliconius melpomene
Postman butterfly
Hmel\HMEL008253
Apis florea
Little honeybee
Aflo\3294660788
Apis mellifera
Western honey bee
Amel\LOC552750
Bombus impatiens
Common eastern bumble bee
Bimp\BIMP15240
Bombus terrestris
Buff-tailed bumblebee
Bter\15208674
Linepithema humile
Argentine ant
Lhum\LH18130
Megachile rotundata
Alfalfa leafcutting bee
Mrot\MROTU:002e1a
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG007880
Dendroctonus ponderosae
Mountain pine beetle
Dpod\YQE_12618
Pediculus humanus
Human body louse
Phum\PHUM529370
Rhodnius prolixus
Kissing bug
Rpro\RPRC012409
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI001555
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI070246
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI41812
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI086733
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI068626
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI081313
Zootermopsis nevadensis
Nevada dampwood termite
Znev\Znev_05675
Orthologs in non-Insect Arthropods (via OrthoDB v9.1) ( EOG090X0NED )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Ixodes scapularis
Black-legged tick
Isca\ISCW017702
Stegodyphus mimosarum
African social velvet spider
Smim\KFM64580.1
Tetranychus urticae
Two-spotted spider mite
Turt\tetur15g03380
Tetranychus urticae
Two-spotted spider mite
Turt\tetur08g05290
Orthologs in non-Arthropod Metazoa (via OrthoDB v9.1) ( EOG091G11VD )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Strongylocentrotus purpuratus
Purple sea urchin
Spur\Sp-Bmp5-8
Strongylocentrotus purpuratus
Purple sea urchin
Spur\Sp-Ku86l
Ciona intestinalis
Vase tunicate
Cint\zf(c2h2)-102
Gallus gallus
Domestic chicken
Ggal\XRCC5
Paralogs
Downloads
Download All DIOPT Paralogs
Paralogs (via DIOPT v8.0)
Drosophila melanogaster (Fruit fly) (2)
Gene Symbol
Score
Source
Compara
eggNOG
Homologene
Inparanoid
Isobase
OrthoDB
OrthoFinder
orthoMCL
Panther
RoundUp
Alignment
Ku80
3 of 10
Irbp
2 of 10
Human Disease Associations
FlyBase Human Disease Model Reports
    Disease Model Summary Ribbon
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Evidence
    References
    Potential Models Based on Orthology ( 0 )
    Human Ortholog
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Interaction
    References
    Disease Associations of Human Orthologs (via DIOPT v8.0 and OMIM)
    Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
    Homo sapiens (Human)
    Gene name
    Score
    OMIM
    OMIM Phenotype
    DO term
    Complementation?
    Transgene?
    Functional Complementation Data
    Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.
    Interactions
    Summary of Physical Interactions
    esyN Network Diagram
    Show neighbor-neighbor interactions:
    Select Layout:
    Legend:
    Protein
    RNA
    Selected Interactor(s)
    Interactions Browser
    View in Interactions Browser
    Please see the Physical Interaction reports below for full details
    protein-protein
    Physical Interaction
    Assay
    References
    EndoGI - 14-3-3ε
    cosedimentation, molecular weight
    (Temme et al., 2009)
    EndoGI - Akr1B
    experimental knowledge based
    (Guruharsha et al., 2011)
    EndoGI - Ald1
    experimental knowledge based
    (Guruharsha et al., 2011)
    EndoGI - AnxB10
    experimental knowledge based
    (Guruharsha et al., 2011)
    EndoGI - CG10638
    experimental knowledge based
    (Guruharsha et al., 2011)
    EndoGI - CG10863
    experimental knowledge based
    (Guruharsha et al., 2011)
    EndoGI - CG14062
    experimental knowledge based
    (Guruharsha et al., 2011)
    EndoGI - CG14715
    experimental knowledge based
    (Guruharsha et al., 2011)
    EndoGI - CG17778
    two hybrid
    (Hu et al., 2017.6.13)
    EndoGI - CG2852
    experimental knowledge based
    (Guruharsha et al., 2011)
    EndoGI - CG5174
    experimental knowledge based
    (Guruharsha et al., 2011)
    EndoGI - CG6709
    two hybrid
    (Hu et al., 2017.6.13)
    EndoGI - Calr
    experimental knowledge based
    (Guruharsha et al., 2011)
    EndoGI - Diap2
    experimental knowledge based
    (Guruharsha et al., 2011)
    EndoGI - EndoG
    enzymatic study, autoradiography, experimental knowledge based, cosedimentation, molecular weight
    (Guruharsha et al., 2011, Temme et al., 2009)
    EndoGI - Eno
    experimental knowledge based
    (Guruharsha et al., 2011)
    EndoGI - Fkbp14
    experimental knowledge based
    (Guruharsha et al., 2011)
    EndoGI - GILT2
    two hybrid
    (Hu et al., 2017.6.13)
    EndoGI - Gdi
    experimental knowledge based
    (Guruharsha et al., 2011)
    EndoGI - Glo1
    experimental knowledge based
    (Guruharsha et al., 2011)
    EndoGI - GstO3
    experimental knowledge based
    (Guruharsha et al., 2011)
    EndoGI - HINT1
    experimental knowledge based
    (Guruharsha et al., 2011)
    EndoGI - Hsc70Cb
    experimental knowledge based
    (Guruharsha et al., 2011)
    EndoGI - Inos
    experimental knowledge based
    (Guruharsha et al., 2011)
    EndoGI - Mdh2
    experimental knowledge based
    (Guruharsha et al., 2011)
    EndoGI - Moe
    experimental knowledge based
    (Guruharsha et al., 2011)
    EndoGI - Nacα
    experimental knowledge based
    (Guruharsha et al., 2011)
    EndoGI - Nlp
    experimental knowledge based
    (Guruharsha et al., 2011)
    EndoGI - PHGPx
    experimental knowledge based
    (Guruharsha et al., 2011)
    EndoGI - Paics
    two hybrid
    (Hu et al., 2017.6.13)
    EndoGI - Pgd
    experimental knowledge based
    (Guruharsha et al., 2011)
    EndoGI - Prx2540-2
    experimental knowledge based
    (Guruharsha et al., 2011)
    EndoGI - Sh3β
    experimental knowledge based
    (Guruharsha et al., 2011)
    EndoGI - Stip1
    experimental knowledge based
    (Guruharsha et al., 2011)
    EndoGI - Uch
    experimental knowledge based
    (Guruharsha et al., 2011)
    EndoGI - awd
    experimental knowledge based
    (Guruharsha et al., 2011)
    EndoGI - capt
    experimental knowledge based
    (Guruharsha et al., 2011)
    EndoGI - cib
    experimental knowledge based
    (Guruharsha et al., 2011)
    EndoGI - fabp
    experimental knowledge based
    (Guruharsha et al., 2011)
    EndoGI - flr
    experimental knowledge based
    (Guruharsha et al., 2011)
    EndoGI - lms
    two hybrid
    (Hu et al., 2017.6.13)
    EndoGI - regucalcin
    experimental knowledge based
    (Guruharsha et al., 2011)
    EndoGI - scf
    experimental knowledge based
    (Guruharsha et al., 2011)
    EndoGI - scu
    experimental knowledge based
    (Guruharsha et al., 2011)
    EndoGI - sel
    experimental knowledge based
    (Guruharsha et al., 2011)
    EndoGI - yip2
    experimental knowledge based
    (Guruharsha et al., 2011)
    Summary of Genetic Interactions
    esyN Network Diagram
    esyN Network Key:
    Suppression
    Enhancement
    View in Interactions Browser
    Please look at the allele data for full details of the genetic interactions
    Starting gene(s)
    Interaction type
    Interacting gene(s)
    Reference
    EndoGI
    suppressible
    Abl
    (O'Keefe et al., 2011)
    EndoGI
    suppressible
    mam
    (O'Keefe et al., 2011)
    Starting gene(s)
    Interaction type
    Interacting gene(s)
    Reference
    External Data
    Linkouts
    DroID - A comprehensive database of gene and protein interactions.
    MIST (protein-protein) - An integrated Molecular Interaction Database
    Pathways
    Signaling Pathways (FlyBase)
    Positive Regulators of Notch Signaling Pathway -
    The Notch receptor signaling pathway is activated by the binding of the transmembrane receptor Notch (N) to transmembrane ligands, Dl or Ser, presented on adjacent cells. This results in the proteolytic cleavage of N, releasing the intracellular domain (NICD). NICD translocates into the nucleus, interacting with Su(H) and mam to form a transcription complex, which up-regulates transcription of Notch-responsive genes. Positive regulators of the pathway enhance the signal from the sending cell or the response in the receiving cell. (Adapted from FBrf0225731 and FBrf0192604).
    Metabolic Pathways
    External Data
    Linkouts
    Genomic Location and Detailed Mapping Data
    Chromosome (arm)
    2L
    Recombination map
    2-52
    Cytogenetic map
    35F1-35F1
    Sequence location
    FlyBase Computed Cytological Location
    Cytogenetic map
    Evidence for location
    35F1-35F1
    Limits computationally determined from genome sequence between P{lacW}CycEk05007&P{lacW}CycEk02602 and P{EP}crpEP721&P{lacW}crpk07829
    Experimentally Determined Cytological Location
    Cytogenetic map
    Notes
    References
    Experimentally Determined Recombination Data
    Location

    2-52

    (FlyBase, 2016)

    2-49.3

    (Comeron et al., 2012)
    Left of (cM)
    Right of (cM)
    Notes
    Stocks and Reagents
    Stocks (5)
    Genomic Clones (24)
    cDNA Clones (85)
     

    Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

    cDNA clones, fully sequenced
    BDGP DGC clones
    Other clones
      Drosophila Genomics Resource Center cDNA clones

      For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

      cDNA Clones, End Sequenced (ESTs)
      BDGP DGC clones
      Other clones
      RNAi and Array Information
      Linkouts
      DRSC - Results frm RNAi screens
      GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
      Antibody Information
      Laboratory Generated Antibodies
       

      monoclonal

      (O'Keefe et al., 2011)

      polyclonal

      (Temme et al., 2009)
      Commercially Available Antibodies
       
      Other Information
      Relationship to Other Genes
      Source for database identify of

      Source for identity of: BG:DS07473.2 CG4930

      (Kodira, 1999.11)

      Source for identity of: EndoGI CG4930

      (Temme et al., 2009)
      Source for database merge of
      Additional comments
      Other Comments
      Origin and Etymology
      Discoverer
      Etymology
      Identification
      External Crossreferences and Linkouts ( 40 )
      Sequence Crossreferences
      NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.
      GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
      GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
      RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.
      UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information
      Other crossreferences
      Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones
      DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species
      EMBL-EBI Single Cell Expression Atlas - Single cell expression across species
      Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
      FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
      FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data
      Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
      Flygut - An atlas of the Drosophila adult midgut
      GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
      InterPro - A database of protein families, domains and functional sites
      KEGG Genes - Molecular building blocks of life in the genomic space.
      MARRVEL_MODEL - MARRVEL (model organism gene)
      modMine - A data warehouse for the modENCODE project
      Linkouts
      DroID - A comprehensive database of gene and protein interactions.
      DRSC - Results frm RNAi screens
      FlyCyc Genes - Genes from a BioCyc PGDB for Dmel
      FlyMine - An integrated database for Drosophila genomics
      MIST (protein-protein) - An integrated Molecular Interaction Database
      Synonyms and Secondary IDs (6)
      Datasets (0)
      Study focus (0)
      Experimental Role
      Project
      Project Type
      Title
      References (37)