secreted ligand-binding protein - A mutant has aberrant locomotor activity and dies rapidly in response to starvation, indicating a link between locomotor activity, survival, and food status
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.49
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\to using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\to in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
to is present in the haemolymph of adult males but not females and acts as a secreted protein.
to is required for normal levels of male courtship behaviour and might have a role in integrating information about the organism's sex, nutritional status, and circadian cycle to affect male behaviour.
Shows particularly robust cycling of transcription in adult heads, as assessed by expression analysis using high density oligonucleotide arrays with probe generated during three 12-point time course experiments over the course of 6 days. Shows significant change of expression pattern in circadian mutant background; increased expression in per01, tim01 and decreased expression in ClkJrk background.
Identified as a gene with significant level of mRNA cycling as assessed by expression analysis using high density oligonucleotide arrays with probe generated from adult heads harvested over six time points over the course of a day.
to may participate in a novel circadian output pathway that conveys temporal and food status information to feeding-relevant metabolisms and activity.