FlyBase Gene Report: Dmel\β3GalTII

General Information

Symbol

Dmel\β3GalTII

Species

D. melanogaster

Name

β-1,3-Galactosyltransferase II

Annotation Symbol

CG8734

Feature Type

protein_coding_gene

FlyBase ID

FBgn0033315

Gene Model Status

Current

Stock Availability

5 publicly available

Enzyme Name (EC)

galactosylxylosylprotein 3-beta-galactosyltransferase (2.4.1.134)

Gene Summary

β-1,3-Galactosyltransferase II (β3GalTII) encodes an enzyme that catalyzes the transfer of glactose to the acceptor galactose during the synthesis of the tetrasaccharide linker of the glycosaminoglycan side chain of proteoglycans. The tetrasaccharide linker is common to heparan sulfate and chondoritin sulfate proteoglycans. [Date last reviewed: 2019-03-21] (FlyBase Gene Snapshot)

All Summaries

Gene Snapshot
Alliance
Auto summary
Gene Group
Interactive Fly

Also Known As

Galactosyltransferase II

Key Links

Genomic Location

Cytogenetic map

44D5-44D5

Sequence location

2R:8,626,181..8,627,611 [-]

Recombination map

2-59

RefSeq locus

NT_033778 REGION:8626181..8627611

Sequence

Get Decorated FASTA

Genomic Maps

JBrowse

Other Genome Views

The following external sites may use different assemblies or annotations than FlyBase.

Function

Gene Ontology (GO) Annotations (9 terms)

Molecular Function (2 terms)

Terms Based on Experimental Evidence (1 term)

CV Term

Evidence

References

enables galactosylxylosylprotein 3-beta-galactosyltransferase activity

inferred from direct assay

(Ueyama et al., 2008)

Terms Based on Predictions or Assertions (2 terms)

CV Term

Evidence

References

enables galactosylxylosylprotein 3-beta-galactosyltransferase activity

inferred from biological aspect of ancestor with PANTHER:PTN000880300

(GO Reference Genome Project, 2011-)

enables hexosyltransferase activity

inferred from electronic annotation with InterPro:IPR002659

(InterPro Project Members, 2004-)

Biological Process (5 terms)

Terms Based on Experimental Evidence (2 terms)

CV Term

Evidence

References

involved_in glycosaminoglycan-protein linkage region biosynthetic process

inferred from genetic interaction with FLYBASE:β4GalT7; FB:FBgn0039258

(Ueyama et al., 2008)

involved_in heparan sulfate proteoglycan biosynthetic process

inferred from mutant phenotype

(Ueyama et al., 2008)

inferred from genetic interaction with FLYBASE:Oxt; FB:FBgn0015360

(Ueyama et al., 2008)

inferred from genetic interaction with FLYBASE:Papss; FB:FBgn0020389

(Ueyama et al., 2008)

inferred from genetic interaction with FLYBASE:sotv; FB:FBgn0029175

(Ueyama et al., 2008)

inferred from genetic interaction with FLYBASE:Hs3st-B; FB:FBgn0031005

(Ueyama et al., 2008)

inferred from genetic interaction with FLYBASE:Hs6st; FB:FBgn0038755

(Ueyama et al., 2008)

inferred from genetic interaction with FLYBASE:ttv; FB:FBgn0265974

(Ueyama et al., 2008)

Terms Based on Predictions or Assertions (3 terms)

CV Term

Evidence

References

involved_in chondroitin sulfate proteoglycan biosynthetic process

inferred from sequence or structural similarity with UniProtKB:Q96L58

(Gene Ontology Curators, 2002-)

involved_in glycoprotein biosynthetic process

inferred from electronic annotation with InterPro:IPR002659

(InterPro Project Members, 2004-)

involved_in glycosaminoglycan biosynthetic process

inferred from biological aspect of ancestor with PANTHER:PTN000880300

(GO Reference Genome Project, 2011-)

Cellular Component (2 terms)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (2 terms)

CV Term

Evidence

References

is_active_in Golgi membrane

inferred from biological aspect of ancestor with PANTHER:PTN000130249

(GO Reference Genome Project, 2011-)

located_in Golgi membrane

inferred from sequence or structural similarity with UniProtKB:O54904

(Gene Ontology Curators, 2002-)

located_in membrane

inferred from electronic annotation with InterPro:IPR002659

(InterPro Project Members, 2004-)

Gene Group (FlyBase)

UNCLASSIFIED GALACTOSYLTRANSFERASES

Pathway (FlyBase)

CHONDROITIN SULFATE PROTEOGLYCAN BIOSYNTHESIS

HEPARAN SULFATE PROTEOGLYCAN BIOSYNTHESIS

Protein Family (UniProt)

Protein Signatures (InterPro)

Glycosyl transferase, family 31

Catalytic Activity (EC/Rhea)

galactosylxylosylprotein 3-beta-galactosyltransferase activity

3-O-(beta-D-galactosyl-(1->4)-beta-D-xylosyl)-L-seryl-[protein] + UDP- alpha-D-galactose = 3-O-(beta-D-galactosyl-(1->3)-beta-D-galactosyl- (1->4)-beta-D-xylosyl)-L-seryl-[protein] + UDP + H(+) (2.4.1.134)

RHEA 11780:

Summaries

Gene Snapshot

Gene Group (FlyBase)

UNCLASSIFIED GALACTOSYLTRANSFERASES -: This group comprises galactosyltransferases that do not classify under other groups in FlyBase.

Pathway (FlyBase)

CHONDROITIN SULFATE PROTEOGLYCAN BIOSYNTHESIS -: Chondroitin sulfate proteoglycans (CSPGs) are glycoconjugates that consist of a core protein linked to one or more linear chondroitin sulfate (CS) chains. The chains are composed of alternating glucuronic acid and N-acetylgalactosamine that can be variably O-sulfated. CS synthesis occurs in the Golgi apparatus. It starts with the formation of a tetrasaccharide linker on the core protein followed by the alternating addition of glucuronic acid and N-acetylgalactosamine residues, the latter of which can be O-sulfated. CSPGs are then transported to the plasma membrane. D. melanogaster produces two types of CSPGs: one bearing 4-O-sulfated chondroitin and another with non-sulfated chondroitin. (Adapted from PMID:23774590 and FBrf0228609.)
HEPARAN SULFATE PROTEOGLYCAN BIOSYNTHESIS -: Heparan sulfate proteoglycans (HSPGs) are glycoconjugates that consist of a core protein linked to one or more linear heparan sulfate (HS) chains. The chains are composed of alternating N-acetyl-D-glucosamine and glucuronic acid or iduronic acid that can be variably N- and O-sulfated. HS synthesis occurs in the Golgi apparatus. It starts with the formation of a tetrasaccharide linker on the core protein followed by the alternating addition of glucuronic acid and N-acetylglucosamine residues. Glucuronic acid can undergo epimerization into iduronic acid, which together with N-acetylglucosamine residues, can be sulfated. HSPGs are then transported to the plasma membrane where they can be processed further by endosulfatases such as Sulf1 that remove sulfate groups from specific sites. (Adapted from FBrf0232460 and FBrf0228609.)

Gene Model and Products

Number of Transcripts

Number of Unique Polypeptides

Please see the JBrowse view of Dmel\β3GalTII for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Structure

Protein 3D structure (Predicted by AlphaFold) (AlphaFold entry A1Z7G9)

If you don't see a structure in the viewer, refresh your browser.

Model Confidence:

Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)

AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Experimentally Determined Structures

Crossreferences

Comments on Gene Model

Gene model reviewed during 5.43

Gene model reviewed during 5.49

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Assoc. CDS (aa)

β3GalTII-RA

FBtr0088728

NM_136555

1431

382

Additional Transcript Data and Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

UniProt

RefSeq ID

GenBank

β3GalTII-PA

FBpp0087807

44.4

382

9.20

A1Z7G9

NP_610399

AAF59065

Polypeptides with Identical Sequences

There is only one protein coding transcript and one polypeptide associated with this gene

Additional Polypeptide Data and Comments

Reported size (kDa)

Comments

External Data

Crossreferences

InterPro - A database of protein families, domains and functional sites

Glycosyl transferase, family 31

Linkouts

Sequences Consistent with the Gene Model

Nucleotide / Polypeptide Records

UniProt

A1Z7G9

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\β3GalTII using the Feature Mapper tool.

External Data

Crossreferences

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

beta3GalTII_1

Linkouts

Expression Data

Testis-specificity index

The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).

0.83

Transcript Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Evidence

References

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

JBrowse - Visual display of RNA-Seq signals

View Dmel\β3GalTII in JBrowse

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\β3GalTII

View exonic expression by tissue for Dmel\β3GalTII

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

35848/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0033315

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0033315

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0033315

Flygut - An atlas of the Drosophila adult midgut

FBgn0033315

Images

FlyBase Wiki

Image Based Resources

Alleles, Insertions, Transgenic Constructs, and Aberrations

Classical and Insertion Alleles ( 1 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 6 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of β3GalTII

Transgenic constructs containing regulatory region of β3GalTII

Aberrations (Deficiencies and Duplications) ( 1 )

Inferred from experimentation ( 1 )

Gene disrupted in

Df(2R)Exel8047

(Ryder, 2004.4.26)

Inferred from location ( 4 )

Variants

Variant Molecular Consequences

Alleles Representing Disease-Implicated Variants

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

lethal, with Scer\GAL4^Act5C.PU

β3GalTII^RNAi.UAS.cYa

viable, with Scer\GAL4^pnr-MD237

β3GalTII^GD1876

viable, with Scer\GAL4^tin.CΔ4

β3GalTII^GD1876

Other Phenotypes

Allele

flightless, with Scer\GAL4^Mef2.PR

β3GalTII^GD1876

visible, with Scer\GAL4^ap-md544

β3GalTII^RNAi.UAS

visible, with Scer\GAL4^GMR.PS

β3GalTII^RNAi.UAS

Phenotype manifest in

Allele

eye, with Scer\GAL4^GMR.PS

β3GalTII^RNAi.UAS

interommatidial bristle, with Scer\GAL4^GMR.PS

β3GalTII^RNAi.UAS

wing, with Scer\GAL4^ap-md544

β3GalTII^RNAi.UAS

wing vein | ectopic, with Scer\GAL4^en-e16E

β3GalTII^RNAi.UAS.cYa

Orthologs

Downloads

Download All DIOPT Orthologs

Human Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Homo sapiens (Human) (15)

Hsap\B3GALT6

14 of 14

Yes

2 of 14

2 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Model Organism Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Rattus norvegicus (Norway rat) (14)

Rnor\B3galt6

14 of 14

Yes

2 of 14

2 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Mus musculus (laboratory mouse) (15)

Mmus\B3galt6

13 of 14

Yes

2 of 14

2 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Xenopus tropicalis (Western clawed frog) (16)

Xtro\b3galt6

11 of 13

Yes

Xtro\b3galnt2

2 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Yes

Xtro\LOC101732799

1 of 13

Xtro\LOC101734599

1 of 13

Xtro\XB5969542

1 of 13

Danio rerio (Zebrafish) (27)

Drer\b3galt6

14 of 14

Yes

2 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Drer\si:dkey-160o24.3

1 of 14

Drer\si:dkeyp-98a7.1

1 of 14

Drer\zgc:162952

1 of 14

Caenorhabditis elegans (Nematode, roundworm) (11)

Cele\sqv-2

14 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Anopheles gambiae (African malaria mosquito) (6)

Agam\AgaP_AGAP009175

12 of 12

Yes

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

Arabidopsis thaliana (thale-cress) (21)

Atha\AT1G11730

6 of 13

Yes

Atha\DD46

6 of 13

Yes

Atha\AT1G05170

5 of 13

Yes

Atha\AT1G32930

5 of 13

Yes

Atha\AT1G33430

5 of 13

Yes

Atha\AT1G53290

5 of 13

Yes

Atha\AT1G77810

5 of 13

Yes

Atha\AT2G25300

5 of 13

Yes

Atha\AT2G32430

5 of 13

Yes

Atha\AT3G14960

5 of 13

Yes

Atha\AT4G26940

5 of 13

Yes

Atha\AT4G32120

5 of 13

Yes

Atha\AT5G53340

5 of 13

Yes

Atha\AT2G26100

4 of 13

Yes

Atha\AT5G57500

3 of 13

Yes

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

Saccharomyces cerevisiae (Brewer's yeast) (0)

Schizosaccharomyces pombe (Fission yeast) (1)

Spom\pvg3

1 of 12

Yes

Escherichia coli (enterobacterium) (0)

Other Organism Orthologs (via OrthoDB)

Data provided directly from OrthoDB:β3GalTII. Refer to their site for version information.

Paralogs

Downloads

Download All DIOPT Paralogs

Paralogs (via DIOPT v9.1)

Gene Symbol

Score

Source

Alignment

Drosophila melanogaster (Fruit fly) (9)

brn

3 of 13

3 of 13

3 of 13

3 of 13

3 of 13

3 of 13

2 of 13

2 of 13

1 of 13

Human Disease Associations

FlyBase Human Disease Model Reports

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Allele

Disease

Evidence

References

Potential Models Based on Orthology ( 2 )

Human Ortholog

Disease

Evidence

References

B3GALT6; beta-1,3-galactosyltransferase 6

model of Ehlers-Danlos syndrome spondylodysplastic type 2

IEA

(FlyBase, 2019-)

model of spondyloepimetaphyseal dysplasia with joint laxity type 1

IEA

(FlyBase, 2019-)

Modifiers Based on Experimental Evidence ( 0 )

Allele

Disease

Interaction

References

Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

B3GALT6; beta-1,3-galactosyltransferase 6

14 of 14

615291

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

Interaction Browsers

Summary of Genetic Interactions

Interaction Browsers

View in FlyBase Interactions Browser View in MIST tool (external link)

Please look at the allele data for full details of the genetic interactions

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

β3GalTII

enhanceable

Hs3st-B

(Ueyama et al., 2008)

β3GalTII

enhanceable

Hs6st

(Ueyama et al., 2008)

β3GalTII

enhanceable

Oxt

(Ueyama et al., 2008)

β3GalTII

enhanceable

Papss

(Ueyama et al., 2008)

β3GalTII

enhanceable

ttv

(Ueyama et al., 2008)

β3GalTII

enhanceable

β4GalT7

(Ueyama et al., 2008)

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Hs3st-B

enhanceable

β3GalTII

(Ueyama et al., 2008)

Hs6st

enhanceable

β3GalTII

(Ueyama et al., 2008)

Oxt

enhanceable

β3GalTII

(Ueyama et al., 2008)

Papss

enhanceable

β3GalTII

(Ueyama et al., 2008)

ttv

enhanceable

β3GalTII

(Ueyama et al., 2008)

β4GalT7

enhanceable

β3GalTII

(Ueyama et al., 2008)

External Data

Linkouts

DroID - A comprehensive database of gene and protein interactions.

FBgn0033315

Pathways

Signaling Pathways (FlyBase)

Metabolic Pathways

FlyBase

CHONDROITIN SULFATE PROTEOGLYCAN BIOSYNTHESIS
HEPARAN SULFATE PROTEOGLYCAN BIOSYNTHESIS

External Links

FlyCyc Pathways - Pathways from a BioCyc PGDB for Dmel

KEGG Metabolic Pathways - A collection of manually drawn metabolic pathway maps representing knowledge of molecular interaction, reaction and relation networks.

Reactome Metabolic Pathways - An open-source, open access, manually curated and peer-reviewed metabolic pathway database.

A tetrasaccharide linker sequence is required for GAG synthesis

External Data

Linkouts

KEGG Pathways - A collection of manually drawn pathway maps representing knowledge of molecular interaction, reaction and relation networks.

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

A tetrasaccharide linker sequence is required for GAG synthesis

Class of Gene

nuclear_gene

protein_coding_gene

Genomic Location and Detailed Mapping Data

Chromosome (arm)

Recombination map

2-59

Cytogenetic map

44D5-44D5

Sequence location

2R:8,626,181..8,627,611 [-]

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

44D5-44D5

Limits computationally determined from genome sequence between P{lacW}Vps25^k08904&P{lacW}ptc^k02507 and P{PZ}l(2)44DEa⁰⁵⁸⁴⁷

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

2-59

(FlyBase, 2016)

2-57.8

(Comeron et al., 2012)

Left of (cM)

Right of (cM)

Notes

Stocks and Reagents

Stocks (5)

Aberrations including deletions of this gene Aberrations including duplications of this gene

Bloomington

31562

y¹ v¹; P{TRiP.JF01134}attP2

21314

y¹ w^67c23; P{wHy}β3GalTII^DG30308

NIG-Fly

2RG-0901

y² VhaAC39-1^cho-1 v¹; P{U6-β3GalTII.NIG.sgRNA}attP40/CyO

VDRC

v106134

P{KK102749}VIE-260B

v7949

w¹¹¹⁸; P{GD1876}v7949/TM3

Genomic Clones (14)

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (6)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced

BDGP DGC clones

Other clones

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

FBgn0033315

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi and Array Information

Linkouts

DRSC - Results frm RNAi screens

FBgn0033315

Antibody Information

Laboratory Generated Antibodies

Commercially Available Antibodies

Cell Line Information

Publicly Available Cell Lines

Other Stable Cell Lines

Other Comments

Relationship to Other Genes

Source for database merge of

Additional comments

Nomenclature History

Source for database identify of

Source for identity of: β3GalTII CG8734

(Ueyama et al., 2008)

Nomenclature comments

Etymology

Synonyms and Secondary IDs (7)

Reported As

Symbol Synonym

CG8734

(National Institute of Genetics Fly Stocks, 2022-, Caizzi et al., 2016, Yamamoto-Hino et al., 2015, Keleman et al., 2009.8.5, Ni et al., 2008, Ueyama et al., 2008, Häcker et al., 2005)

GalTII

(Bornemann et al., 2008)

dGAGβ3GalTII

(Yamamoto-Hino et al., 2015)

dβ3GalTII

(Ueyama et al., 2008)

β3GalTII

Name Synonyms

CG8734

Galactosyltransferase II

(Bornemann et al., 2008)

β-1,3-Galactosyltransferase II

Secondary FlyBase IDs

Datasets (0)

Study focus (0)

Experimental Role

Project

Project Type

Title

Study result (0)

Result

Result Type

Title

External Crossreferences and Linkouts ( 34 )

Sequence Crossreferences

NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.

35848

GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.

AAF59065

RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.

UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.

A1Z7G9

UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information

A1Z7G9

Other crossreferences

AlphaFold DB - AlphaFold provides open access to protein structure predictions for the human proteome and other key proteins of interest, to accelerate scientific research.

A1Z7G9

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

35848/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0033315

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0033315

FlyMine - An integrated database for Drosophila genomics

FBgn0033315

InterPro - A database of protein families, domains and functional sites

Glycosyl transferase, family 31

KEGG Genes - Molecular building blocks of life in the genomic space.

dme:Dmel_CG8734

MARRVEL_MODEL - MARRVEL (model organism gene)

35848

Linkouts

Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones

FBgn0033315

DroID - A comprehensive database of gene and protein interactions.

FBgn0033315

DRSC - Results frm RNAi screens

FBgn0033315

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

beta3GalTII_1

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0033315

FlyCyc Genes - Genes from a BioCyc PGDB for Dmel

FBGN0033315

FlyCyc Pathways - Pathways from a BioCyc PGDB for Dmel

Flygut - An atlas of the Drosophila adult midgut

FBgn0033315

FlyMet - A comprehensive tissue-specific metabolomics resource for Drosophila.

FBgn0033315

iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)

TC014260

KEGG Metabolic Pathways - A collection of manually drawn metabolic pathway maps representing knowledge of molecular interaction, reaction and relation networks.

KEGG Pathways - A collection of manually drawn pathway maps representing knowledge of molecular interaction, reaction and relation networks.

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

A tetrasaccharide linker sequence is required for GAG synthesis

Reactome Metabolic Pathways - An open-source, open access, manually curated and peer-reviewed metabolic pathway database.

A tetrasaccharide linker sequence is required for GAG synthesis

References (36)

The following external sites may use different assemblies or annotations than FlyBase.

0.83

Report Sections