FlyBase Gene Report: Dmel\Ku80

General Information

Symbol

Dmel\Ku80

Species

D. melanogaster

Name

Ku80

Annotation Symbol

CG18801

Feature Type

protein_coding_gene

FlyBase ID

FBgn0041627

Gene Model Status

Current

Stock Availability

4 publicly available

Gene Summary

Ku80 (Ku80) encodes a protein that forms a Ku heterodimer with the product of Irbp, which binds to DNA double-strand break ends and is required for the non-homologous end joining pathway of DNA repair. [Date last reviewed: 2018-11-08] (FlyBase Gene Snapshot)

All Summaries

Gene Snapshot
Alliance
Auto summary
Gene Group
Interactive Fly

Also Known As

BG:DS09217.6

Key Links

Genomic Location

Cytogenetic map

35D4-35D4

Sequence location

2L:15,768,630..15,771,159 [-]

Recombination map

2-51

RefSeq locus

NT_033779 REGION:15768630..15771159

Sequence

Get Decorated FASTA

Genomic Maps

JBrowse GBrowse

Help me choose

Other Genome Views

The following external sites may use different assemblies or annotations than FlyBase.

Function

GO Summary Ribbons

Gene Ontology (GO) Annotations (11 terms)

Molecular Function (4 terms)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (4 terms)

CV Term

Evidence

References

enables ATPase, acting on DNA

inferred from sequence or structural similarity with UniProtKB:P13010

(FlyBase Curators, 2008--)

enables damaged DNA binding

inferred from electronic annotation with InterPro:IPR024193

(assigned by InterPro )

(FlyBase Curators et al., 2004-)

contributes_to double-stranded DNA binding

inferred from biological aspect of ancestor with PANTHER:PTN000288287

(assigned by GO_Central )

(Gaudet et al., 2011)

enables telomeric DNA binding

inferred from biological aspect of ancestor with PANTHER:PTN000288287

(assigned by GO_Central )

(Gaudet et al., 2011)

Biological Process (6 terms)

Terms Based on Experimental Evidence (4 terms)

CV Term

Evidence

References

involved_in cellular response to gamma radiation

inferred from mutant phenotype

(Zhang et al., 2013)

involved_in double-strand break repair via nonhomologous end joining

inferred from mutant phenotype

(Min et al., 2004)

involved_in response to ethanol

inferred from mutant phenotype

(Juraeva et al., 2015)

involved_in telomere maintenance

inferred from mutant phenotype

(Melnikova et al., 2005)

Terms Based on Predictions or Assertions (5 terms)

CV Term

Evidence

References

involved_in cellular response to gamma radiation

inferred from biological aspect of ancestor with PANTHER:PTN000288287

(assigned by GO_Central )

(Gaudet et al., 2011)

involved_in cellular response to X-ray

inferred from biological aspect of ancestor with PANTHER:PTN000288287

(assigned by GO_Central )

(Gaudet et al., 2011)

involved_in DNA recombination

inferred from electronic annotation with InterPro:IPR024193

(assigned by InterPro )

(FlyBase Curators et al., 2004-)

involved_in double-strand break repair via nonhomologous end joining

inferred from biological aspect of ancestor with PANTHER:PTN000288287

(assigned by GO_Central )

(Gaudet et al., 2011)

involved_in telomere maintenance

inferred from biological aspect of ancestor with PANTHER:PTN000288287

(assigned by GO_Central )

(Gaudet et al., 2011)

Cellular Component (1 term)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (1 term)

CV Term

Evidence

References

part_of Ku70:Ku80 complex

inferred from biological aspect of ancestor with PANTHER:PTN000288287

(assigned by GO_Central )

(Gaudet et al., 2011)

Gene Group (FlyBase)

OTHER ATPASES

Protein Family (UniProt)

Protein Signatures (InterPro)

Summaries

Gene Snapshot

Gene Group (FlyBase)

OTHER ATPASES -: The 'other ATPases group comprises ATPases that do not fit into any of the other major ATPase groups.

Gene Model and Products

Number of Transcripts

Number of Unique Polypeptides

Please see the JBrowse view of Dmel\Ku80 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Comments on Gene Model

Low-frequency RNA-Seq exon junction(s) not annotated.

Gene model reviewed during 5.44

Sequence Ontology: Class of Gene

nuclear_gene

protein_coding_gene

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Assoc. CDS (aa)

Ku80-RA

FBtr0080763

NM_135923

2304

699

Additional Transcript Data and Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

RefSeq ID

GenBank

Ku80-PA

FBpp0080322

79.8

699

5.02

NP_609767

AAG22435

Polypeptides with Identical Sequences

There is only one protein coding transcript and one polypeptide associated with this gene

Additional Polypeptide Data and Comments

Reported size (kDa)

Comments

External Data

Crossreferences

InterPro - A database of protein families, domains and functional sites

Linkouts

Sequences Consistent with the Gene Model

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Ku80 using the Feature Mapper tool.

External Data

Crossreferences

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

Ku80_1

Linkouts

Expression Data

Expression Summary Ribbons

Colored tiles in ribbon indicate that expression data has been curated by FlyBase for that anatomical location. Colorless tiles indicate that there is no curated data for that location.

For complete stage-specific expression data, view the modENCODE Development RNA-Seq section under High-Throughput Expression below.

Transcript Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Evidence

References

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

GBrowse - Visual display of RNA-Seq signals

View Dmel\Ku80 in GBrowse 2

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\Ku80

View exonic expression by tissue for Dmel\Ku80

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

DRscDB

34930/tissue=All

EMBL-EBI Single Cell Expression Atlas

FBgn0041627

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

CG18801-RA;CG31826-RA

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG18801

Flygut - An atlas of the Drosophila adult midgut

FBgn0041627

Images

FlyBase Wiki

Image Based Resources

Alleles, Insertions, Transgenic Constructs, and Aberrations

Classical and Insertion Alleles ( 1 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 3 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of Ku80

Transgenic constructs containing regulatory region of Ku80

Aberrations (Deficiencies and Duplications) ( 1 )

Inferred from experimentation ( 1 )

Gene disrupted in

Df(2L)Exel6037

(Ryder, 2004.4.26)

Inferred from location ( 0 )

Alleles Representing Disease-Implicated Variants

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

viable, with Dcr-2^UAS.cDa, Scer\GAL4^elav.PLu

Ku80^GD1712

viable, with Scer\GAL4^Mef2.PR

Ku80^GD1712

viable, with Scer\GAL4^pnr-MD237

Ku80^GD1712

viable, with Scer\GAL4^tin.CΔ4

Ku80^GD1712

Other Phenotypes

Allele

chemical resistant, with Scer\GAL4^Appl.PU

Ku80^JF02790

short lived | heat sensitive, with Scer\GAL4^tin.CΔ4

Ku80^GD1712

Phenotype manifest in

Allele

Orthologs

Downloads

Download All DIOPT Orthologs

Download All OrthoDB Orthologs

Human Orthologs (via DIOPT v8.0)

Homo sapiens (Human) (13)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Hsap\XRCC5

13 of 15

Yes

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

Model Organism Orthologs (via DIOPT v8.0)

Mus musculus (laboratory mouse) (11)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Mmus\Xrcc5

12 of 15

Yes

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

Rattus norvegicus (Norway rat) (10)

Rnor\Xrcc5

8 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Xenopus tropicalis (Western clawed frog) (10)

Xtro\xrcc5

5 of 12

Yes

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

Danio rerio (Zebrafish) (9)

Drer\xrcc5

8 of 15

Yes

Drer\LOC110438490

2 of 15

Yes

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

Caenorhabditis elegans (Nematode, roundworm) (13)

Cele\cku-80

8 of 15

Yes

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

Arabidopsis thaliana (thale-cress) (1)

Atha\KU80

6 of 9

Yes

Saccharomyces cerevisiae (Brewer's yeast) (4)

Scer\YKU80

7 of 15

Yes

Scer\SEC14

1 of 15

Scer\SFH5

1 of 15

Scer\YKL091C

1 of 15

Schizosaccharomyces pombe (Fission yeast) (1)

Spom\pku80

7 of 12

Yes

Ortholog(s) in Drosophila Species (via OrthoDB v9.1) ( EOG0919065E )

Organism

Common Name

Gene

AAA Syntenic Ortholog

Multiple Dmel Genes in this Orthologous Group

Drosophila suzukii

Spotted wing Drosophila

Drosophila simulans

Drosophila sechellia

Drosophila erecta

Drosophila yakuba

Drosophila ananassae

Drosophila pseudoobscura pseudoobscura

Dpse\GA15084

Drosophila persimilis

Dper\GL15436

Drosophila willistoni

Dwil\GK24271

Drosophila virilis

Dvir\GJ18003

Drosophila mojavensis

Dmoj\GI17244

Drosophila grimshawi

Dgri\GH13494

Orthologs in non-Drosophila Dipterans (via OrthoDB v9.1) ( EOG0915075C )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Musca domestica

House fly

Mdoa\17017791

Glossina morsitans

Tsetse fly

Gmor\GMOY007186

Lucilia cuprina

Australian sheep blowfly

Lcup\FF38_03895

Mayetiola destructor

Hessian fly

Mdes\Mdes010971

Mayetiola destructor

Hessian fly

Mdes\Mdes005135

Aedes aegypti

Yellow fever mosquito

Aaeg\AAEL003684

Anopheles darlingi

American malaria mosquito

Adar\ADAC002379

Anopheles gambiae

Malaria mosquito

Agam\AGAP009910

Culex quinquefasciatus

Southern house mosquito

Cqui\CPIJ011452

Orthologs in non-Dipteran Insects (via OrthoDB v9.1) ( EOG090W0N5D )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Danaus plexippus

Monarch butterfly

Dple\DPOGS204693-PA

Heliconius melpomene

Postman butterfly

Hmel\HMEL008253

Apis florea

Little honeybee

Aflo\3294660788

Apis mellifera

Western honey bee

Amel\LOC552750

Bombus impatiens

Common eastern bumble bee

Bimp\BIMP15240

Bombus terrestris

Buff-tailed bumblebee

Bter\15208674

Linepithema humile

Argentine ant

Lhum\LH18130

Megachile rotundata

Alfalfa leafcutting bee

Mrot\MROTU:002e1a

Nasonia vitripennis

Parasitic wasp

Nvit\Nasvi2EG007880

Dendroctonus ponderosae

Mountain pine beetle

Dpod\YQE_12618

Pediculus humanus

Human body louse

Phum\PHUM529370

Rhodnius prolixus

Kissing bug

Rpro\RPRC012409

Acyrthosiphon pisum

Pea aphid

Apim\ACYPI001555

Acyrthosiphon pisum

Pea aphid

Apim\ACYPI070246

Acyrthosiphon pisum

Pea aphid

Apim\ACYPI41812

Acyrthosiphon pisum

Pea aphid

Apim\ACYPI086733

Acyrthosiphon pisum

Pea aphid

Apim\ACYPI068626

Acyrthosiphon pisum

Pea aphid

Apim\ACYPI081313

Zootermopsis nevadensis

Nevada dampwood termite

Znev\Znev_05675

Orthologs in non-Insect Arthropods (via OrthoDB v9.1) ( EOG090X0NED )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Ixodes scapularis

Black-legged tick

Isca\ISCW017702

Stegodyphus mimosarum

African social velvet spider

Smim\KFM64580.1

Tetranychus urticae

Two-spotted spider mite

Turt\tetur15g03380

Tetranychus urticae

Two-spotted spider mite

Turt\tetur08g05290

Orthologs in non-Arthropod Metazoa (via OrthoDB v9.1) ( EOG091G11VD )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Strongylocentrotus purpuratus

Purple sea urchin

Spur\Sp-Bmp5-8

Strongylocentrotus purpuratus

Purple sea urchin

Spur\Sp-Ku86l

Ciona intestinalis

Vase tunicate

Cint\zf(c2h2)-102

Gallus gallus

Domestic chicken

Ggal\XRCC5

Paralogs

Downloads

Download All DIOPT Paralogs

Paralogs (via DIOPT v8.0)

Drosophila melanogaster (Fruit fly) (29)

Gene Symbol

Score

Source

Alignment

3 of 10

2 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

Human Disease Associations

FlyBase Human Disease Model Reports

alcohol, response to, XRCC5-related

Disease Model Summary Ribbon

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 1 )

Allele

Disease

Evidence

References

Ku80^JF02790

model of alcohol dependence

CEA

(Juraeva et al., 2015)

Potential Models Based on Orthology ( 0 )

Human Ortholog

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Allele

Disease

Interaction

References

Disease Associations of Human Orthologs (via DIOPT v8.0 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

XRCC5; X-ray repair cross complementing 5

13 of 15

194364

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

esyN Network Diagram

Interactions Browser

View in Interactions Browser

Please see the Physical Interaction reports below for full details

protein-protein

Physical Interaction

Assay

References

Ku80 - CG15047

experimental knowledge based

(Guruharsha et al., 2011)

Ku80 - CG3548

experimental knowledge based

(Guruharsha et al., 2011)

Ku80 - CG8142

experimental knowledge based

(Guruharsha et al., 2011)

Ku80 - DNAlig4

experimental knowledge based

(Guruharsha et al., 2011)

Ku80 - Gnf1

experimental knowledge based

(Guruharsha et al., 2011)

Ku80 - Irbp

experimental knowledge based

(Guruharsha et al., 2011)

Ku80 - Parp

experimental knowledge based

(Guruharsha et al., 2011)

Ku80 - RPA2

experimental knowledge based

(Guruharsha et al., 2011)

Ku80 - RPA3

experimental knowledge based

(Guruharsha et al., 2011)

Ku80 - RfC3

experimental knowledge based

(Guruharsha et al., 2011)

Ku80 - RfC38

experimental knowledge based

(Guruharsha et al., 2011)

Ku80 - RfC4

experimental knowledge based

(Guruharsha et al., 2011)

Ku80 - RpA-70

experimental knowledge based

(Guruharsha et al., 2011)

Ku80 - TFAM

experimental knowledge based

(Guruharsha et al., 2011)

Ku80 - TfAP-2

experimental knowledge based

(Guruharsha et al., 2011)

Ku80 - Xpc

experimental knowledge based

(Guruharsha et al., 2011)

Ku80 - al

experimental knowledge based

(Guruharsha et al., 2011)

Ku80 - hbn

experimental knowledge based

(Guruharsha et al., 2011)

Ku80 - otp

anti tag coimmunoprecipitation, peptide massfingerprinting, experimental knowledge based

(Rhee et al., 2014)

Ku80 - tll

experimental knowledge based

(Guruharsha et al., 2011)

Ku80 - ttk

experimental knowledge based

(Guruharsha et al., 2011)

Summary of Genetic Interactions

esyN Network Diagram

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

External Data

Linkouts

BioGRID - A database of protein and genetic interactions.

60943

DroID - A comprehensive database of gene and protein interactions.

FBgn0041627

InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.

34930

MIST (protein-protein) - An integrated Molecular Interaction Database

Ku80

Pathways

Signaling Pathways (FlyBase)

Metabolic Pathways

External Data

Linkouts

KEGG Pathways - Wiring diagrams of molecular interactions, reactions and relations.

Non-homologous end-joining

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

Genomic Location and Detailed Mapping Data

Chromosome (arm)

Recombination map

2-51

Cytogenetic map

35D4-35D4

Sequence location

2L:15,768,630..15,771,159 [-]

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

35D4-35D4

Limits computationally determined from genome sequence between P{lacW}CycE^k05007&P{lacW}CycE^k02602 and P{EP}crp^EP721&P{lacW}crp^k07829

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

2-51

(FlyBase, 2016)

2-48.9

(Comeron et al., 2012)

Left of (cM)

Right of (cM)

Notes

Stocks and Reagents

Stocks (4)

Bloomington

27710

y¹ v¹; P{TRiP.JF02790}attP2

62513

y¹ v¹; P{TRiP.HMJ24057}attP40/CyO

VDRC

v37110

w¹¹¹⁸; P{GD1712}v37110

v37111

w¹¹¹⁸; P{GD1712}v37111

Genomic Clones (19)

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (37)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced

BDGP DGC clones

AT19081

Other clones

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

FBgn0041627

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

RNAi and Array Information

Linkouts

DRSC - Results frm RNAi screens

FBgn0041627

GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents

34930

Antibody Information

Laboratory Generated Antibodies

monoclonal

(Harpprecht et al., 2019)

polyclonal

(Chiolo et al., 2011)

Commercially Available Antibodies

Other Information

Relationship to Other Genes

Source for database identify of

Source for database merge of

Source for merge of: Ku80 CG18801

(FlyBase, 1996-)

Additional comments

" BG:DS09217.4 " and " BG:DS09217.6 " probably correspond to "l(2)35De" and "l(2)35Dh", but the available data cannot determine which is which.

(Ashburner et al., 1999)

" BG:DS09217.6 " could correspond to "l(2)35Di", "l(2)35De" or "l(2)35Dh".

(Ashburner et al., 1999.10.12)

Source for merge of Ku80 CG18801 was sequence comparison ( date:001216 ).

(FlyBase, 1996-)

Other Comments

Ku80 has a role in length regulation of telomeres.

(Melnikova et al., 2005)

A decrease in Ku80 gene dosage causes a sharp increase in the frequency of HeT-A and TART-element attachments to a broken chromosome end and strongly enhances terminal DNA elongation by gene conversion.

(Melnikova et al., 2005)

Origin and Etymology

Discoverer

Etymology

Identification

External Crossreferences and Linkouts ( 40 )

Sequence Crossreferences

NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.

34930

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.

RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.

UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information

Other crossreferences

Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones

FBgn0041627

DRscDB

34930/tissue=All

EMBL-EBI Single Cell Expression Atlas

FBgn0041627

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

Ku80_1

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG18801

Flygut - An atlas of the Drosophila adult midgut

FBgn0041627

GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents

34930

InterPro - A database of protein families, domains and functional sites

KEGG Genes - Molecular building blocks of life in the genomic space.

Dmel_CG18801

MARRVEL_MODEL

34930

modMine - A data warehouse for the modENCODE project

FBgn0041627

Linkouts

BioGRID - A database of protein and genetic interactions.

60943

DroID - A comprehensive database of gene and protein interactions.

FBgn0041627

DRSC - Results frm RNAi screens

FBgn0041627

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

CG18801-RA;CG31826-RA

FlyCyc Genes - Genes from a BioCyc PGDB for Dmel

FBGN0041627

FlyMine - An integrated database for Drosophila genomics

FBgn0041627

InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.

34930

KEGG Pathways - Wiring diagrams of molecular interactions, reactions and relations.

Non-homologous end-joining

MIST (protein-protein) - An integrated Molecular Interaction Database

Ku80

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

Synonyms and Secondary IDs (7)

Reported As

Symbol Synonym

BG:DS09217.6

(Ashburner et al., 1999, Ashburner et al., 1999, Ashburner et al., 1999, Ashburner et al., 1999.10.12)

CG18801

(Hosono et al., 2015, Perkins et al., 2009)

DmKu80

(Min et al., 2004)

KU80

(Mason et al., 2004)

(Boutanaev et al., 2007)

ku80

(Vicars et al., 2021, Drelon et al., 2018, Mishra et al., 2013, Zhang et al., 2013, Chen et al., 2011, Zhang et al., 2008)

Name Synonyms

Ku80

Secondary FlyBase IDs

FBgn0028843
FBgn0042128

Datasets (0)

Study focus (0)

Experimental Role

Project

Project Type

Title

References (76)

Report Sections

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