FB2026_03 , released September 17, 2026
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Citation
Carthew, R.W. (2005). Adhesion proteins and the control of cell shape.  Curr. Opin. Genet. Dev. 15(4): 358--363.
FlyBase ID
FBrf0187349
Publication Type
Review
Abstract
The adherens junction functions to connect epithelial cells and maintain their polarized architecture. The geometry of the adherens junction, and consequently the shape of a cell, appears to reach an energetically favorable state. Cadherins within the adherens junction are necessary for cells to achieve this state. However, the view of an adherens junction as a static structure is at odds with the highly dynamic properties of epithelia during development. Interactions between the actin cytoskeleton and the adherens junction are required for certain cell shape changes. Recent insights into adherens junction remodeling have revealed the importance of polarized localization of myosin and Par3 at the adherens junction.
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    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    Curr. Opin. Genet. Dev.
    Title
    Current Opinion in Genetics and Development
    Publication Year
    1991-
    ISBN/ISSN
    0959-437X
    Data From Reference
    Genes (9)